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Year Number of Results
2002 2
2003 1
2004 3
2005 1
2006 2
2007 2
2008 2
2011 1
2014 5
2015 6
2016 6
2017 3
2018 2
2021 1
2022 0
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32 results
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Page 1
Progress in the research of artemisinin and its analogues as antimalarials: an update.
Sriram D, Rao VS, Chandrasekhara KV, Yogeeswari P. Sriram D, et al. Nat Prod Res. 2004 Dec;18(6):503-27. doi: 10.1080/14786410310001620556. Nat Prod Res. 2004. PMID: 15595609 Review.
Artemisinin, a sesquiterpene lactone endoperoxide isolated from Artemesia annua has been shown to be a fast acting, safe and effective drug against multidrug-resistant and sensitive strains of P. falciparum. This article reports a survey of the literature dealing with arte …
Artemisinin, a sesquiterpene lactone endoperoxide isolated from Artemesia annua has been shown to be a fast acting, safe and effective drug …
Antinociceptive properties of the aqueous and methanol extracts of the stem bark of Petersianthus macrocarpus (P. Beauv.) Liben (Lecythidaceae) in mice.
Bomba FD, Wandji BA, Piegang BN, Awouafack MD, Sriram D, Yogeeswari P, Kamanyi A, Nguelefack TB. Bomba FD, et al. J Ethnopharmacol. 2015 Nov 4;174:66-73. doi: 10.1016/j.jep.2015.08.004. Epub 2015 Aug 6. J Ethnopharmacol. 2015. PMID: 26256316
ETHNOPHARMACOLOGICAL RELEVANCE: Aqueous maceration from the stem barks of Petersianthus macrocarpus (P. Beauv.) Liben (Lecythidaceae) is taken orally in the central Africa for the management of various ailments, including pain. ...CONCLUSION: These results demonstrate that …
ETHNOPHARMACOLOGICAL RELEVANCE: Aqueous maceration from the stem barks of Petersianthus macrocarpus (P. Beauv.) Liben (Lecythidaceae) …
Antihypernociceptive effects of Petersianthus macrocarpus stem bark on neuropathic pain induced by chronic constriction injury in rats.
Bomba FDT, Nguelefack TB, Matharasala G, Mishra RK, Battu MB, Sriram D, Kamanyi A, Yogeeswari P. Bomba FDT, et al. Inflammopharmacology. 2021 Aug;29(4):1241-1253. doi: 10.1007/s10787-021-00821-y. Epub 2021 Jun 3. Inflammopharmacology. 2021. PMID: 34081248

Both extracts at the employed doses (100 and 200 mg/kg), significantly (p < 0.01 and p < 0.001) reduced the spontaneous pain, tactile and cold allodynia, and mechanical hyperalgesia. The methanolic extract used at the dose of 200 mg/kg significantly reduced th

Both extracts at the employed doses (100 and 200 mg/kg), significantly (p < 0.01 and p < 0.001) reduced the spontaneous

Click-based synthesis and antitubercular evaluation of dibenzofuran tethered thiazolyl-1,2,3-triazolyl acetamides.
Surineni G, Yogeeswari P, Sriram D, Kantevari S. Surineni G, et al. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3684-9. doi: 10.1016/j.bmcl.2016.05.085. Epub 2016 Jun 2. Bioorg Med Chem Lett. 2016. PMID: 27317646
A series of novel dibenzofuran tethered thiazolyl-1,2,3-triazolyl acetamides, designed by assembling antitubercular pharmacophoric fragments, dibenzofuran, 2-aminothiazole and substituted triazoles in one molecular architecture, were evaluated against Mycobacterium tuberculosis. …
A series of novel dibenzofuran tethered thiazolyl-1,2,3-triazolyl acetamides, designed by assembling antitubercular pharmacophoric fragments …
Development of acridine derivatives as selective Mycobacterium tuberculosis DNA gyrase inhibitors.
Medapi B, Meda N, Kulkarni P, Yogeeswari P, Sriram D. Medapi B, et al. Bioorg Med Chem. 2016 Feb 15;24(4):877-85. doi: 10.1016/j.bmc.2016.01.011. Epub 2016 Jan 7. Bioorg Med Chem. 2016. PMID: 26787274
In this study we have designed p-phenylene diamine linked acridine derivative from our earlier reported quinoline-aminopiperidine hybrid MTB DNA gyrase inhibitors with aiming more potency and less cardiotoxicity. ...
In this study we have designed p-phenylene diamine linked acridine derivative from our earlier reported quinoline-aminopiperidine hyb …
Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives.
Ramprasad J, Nayak N, Dalimba U, Yogeeswari P, Sriram D, Peethambar SK, Achur R, Kumar HS. Ramprasad J, et al. Eur J Med Chem. 2015 May 5;95:49-63. doi: 10.1016/j.ejmech.2015.03.024. Epub 2015 Mar 14. Eur J Med Chem. 2015. PMID: 25794789
Seven (5c, 5d, 5l, 5p, 5r, 5z and 5aa) out of twenty nine compounds showed potent anti-tubercular activity with a MIC of 3.125 mug/mL. A p-substituted phenyl group (p-tolyl or p-chlorophenyl) in the imidazo[2,1-b][1,3,4]thiadiazole ring and/or a chloro group …
Seven (5c, 5d, 5l, 5p, 5r, 5z and 5aa) out of twenty nine compounds showed potent anti-tubercular activity with a MIC of 3.125 mug/mL. A …
Clickable conjugates of bile acids and nucleosides: Synthesis, characterization, in vitro anticancer and antituberculosis studies.
Agarwal DS, Siva Krishna V, Sriram D, Yogeeswari P, Sakhuja R. Agarwal DS, et al. Steroids. 2018 Nov;139:35-44. doi: 10.1016/j.steroids.2018.09.006. Epub 2018 Sep 17. Steroids. 2018. PMID: 30236620
A series of clickable bile acid-nucleosides conjugates linked directly or via amino acid linker were synthesized, and characterized by spectroscopic techniques such as (1)H NMR, (13)C NMR, FT-IR, HRMS and HPLC. The synthesized compounds 6a-p were screened for their in vitr …
A series of clickable bile acid-nucleosides conjugates linked directly or via amino acid linker were synthesized, and characterized by spect …
2-Butyl-4-chloroimidazole based substituted piperazine-thiosemicarbazone hybrids as potent inhibitors of Mycobacterium tuberculosis.
Jallapally A, Addla D, Yogeeswari P, Sriram D, Kantevari S. Jallapally A, et al. Bioorg Med Chem Lett. 2014 Dec 1;24(23):5520-4. doi: 10.1016/j.bmcl.2014.09.084. Epub 2014 Oct 5. Bioorg Med Chem Lett. 2014. PMID: 25451998
Here a series of 2-butyl-4-chloroimidazole based substituted piperazine-thiosemicarbazone hybrids were designed by combining three different pharmacophoric fragments in single molecular architecture. 2-Butyl-4-chloro-1-(3-(4-substituted)piperazin-1-yl)propyl)-1H-imidazole-5-carba …
Here a series of 2-butyl-4-chloroimidazole based substituted piperazine-thiosemicarbazone hybrids were designed by combining three different …
32 results