Onofrio Laselva - Search Results

Year	Number of Results
2014	1
2016	2
2017	1
2018	3
2019	5
2020	9
2021	11
2022	5

1

Rescue of multiple class II CFTR mutations by elexacaftor+tezacaftor+ivacaftor mediated in part by the dual activities of elexacaftor as both corrector and potentiator.

Laselva O, Bartlett C, Gunawardena TNA, Ouyang H, Eckford PDW, Moraes TJ, Bear CE, Gonska T. Laselva O, et al. Eur Respir J. 2021 Jun 17;57(6):2002774. doi: 10.1183/13993003.02774-2020. Print 2021 Jun. Eur Respir J. 2021. PMID: 33303536 Free PMC article.

2

Generation of functional ciliated cholangiocytes from human pluripotent stem cells.

Ogawa M, Jiang JX, Xia S, Yang D, Ding A, Laselva O, Hernandez M, Cui C, Higuchi Y, Suemizu H, Dorrell C, Grompe M, Bear CE, Ogawa S. Ogawa M, et al. Among authors: laselva o. Nat Commun. 2021 Nov 11;12(1):6504. doi: 10.1038/s41467-021-26764-0. Nat Commun. 2021. PMID: 34764255 Free PMC article.

3

The era of CFTR modulators: improvements made and remaining challenges.

Cuevas-Ocaña S, Laselva O, Avolio J, Nenna R. Cuevas-Ocaña S, et al. Among authors: laselva o. Breathe (Sheff). 2020 Jun;16(2):200016. doi: 10.1183/20734735.0016-2020. Breathe (Sheff). 2020. PMID: 33304402 Free PMC article.

4

Phenotyping Rare CFTR Mutations Reveal Functional Expression Defects Restored by TRIKAFTA^TM.

Laselva O, Ardelean MC, Bear CE. Laselva O, et al. J Pers Med. 2021 Apr 15;11(4):301. doi: 10.3390/jpm11040301. J Pers Med. 2021. PMID: 33920764 Free PMC article.

5

One-Step Formation of Protein-Based Tubular Structures for Functional Devices and Tissues.

Gao W, Vaezzadeh N, Chow K, Chen H, Lavender P, Jeronimo MD, McAllister A, Laselva O, Jiang JX, Gage BK, Ogawa S, Ramchandran A, Bear CE, Keller GM, Günther A. Gao W, et al. Among authors: laselva o. Adv Healthc Mater. 2021 Apr;10(8):e2001746. doi: 10.1002/adhm.202001746. Epub 2021 Mar 10. Adv Healthc Mater. 2021. PMID: 33694327

6

Identification of binding sites for ivacaftor on the cystic fibrosis transmembrane conductance regulator.

Laselva O, Qureshi Z, Zeng ZW, Petrotchenko EV, Ramjeesingh M, Hamilton CM, Huan LJ, Borchers CH, Pomès R, Young R, Bear CE. Laselva O, et al. iScience. 2021 May 15;24(6):102542. doi: 10.1016/j.isci.2021.102542. eCollection 2021 Jun 25. iScience. 2021. PMID: 34142049 Free PMC article.

7

Anti-Inflammatory and Anti-Oxidant Effect of Dimethyl Fumarate in Cystic Fibrosis Bronchial Epithelial Cells.

Laselva O, Allegretta C, Di Gioia S, Avolio C, Conese M. Laselva O, et al. Cells. 2021 Aug 19;10(8):2132. doi: 10.3390/cells10082132. Cells. 2021. PMID: 34440900 Free PMC article.

8

High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids.

Xia S, Bozóky Z, Di Paola M, Laselva O, Ahmadi S, Jiang JX, Pitstick AL, Jiang C, Rotin D, Mayhew CN, Jones NL, Bear CE. Xia S, et al. Among authors: laselva o. Cells. 2021 Dec 4;10(12):3419. doi: 10.3390/cells10123419. Cells. 2021. PMID: 34943927 Free PMC article.

9

A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients.

Jiang JX, Wellhauser L, Laselva O, Utkina I, Bozoky Z, Gunawardena T, Ngan Z, Xia S, Di Paola M, Eckford PDW, Ratjen F, Moraes TJ, Parkinson J, Wong AP, Bear CE. Jiang JX, et al. Among authors: laselva o. Stem Cell Reports. 2021 Nov 9;16(11):2825-2837. doi: 10.1016/j.stemcr.2021.09.020. Epub 2021 Oct 21. Stem Cell Reports. 2021. PMID: 34678210 Free PMC article.

10

Small-molecule drugs for cystic fibrosis: Where are we now?

Laselva O, Guerra L, Castellani S, Favia M, Di Gioia S, Conese M. Laselva O, et al. Pulm Pharmacol Ther. 2022 Feb;72:102098. doi: 10.1016/j.pupt.2021.102098. Epub 2021 Nov 15. Pulm Pharmacol Ther. 2022. PMID: 34793977 Review.

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