Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
2001 1
2002 1
2003 1
2004 1
2005 1
2006 1
2007 1
2009 3
2010 1
2011 3
2012 3
2014 2
2015 3
2016 1
2017 5
2018 6
2019 2
2020 2
2021 5
2022 1
2023 3
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

43 results

Results by year

Filters applied: . Clear all
The following terms were ignored: %, %
The following terms were not found in PubMed: 20Parker
Page 1
Clinical Pharmacology of Ixazomib: The First Oral Proteasome Inhibitor.
Gupta N, Hanley MJ, Xia C, Labotka R, Harvey RD, Venkatakrishnan K. Gupta N, et al. Clin Pharmacokinet. 2019 Apr;58(4):431-449. doi: 10.1007/s40262-018-0702-1. Clin Pharmacokinet. 2019. PMID: 30117017 Free PMC article. Review.
Ixazomib is a selective, potent, and reversible inhibitor of the 20S proteasome, and preferentially binds to and inhibits the beta5 chymotrypsin-like proteolytic site. ...
Ixazomib is a selective, potent, and reversible inhibitor of the 20S proteasome, and preferentially binds to and inhibits the beta5 c …
Molecular machines for protein degradation.
Groll M, Bochtler M, Brandstetter H, Clausen T, Huber R. Groll M, et al. Chembiochem. 2005 Feb;6(2):222-56. doi: 10.1002/cbic.200400313. Chembiochem. 2005. PMID: 15678420 Review.
One of the most precisely regulated processes in living cells is intracellular protein degradation. The main component of the degradation machinery is the 20S proteasome present in both eukaryotes and prokaryotes. In addition, there exist other proteasome-related protein-d …
One of the most precisely regulated processes in living cells is intracellular protein degradation. The main component of the degradation ma …
The ubiquitin-like modifier FAT10 is degraded by the 20S proteasome in vitro but not in cellulo.
Oliveri F, Keller SJ, Goebel H, Alvarez Salinas GO, Basler M. Oliveri F, et al. Life Sci Alliance. 2023 Apr 3;6(6):e202201760. doi: 10.26508/lsa.202201760. Print 2023 Jun. Life Sci Alliance. 2023. PMID: 37012049 Free PMC article.
Ubiquitin-independent protein degradation via the 20S proteasome without the 19S regulatory particle has gained increasing attention over the last years. The degradation of the ubiquitin-like modifier FAT10 by the 20S proteasome was investigated in this study. We fo …
Ubiquitin-independent protein degradation via the 20S proteasome without the 19S regulatory particle has gained increasing attention …
Phosphatase UBLCP1 controls proteasome assembly.
Sun S, Liu S, Zhang Z, Zeng W, Sun C, Tao T, Lin X, Feng XH. Sun S, et al. Open Biol. 2017 May;7(5):170042. doi: 10.1098/rsob.170042. Open Biol. 2017. PMID: 28539385 Free PMC article.
Here, we show that UBLCP1 selectively binds to the 19S regulatory particle (RP) through its interaction with Rpn1, but not the 20S core particle (CP) or the 26S proteasome holoenzyme. In the RP, UBLCP1 dephosphorylates the subunit Rpt1, impairs its ATPase activity, and con …
Here, we show that UBLCP1 selectively binds to the 19S regulatory particle (RP) through its interaction with Rpn1, but not the 20S co …
The Puzzle of Male Chronophilias.
Seto MC. Seto MC. Arch Sex Behav. 2017 Jan;46(1):3-22. doi: 10.1007/s10508-016-0799-y. Epub 2016 Aug 22. Arch Sex Behav. 2017. PMID: 27549306
In this article, I briefly review research on nepiophilia (infant/toddlers), pedophilia (prepubescent children), hebephilia (pubescent children), ephebophilia (postpubescent, sexually maturing adolescents), teleiophilia (young sexually mature adults, typically 20s and 30s) …
In this article, I briefly review research on nepiophilia (infant/toddlers), pedophilia (prepubescent children), hebephilia (pubescent child …
Proteasome structure, function, and lessons learned from beta-lactone inhibitors.
Groll M, Potts BC. Groll M, et al. Curr Top Med Chem. 2011 Dec;11(23):2850-78. doi: 10.2174/156802611798281320. Curr Top Med Chem. 2011. PMID: 21824111 Review.
Structural studies revealed that the 26S proteasome comprises up to two 19S regulatory caps flanking a cylindrical 20S core particle, which houses the proteolytic subunits and is present in all kingdoms of life. This review highlights current understanding of 20S ar …
Structural studies revealed that the 26S proteasome comprises up to two 19S regulatory caps flanking a cylindrical 20S core particle, …
Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach.
Groll M, Huber R. Groll M, et al. Biochim Biophys Acta. 2004 Nov 29;1695(1-3):33-44. doi: 10.1016/j.bbamcr.2004.09.025. Biochim Biophys Acta. 2004. PMID: 15571807 Free article. Review.
N-Acetyl-Leu-Leu-Norleucinal (Ac-LLN-al, also termed calpain inhibitor I) was one of the first proteasome inhibitors discovered and has been widely used to study the 20S proteasome core particle (CP) function in vivo, despite its lack of specificity. ...
N-Acetyl-Leu-Leu-Norleucinal (Ac-LLN-al, also termed calpain inhibitor I) was one of the first proteasome inhibitors discovered and has been …
Molecular shredders: how proteasomes fulfill their role.
Groll M, Clausen T. Groll M, et al. Curr Opin Struct Biol. 2003 Dec;13(6):665-73. doi: 10.1016/j.sbi.2003.10.005. Curr Opin Struct Biol. 2003. PMID: 14675543 Review.
The 20S proteasome is a large, cylinder-shaped protease that is found in all domains of life and plays a crucial role in cellular protein turnover. ...Although this kind of self-compartmentalization is generally conserved, the proteasomes of bacteria, archaea and eukaryote …
The 20S proteasome is a large, cylinder-shaped protease that is found in all domains of life and plays a crucial role in cellular pro …
"I just wanted more": Hereditary cancer syndromes patients' perspectives on the utility of circulating tumour DNA testing for cancer screening.
Adi-Wauran E, Clausen M, Shickh S, Gagliardi AR, Denburg A, Oldfield LE, Sam J, Reble E, Krishnapillai S, Regier DA, Baxter NN, Dawson L, Penney LS, Foulkes W, Basik M, Sun S, Schrader KA, Karsan A, Pollett A, Pugh TJ; CHARM consortium; Kim RH, Bombard Y. Adi-Wauran E, et al. Eur J Hum Genet. 2024 Feb;32(2):176-181. doi: 10.1038/s41431-023-01473-y. Epub 2023 Oct 11. Eur J Hum Genet. 2024. PMID: 37821757
Thirty HCS patients were interviewed (n = 19 women, age range 20s-70s, n = 25 were white). Participants were highly concerned about developing cancers, particularly those without reliable screening options for early detection. ...
Thirty HCS patients were interviewed (n = 19 women, age range 20s-70s, n = 25 were white). Participants were highly concerned about d …
Three synchronous gastrointestinal tumours.
Boland BM, Collins CG, Christiansen E, O'Brien A, Duignan J. Boland BM, et al. Ir J Med Sci. 2011 Dec;180(4):897-900. doi: 10.1007/s11845-009-0295-7. Epub 2009 Mar 17. Ir J Med Sci. 2011. PMID: 19291353
Carcinoid tumours are similarly uncommon, rarely occurring in Meckel's diverticula but are still the commonest tumour of Meckel's diverticulae [Nies et al. in Dis Colon Rectum 35(6):589-596, 1992; Modlin and Lye in Cancer 97(4):934-959, 2003; Sutter et al. in Schweiz Med Wochensc …
Carcinoid tumours are similarly uncommon, rarely occurring in Meckel's diverticula but are still the commonest tumour of Meckel's diverticul …
43 results