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2014 1
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34 results

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Page 1
New Multifunctional Agents for Potential Alzheimer's Disease Treatment Based on Tacrine Conjugates with 2-Arylhydrazinylidene-1,3-Diketones.
Elkina NA, Grishchenko MV, Shchegolkov EV, Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Lushchekina SV, Astakhova TY, Radchenko EV, Palyulin VA, Zhilina EF, Perminova AN, Lapshin LS, Burgart YV, Saloutin VI, Richardson RJ. Elkina NA, et al. Among authors: boltneva np. Biomolecules. 2022 Oct 24;12(11):1551. doi: 10.3390/biom12111551. Biomolecules. 2022. PMID: 36358901 Free PMC article.
Powerful Potential of Polyfluoroalkyl-Containing 4-Arylhydrazinylidenepyrazol-3-ones for Pharmaceuticals.
Burgart YV, Elkina NA, Shchegolkov EV, Krasnykh OP, Makhaeva GF, Triandafilova GA, Solodnikov SY, Boltneva NP, Rudakova EV, Kovaleva NV, Serebryakova OG, Ulitko MV, Borisevich SS, Gerasimova NA, Evstigneeva NP, Kozlov SA, Korolkova YV, Minin AS, Belousova AV, Mozhaitsev ES, Klabukov AM, Saloutin VI. Burgart YV, et al. Among authors: boltneva np. Molecules. 2022 Dec 21;28(1):59. doi: 10.3390/molecules28010059. Molecules. 2022. PMID: 36615256 Free PMC article.
Synthesis of 4-Aminopyrazol-5-ols as Edaravone Analogs and Their Antioxidant Activity.
Burgart YV, Makhaeva GF, Krasnykh OP, Borisevich SS, Agafonova NA, Kovaleva NV, Boltneva NP, Rudakova EV, Shchegolkov EV, Triandafilova GA, Gazizov DA, Serebryakova OG, Ulitko MV, Khursan SL, Saloutin VI, Richardson RJ. Burgart YV, et al. Among authors: boltneva np. Molecules. 2022 Nov 9;27(22):7722. doi: 10.3390/molecules27227722. Molecules. 2022. PMID: 36431823 Free PMC article.
2-Arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropanoic acids as selective and effective carboxylesterase inhibitors with powerful antioxidant potential.
Burgart YV, Makhaeva GF, Khudina OG, Krasnykh OP, Kovaleva NV, Elkina NA, Boltneva NP, Rudakova EV, Lushchekina SV, Shchegolkov EV, Triandafilova GA, Malysheva KO, Serebryakova OG, Borisevich SS, Ilyina MG, Zhilina EF, Saloutin VI, Charushin VN, Richardson RJ. Burgart YV, et al. Among authors: boltneva np. Bioorg Med Chem. 2024 Dec 1;115:117938. doi: 10.1016/j.bmc.2024.117938. Epub 2024 Oct 3. Bioorg Med Chem. 2024. PMID: 39504592
Overview of novel multifunctional agents based on conjugates of γ-carbolines, carbazoles, tetrahydrocarbazoles, phenothiazines, and aminoadamantanes for treatment of Alzheimer's disease.
Makhaeva GF, Shevtsova EF, Boltneva NP, Lushchekina SV, Kovaleva NV, Rudakova EV, Bachurin SO, Richardson RJ. Makhaeva GF, et al. Among authors: boltneva np. Chem Biol Interact. 2019 Aug 1;308:224-234. doi: 10.1016/j.cbi.2019.05.020. Epub 2019 May 14. Chem Biol Interact. 2019. PMID: 31100279 Review.
Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease.
Grishchenko MV, Makhaeva GF, Burgart YV, Rudakova EV, Boltneva NP, Kovaleva NV, Serebryakova OG, Lushchekina SV, Astakhova TY, Zhilina EF, Shchegolkov EV, Richardson RJ, Saloutin VI. Grishchenko MV, et al. Among authors: boltneva np. ChemMedChem. 2022 May 18;17(10):e202200080. doi: 10.1002/cmdc.202200080. Epub 2022 Mar 23. ChemMedChem. 2022. PMID: 35322571 Free PMC article.
Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease.
Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Grishchenko MV, Lushchekina SV, Astakhova TY, Serebryakova OG, Timokhina EN, Zhilina EF, Shchegolkov EV, Ulitko MV, Radchenko EV, Palyulin VA, Burgart YV, Saloutin VI, Bachurin SO, Richardson RJ. Makhaeva GF, et al. Among authors: boltneva np. Int J Mol Sci. 2023 Jan 24;24(3):2285. doi: 10.3390/ijms24032285. Int J Mol Sci. 2023. PMID: 36768608 Free PMC article.
Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment.
Makhaeva GF, Lushchekina SV, Kovaleva NV, Yu Astakhova T, Boltneva NP, Rudakova EV, Serebryakova OG, Proshin AN, Serkov IV, Trofimova TP, Tafeenko VA, Radchenko EV, Palyulin VA, Fisenko VP, Korábečný J, Soukup O, Richardson RJ. Makhaeva GF, et al. Among authors: boltneva np. Bioorg Chem. 2021 Jul;112:104974. doi: 10.1016/j.bioorg.2021.104974. Epub 2021 May 21. Bioorg Chem. 2021. PMID: 34029971
Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N-Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile.
Makhaeva GF, Kovaleva NV, Boltneva NP, Rudakova EV, Lushchekina SV, Astakhova TY, Serkov IV, Proshin AN, Radchenko EV, Palyulin VA, Korabecny J, Soukup O, Bachurin SO, Richardson RJ. Makhaeva GF, et al. Among authors: boltneva np. Molecules. 2022 Feb 4;27(3):1060. doi: 10.3390/molecules27031060. Molecules. 2022. PMID: 35164325 Free PMC article.
Arachidonoylcholine and Other Unsaturated Long-Chain Acylcholines Are Endogenous Modulators of the Acetylcholine Signaling System.
Akimov MG, Kudryavtsev DS, Kryukova EV, Fomina-Ageeva EV, Zakharov SS, Gretskaya NM, Zinchenko GN, Serkov IV, Makhaeva GF, Boltneva NP, Kovaleva NV, Serebryakova OG, Lushchekina SV, Palikov VA, Palikova Y, Dyachenko IA, Kasheverov IE, Tsetlin VI, Bezuglov VV. Akimov MG, et al. Among authors: boltneva np. Biomolecules. 2020 Feb 12;10(2):283. doi: 10.3390/biom10020283. Biomolecules. 2020. PMID: 32059521 Free PMC article.
34 results