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Recent advances of the Povarov reaction in medicinal chemistry.

Ghashghaei O, Masdeu C, Alonso C, Palacios F, Lavilla R. Ghashghaei O, et al. Drug Discov Today Technol. 2018 Nov;29:71-79. doi: 10.1016/j.ddtec.2018.08.004. Epub 2018 Aug 28. Drug Discov Today Technol. 2018. PMID: 30471676 Review.

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Selectivity in multiple multicomponent reactions: types and synthetic applications.

Ghashghaei O, Seghetti F, Lavilla R. Ghashghaei O, et al. Beilstein J Org Chem. 2019 Feb 21;15:521-534. doi: 10.3762/bjoc.15.46. eCollection 2019. Beilstein J Org Chem. 2019. PMID: 30873236 Free PMC article. Review.

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New Trimethoprim-Like Molecules: Bacteriological Evaluation and Insights into Their Action.

Jorba M, Pedrola M, Ghashghaei O, Herráez R, Campos-Vicens L, Luque FJ, Lavilla R, Viñas M. Jorba M, et al. Among authors: ghashghaei o. Antibiotics (Basel). 2021 Jun 12;10(6):709. doi: 10.3390/antibiotics10060709. Antibiotics (Basel). 2021. PMID: 34204647 Free PMC article.

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Extended Multicomponent Reactions with Indole Aldehydes: Access to Unprecedented Polyheterocyclic Scaffolds, Ligands of the Aryl Hydrocarbon Receptor.

Ghashghaei O, Pedrola M, Seghetti F, Martin VV, Zavarce R, Babiak M, Novacek J, Hartung F, Rolfes KM, Haarmann-Stemmann T, Lavilla R. Ghashghaei O, et al. Angew Chem Int Ed Engl. 2021 Feb 1;60(5):2603-2608. doi: 10.1002/anie.202011253. Epub 2020 Nov 26. Angew Chem Int Ed Engl. 2021. PMID: 33048416

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Multiple Multicomponent Reactions: Unexplored Substrates, Selective Processes, and Versatile Chemotypes in Biomedicine.

Ghashghaei O, Caputo S, Sintes M, Revés M, Kielland N, Estarellas C, Luque FJ, Aviñó A, Eritja R, Serna-Gallego A, Marrugal-Lorenzo JA, Pachón J, Sánchez-Céspedes J, Treadwell R, de Moliner F, Vendrell M, Lavilla R. Ghashghaei O, et al. Chemistry. 2018 Sep 25;24(54):14513-14521. doi: 10.1002/chem.201802877. Epub 2018 Aug 28. Chemistry. 2018. PMID: 29974986

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Tetrasubstituted Imidazolium Salts as Potent Antiparasitic Agents against African and American Trypanosomiases.

Ghashghaei O, Kielland N, Revés M, Taylor MC, Kelly JM, Di Pietro O, Muñoz-Torrero D, Pérez B, Lavilla R. Ghashghaei O, et al. Molecules. 2018 Jan 16;23(1):177. doi: 10.3390/molecules23010177. Molecules. 2018. PMID: 29337878 Free PMC article.

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Multicomponent Reactions Upon the Known Drug Trimethoprim as a Source of Novel Antimicrobial Agents.

Pedrola M, Jorba M, Jardas E, Jardi F, Ghashghaei O, Viñas M, Lavilla R. Pedrola M, et al. Among authors: ghashghaei o. Front Chem. 2019 Jul 4;7:475. doi: 10.3389/fchem.2019.00475. eCollection 2019. Front Chem. 2019. PMID: 31334221 Free PMC article.

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A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy-Induced Cancer Cell Death.

Barth ND, Mendive-Tapia L, Subiros-Funosas R, Ghashghaei O, Lavilla R, Maiorino L, He XY, Dransfield I, Egeblad M, Vendrell M. Barth ND, et al. Among authors: ghashghaei o. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202113020. doi: 10.1002/anie.202113020. Epub 2021 Dec 16. Angew Chem Int Ed Engl. 2022. PMID: 34762762 Free PMC article.

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Insertion of Isocyanides into N-Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds.

Kishore KG, Ghashghaei O, Estarellas C, Mestre MM, Monturiol C, Kielland N, Kelly JM, Francisco AF, Jayawardhana S, Muñoz-Torrero D, Pérez B, Luque FJ, Gámez-Montaño R, Lavilla R. Kishore KG, et al. Among authors: ghashghaei o. Angew Chem Int Ed Engl. 2016 Jul 25;55(31):8994-8. doi: 10.1002/anie.201604109. Epub 2016 Jun 17. Angew Chem Int Ed Engl. 2016. PMID: 27314630

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Fluorogenic Trp(redBODIPY) cyclopeptide targeting keratin 1 for imaging of aggressive carcinomas.

Subiros-Funosas R, Ho VCL, Barth ND, Mendive-Tapia L, Pappalardo M, Barril X, Ma R, Zhang CB, Qian BZ, Sintes M, Ghashghaei O, Lavilla R, Vendrell M. Subiros-Funosas R, et al. Among authors: ghashghaei o. Chem Sci. 2019 Dec 18;11(5):1368-1374. doi: 10.1039/c9sc05558d. Chem Sci. 2019. PMID: 34123261 Free PMC article.

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