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The following term was not found in PubMed: Ranjijafaroudi
Page 1
Selective and Potent Molecular Glue Degraders for NIMA-Related Kinase 7.
Chen L, Huang L, Wen W, Zeng P, Wu Y, Han Q, Chen X, Guo Z, Yu H, Lu W, Jiang B. Chen L, et al. Angew Chem Int Ed Engl. 2025 Mar 17;64(12):e202500169. doi: 10.1002/anie.202500169. Epub 2025 Feb 21. Angew Chem Int Ed Engl. 2025. PMID: 39927695
Here, we developed a novel glutarimide analog with a tetrahydroimidazo[1,2-a]pyrazine scaffold that exhibited strong NIMA-related kinase 7 (NEK7) degradation potential. Further optimization led to the identification of LC-04-045 as a leading NEK7 MGD candidate, demonstrati …
Here, we developed a novel glutarimide analog with a tetrahydroimidazo[1,2-a]pyrazine scaffold that exhibited strong NIMA-related kin …
NEK-mediated barrier regulation.
Barabutis N. Barabutis N. Pulm Pharmacol Ther. 2024 Sep;86:102313. doi: 10.1016/j.pupt.2024.102313. Epub 2024 Jun 21. Pulm Pharmacol Ther. 2024. PMID: 38909830
Tolerance to non-inherited maternal antigen is sustained by LysM+ CD11c+ maternal microchimeric cells.
Peng Y, Pham G, Sun J, Adhikari U, Kumar S, Shao TY, Kinder JM, Turner LH, Way SS. Peng Y, et al. Immunity. 2025 Sep 9;58(9):2176-2189.e3. doi: 10.1016/j.immuni.2025.08.005. Epub 2025 Sep 2. Immunity. 2025. PMID: 40902588 Free PMC article.
Here, we studied maternal microchimeric cells (MMc) that sustain non-inherited maternal antigen (NIMA) tolerance. Complete MMc depletion overturned hallmark features of NIMA-specific tolerance including FOXP3(+) regulatory T cell expansion and cross-generational res …
Here, we studied maternal microchimeric cells (MMc) that sustain non-inherited maternal antigen (NIMA) tolerance. Complete MMc deplet …
NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA.
Yamamoto Y, Chino H, Tsukamoto S, Ode KL, Ueda HR, Mizushima N. Yamamoto Y, et al. Nat Commun. 2021 Jun 2;12(1):3292. doi: 10.1038/s41467-021-23599-7. Nat Commun. 2021. PMID: 34078910 Free PMC article.
Autophagy regulates primary cilia formation, but the underlying mechanism is not fully understood. In this study, we identify NIMA-related kinase 9 (NEK9) as a GABARAPs-interacting protein and find that NEK9 and its LC3-interacting region (LIR) are required for primary cil …
Autophagy regulates primary cilia formation, but the underlying mechanism is not fully understood. In this study, we identify NIMA-re …
Activity and Affinity of Pin1 Variants.
Born A, Henen MA, Vögeli B. Born A, et al. Molecules. 2019 Dec 20;25(1):36. doi: 10.3390/molecules25010036. Molecules. 2019. PMID: 31861908 Free PMC article. Review.
Role of NEK2 in tumorigenesis and tumor progression.
Xia J, Zhao H, Edmondson JL, Koss B, Zhan F. Xia J, et al. Trends Mol Med. 2025 Jan;31(1):79-93. doi: 10.1016/j.molmed.2024.07.013. Epub 2024 Aug 24. Trends Mol Med. 2025. PMID: 39181803 Free PMC article. Review.
Never in mitosis A (NIMA)-related kinase 2 (NEK2) is a serine/threonine kinase found in the nucleus and cytoplasm throughout the cell cycle. ...
Never in mitosis A (NIMA)-related kinase 2 (NEK2) is a serine/threonine kinase found in the nucleus and cytoplasm throughout the cell …
3,797 results