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Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes.
Kleinnijenhuis J, Quintin J, Preijers F, Joosten LA, Ifrim DC, Saeed S, Jacobs C, van Loenhout J, de Jong D, Stunnenberg HG, Xavier RJ, van der Meer JW, van Crevel R, Netea MG. Kleinnijenhuis J, et al. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17537-42. doi: 10.1073/pnas.1202870109. Epub 2012 Sep 17. Proc Natl Acad Sci U S A. 2012. PMID: 22988082 Free PMC article.
Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients.
Ridker PM, Revkin J, Amarenco P, Brunell R, Curto M, Civeira F, Flather M, Glynn RJ, Gregoire J, Jukema JW, Karpov Y, Kastelein JJP, Koenig W, Lorenzatti A, Manga P, Masiukiewicz U, Miller M, Mosterd A, Murin J, Nicolau JC, Nissen S, Ponikowski P, Santos RD, Schwartz PF, Soran H, White H, Wright RS, Vrablik M, Yunis C, Shear CL, Tardif JC; SPIRE Cardiovascular Outcome Investigators. Ridker PM, et al. N Engl J Med. 2017 Apr 20;376(16):1527-1539. doi: 10.1056/NEJMoa1701488. Epub 2017 Mar 17. N Engl J Med. 2017. PMID: 28304242 Free article. Clinical Trial.
A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
NIHR Global Health Research Unit on Global Surgery; STARSurg Collaborative. NIHR Global Health Research Unit on Global Surgery, et al. Lancet Digit Health. 2024 Jul;6(7):e507-e519. doi: 10.1016/S2589-7500(24)00065-7. Lancet Digit Health. 2024. PMID: 38906616 Free article.
Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection.
Ali YM, Hayat A, Saeed BM, Haleem KS, Alshamrani S, Kenawy HI, Ferreira VP, Saggu G, Buchberger A, Lachmann PJ, Sim RB, Goundis D, Andrew PW, Lynch NJ, Schwaeble WJ. Ali YM, et al. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5301-6. doi: 10.1073/pnas.1401011111. Epub 2014 Mar 24. Proc Natl Acad Sci U S A. 2014. PMID: 24706855 Free PMC article.
Here we report the successful therapeutic application of a complement component, a recombinant form of properdin (Pn), with significantly higher activity than native properdin, which promotes complement activation via the alternative pathway, affording protection against N …
Here we report the successful therapeutic application of a complement component, a recombinant form of properdin (Pn), with significantly hi …
On the roles of close shell interactions in the structure of acyl-substituted hydrazones: An experimental and theoretical approach.
Saeed A, Ifzan Arshad M, Bolte M, Fantoni AC, Delgado Espinoza ZY, Erben MF. Saeed A, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2016 Mar 15;157:138-145. doi: 10.1016/j.saa.2015.12.026. Epub 2015 Dec 24. Spectrochim Acta A Mol Biomol Spectrosc. 2016. PMID: 26761413
The X-ray structure determination corroborates that the molecule is present in the crystal as the hydrazone tautomer, probably favored by a strong intramolecular N-H...O=C hydrogen bond occurring between the carbonyl (-C=O) and the hydrazone -C=N-NH- groups. ...The …
The X-ray structure determination corroborates that the molecule is present in the crystal as the hydrazone tautomer, probably favored by a …
Investigating the influence of molybdenum disulfide quantum dots coated with DSPE-PEG-TPP on molecular structures of liver lipids and proteins: An in vivo study.
Ageeli AA, Osrah B, Alosaimi AM, Alwafi R, Alghamdi SA, Saeed A. Ageeli AA, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Nov 5;320:124675. doi: 10.1016/j.saa.2024.124675. Epub 2024 Jun 17. Spectrochim Acta A Mol Biomol Spectrosc. 2024. PMID: 38906057
In this study, we systematically investigated the impact of MoS(2) QDs coated with 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethyleneglycol)-2000](DPSE-PEG) linked with (3-carboxypropyl)triphenyl-phosphonium-bromide (TPP) on molecular structures of hepat …
In this study, we systematically investigated the impact of MoS(2) QDs coated with 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- …
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