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Page 1
Structural basis for substrate selection by the SARS-CoV-2 replicase.
Malone BF, Perry JK, Olinares PDB, Lee HW, Chen J, Appleby TC, Feng JY, Bilello JP, Ng H, Sotiris J, Ebrahim M, Chua EYD, Mendez JH, Eng ET, Landick R, Götte M, Chait BT, Campbell EA, Darst SA. Malone BF, et al. Among authors: olinares pdb. Nature. 2023 Feb;614(7949):781-787. doi: 10.1038/s41586-022-05664-3. Epub 2023 Feb 1. Nature. 2023. PMID: 36725929 Free PMC article.
Dynamic regulation of TFH selection during the germinal centre reaction.
Merkenschlager J, Finkin S, Ramos V, Kraft J, Cipolla M, Nowosad CR, Hartweger H, Zhang W, Olinares PDB, Gazumyan A, Oliveira TY, Chait BT, Nussenzweig MC. Merkenschlager J, et al. Among authors: olinares pdb. Nature. 2021 Mar;591(7850):458-463. doi: 10.1038/s41586-021-03187-x. Epub 2021 Feb 3. Nature. 2021. PMID: 33536617 Free PMC article.
Using a Function-First "Scout Fragment"-Based Approach to Develop Allosteric Covalent Inhibitors of Conformationally Dynamic Helicase Mechanoenzymes.
Ramsey JR, Shelton PMM, Heiss TK, Olinares PDB, Vostal LE, Soileau H, Grasso M, Casebeer SW, Adaniya S, Miller M, Sun S, Huggins DJ, Myers RW, Chait BT, Vinogradova EV, Kapoor TM. Ramsey JR, et al. Among authors: olinares pdb. J Am Chem Soc. 2024 Jan 10;146(1):62-67. doi: 10.1021/jacs.3c10581. Epub 2023 Dec 22. J Am Chem Soc. 2024. PMID: 38134034 Free PMC article.
Stepwise Promoter Melting by Bacterial RNA Polymerase.
Chen J, Chiu C, Gopalkrishnan S, Chen AY, Olinares PDB, Saecker RM, Winkelman JT, Maloney MF, Chait BT, Ross W, Gourse RL, Campbell EA, Darst SA. Chen J, et al. Among authors: olinares pdb. Mol Cell. 2020 Apr 16;78(2):275-288.e6. doi: 10.1016/j.molcel.2020.02.017. Epub 2020 Mar 10. Mol Cell. 2020. PMID: 32160514 Free PMC article.
Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2.
Mast FD, Fridy PC, Ketaren NE, Wang J, Jacobs EY, Olivier JP, Sanyal T, Molloy KR, Schmidt F, Rutkowska M, Weisblum Y, Rich LM, Vanderwall ER, Dambrauskas N, Vigdorovich V, Keegan S, Jiler JB, Stein ME, Olinares PDB, Hatziioannou T, Sather DN, Debley JS, Fenyö D, Sali A, Bieniasz PD, Aitchison JD, Chait BT, Rout MP. Mast FD, et al. Among authors: olinares pdb. bioRxiv [Preprint]. 2021 Apr 10:2021.04.08.438911. doi: 10.1101/2021.04.08.438911. bioRxiv. 2021. Update in: Elife. 2021 Dec 07;10:e73027. doi: 10.7554/eLife.73027. PMID: 33851164 Free PMC article. Updated. Preprint.
46 results