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Multiplex LC-MS/MS Assays for Clinical Bioanalysis of MEDI4276, an Antibody-Drug Conjugate of Tubulysin Analogue Attached via Cleavable Linker to a Biparatopic Humanized Antibody against HER-2.
Faria M, Peay M, Lam B, Ma E, Yuan M, Waldron M, Mylott WR Jr, Liang M, Rosenbaum AI. Faria M, et al. Antibodies (Basel). 2019 Jan 11;8(1):11. doi: 10.3390/antib8010011. Antibodies (Basel). 2019. PMID: 31544817 Free PMC article.
Comparison of a stable isotope labeled (SIL) peptide and an extended SIL peptide as internal standards to track digestion variability of an unstable signature peptide during quantification of a cancer biomarker, human osteopontin, from plasma using capillary microflow LC-MS/MS.
Faria M, Halquist MS, Yuan M, Mylott W Jr, Jenkins RG, Karnes HT. Faria M, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Sep 15;1001:156-68. doi: 10.1016/j.jchromb.2015.05.040. Epub 2015 Jul 26. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 26279007
Liquid chromatography-tandem mass spectrometry method for quantification of thymidine kinase activity in human serum by monitoring the conversion of 3'-deoxy-3'-fluorothymidine to 3'-deoxy-3'-fluorothymidine monophosphate.
Faria M, Halquist MS, Kindt E, Li W, Karnes HT, O'Brien PJ. Faria M, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Oct 15;907:13-20. doi: 10.1016/j.jchromb.2012.08.024. Epub 2012 Aug 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22995377
Multifaceted Bioanalytical Methods for the Comprehensive Pharmacokinetic and Catabolic Assessment of MEDI3726, an Anti-PSMA PBD Antibody-Drug Conjugate.
Huang Y, Del Nagro CJ, Balic K, Mylott WR, Ismaiel OA, Ma E, Faria M, Wheeler AM, Yuan M, Waldron MP, Peay MG, Cortes DF, Roskos L, Liang M, Rosenbaum AI. Huang Y, et al. Among authors: Faria M. Anal Chem. 2020 May 27. doi: 10.1021/acs.analchem.0c01187. Online ahead of print. Anal Chem. 2020. PMID: 32459957