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Structure of N-myristoyltransferase with bound myristoylCoA and peptide substrate analogs.
Bhatnagar RS, Fütterer K, Farazi TA, Korolev S, Murray CL, Jackson-Machelski E, Gokel GW, Gordon JI, Waksman G. Bhatnagar RS, et al. Nat Struct Biol. 1998 Dec;5(12):1091-7. doi: 10.1038/4202. Nat Struct Biol. 1998. PMID: 9846880
N-myristoyltransferase (Nmt) attaches myristate to the N-terminal glycine of many important eukaryotic and viral proteins. ...A novel catalytic mechanism is proposed involving deprotonation of the N-terminal ammonium of a peptide substrate by the enzyme's C-t
N-myristoyltransferase (Nmt) attaches myristate to the N-terminal glycine of many important eukaryotic and viral proteins. ...
The first examples of chemical modification of oligomycin A.
Lysenkova LN, Turchin KF, Danilenko VN, Korolev AM, Preobrazhenskaya MN. Lysenkova LN, et al. J Antibiot (Tokyo). 2010 Jan;63(1):17-22. doi: 10.1038/ja.2009.112. Epub 2009 Nov 13. J Antibiot (Tokyo). 2010. PMID: 19911026
The structures of the compounds obtained were supported by NMR and mass spectrometry methods including the (15)N-labeling of compounds....
The structures of the compounds obtained were supported by NMR and mass spectrometry methods including the (15)N-labeling of compound …
New guanidine-containing nanocomposites impeding the growth of Staphylococcus epidermidis 33 and the biofilm formation.
Gorbunova M, Lemkina L. Gorbunova M, et al. J Biomed Mater Res A. 2016 Mar;104(3):630-638. doi: 10.1002/jbm.a.35596. Epub 2015 Nov 14. J Biomed Mater Res A. 2016. PMID: 26489040
New water-soluble nanocomposites (AgNCs) based on Ag and copolymers of 2,2-diallyl-1,1,3,3-tetraethylguanidiniumchloride with N-vinylpyrrolidone [poly(AGC-VP)] and vinylacetate [poly(AGC-VA)] have been developed. ...
New water-soluble nanocomposites (AgNCs) based on Ag and copolymers of 2,2-diallyl-1,1,3,3-tetraethylguanidiniumchloride with N-vinyl …
[Sequencing and analysis of the resistome of Streptomyces fradiae ATCC19609 in order to develop a test system for screening of new antimicrobial agents].
Vatlin AA, Bekker OB, Lysenkova LN, Korolev AM, Shchekotikhin AE, Danilenko VN. Vatlin AA, et al. Genetika. 2016 Jun;52(6):723-7. Genetika. 2016. PMID: 29368834 Russian.
These included classical antibiotic resistance genes (nine aminoglycoside phosphotransferase genes, two beta-lactamase genes, and the genes of puromycin N-acetyltransferase, phosphinothricin N-acetyltransferase, and aminoglycoside acetyltransferase); the genes of AT …
These included classical antibiotic resistance genes (nine aminoglycoside phosphotransferase genes, two beta-lactamase genes, and the genes …
Risk Related to Pre-Diabetes Mellitus and Diabetes Mellitus in Heart Failure With Reduced Ejection Fraction: Insights From Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure Trial.
Kristensen SL, Preiss D, Jhund PS, Squire I, Cardoso JS, Merkely B, Martinez F, Starling RC, Desai AS, Lefkowitz MP, Rizkala AR, Rouleau JL, Shi VC, Solomon SD, Swedberg K, Zile MR, McMurray JJ, Packer M; PARADIGM-HF Investigators and Committees. Kristensen SL, et al. Circ Heart Fail. 2016 Jan;9(1):e002560. doi: 10.1161/CIRCHEARTFAILURE.115.002560. Circ Heart Fail. 2016. PMID: 26754626 Free PMC article. Clinical Trial.

METHODS AND RESULTS: We examined clinical outcomes in 8399 patients with heart failure and reduced ejection fraction according to history of diabetes mellitus and glycemic status (baseline hemoglobin A1c [HbA1c]: < 6.0% [< 42 mmol/mol], 6.0%-6.4% [42-47 mmol/mol; pre-diabet

METHODS AND RESULTS: We examined clinical outcomes in 8399 patients with heart failure and reduced ejection fraction according to history of …
X-ray Generated Recombination Exciplexes of Substituted Diphenylacetylenes with Tertiary Amines: A Versatile Experimental Vehicle for Targeted Creation of Deep-Blue Electroluminescent Systems.
Melnikov AR, Davydova MP, Sherin PS, Korolev VV, Stepanov AA, Kalneus EV, Benassi E, Vasilevsky SF, Stass DV. Melnikov AR, et al. J Phys Chem A. 2018 Feb 8;122(5):1235-1252. doi: 10.1021/acs.jpca.7b11634. Epub 2018 Jan 24. J Phys Chem A. 2018. PMID: 29283574
Despite varying and rather poor intrinsic emission properties, diphenylacetylene and its prototypical methoxy (donor) or trifluoromethyl (acceptor) monosubstituted derivatives readily form recombination exciplexes with N,N-dimethylaniline and other tertiary amines t …
Despite varying and rather poor intrinsic emission properties, diphenylacetylene and its prototypical methoxy (donor) or trifluoromethyl (ac …
Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability.
Korolev S, Nayal M, Barnes WM, Di Cera E, Waksman G. Korolev S, et al. Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9264-8. doi: 10.1073/pnas.92.20.9264. Proc Natl Acad Sci U S A. 1995. PMID: 7568114 Free PMC article.
The C-terminal domain is identical in fold to the equivalent region of the Klenow fragment of Escherichia coli DNA polymerase I (Klenow pol I). Although the N-terminal domain of Klentaq1 differs greatly in sequence from its counterpart in Klenow pol I, it has clearly evolv …
The C-terminal domain is identical in fold to the equivalent region of the Klenow fragment of Escherichia coli DNA polymerase I (Klenow pol …
13 results