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2003 1
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71 results

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Page 1
Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele.
Middleton PG, Mall MA, Dřevínek P, Lands LC, McKone EF, Polineni D, Ramsey BW, Taylor-Cousar JL, Tullis E, Vermeulen F, Marigowda G, McKee CM, Moskowitz SM, Nair N, Savage J, Simard C, Tian S, Waltz D, Xuan F, Rowe SM, Jain R; VX17-445-102 Study Group. Middleton PG, et al. N Engl J Med. 2019 Nov 7;381(19):1809-1819. doi: 10.1056/NEJMoa1908639. Epub 2019 Oct 31. N Engl J Med. 2019. PMID: 31697873 Free PMC article. Clinical Trial.
A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.
Ghigo A, Murabito A, Sala V, Pisano AR, Bertolini S, Gianotti A, Caci E, Montresor A, Premchandar A, Pirozzi F, Ren K, Della Sala A, Mergiotti M, Richter W, de Poel E, Matthey M, Caldrer S, Cardone RA, Civiletti F, Costamagna A, Quinney NL, Butnarasu C, Visentin S, Ruggiero MR, Baroni S, Crich SG, Ramel D, Laffargue M, Tocchetti CG, Levi R, Conti M, Lu XY, Melotti P, Sorio C, De Rose V, Facchinetti F, Fanelli V, Wenzel D, Fleischmann BK, Mall MA, Beekman J, Laudanna C, Gentzsch M, Lukacs GL, Pedemonte N, Hirsch E. Ghigo A, et al. Among authors: melotti p. Sci Transl Med. 2022 Mar 30;14(638):eabl6328. doi: 10.1126/scitranslmed.abl6328. Epub 2022 Mar 30. Sci Transl Med. 2022. PMID: 35353541 Free PMC article.
Revisiting the Role of Leukocytes in Cystic Fibrosis.
Averna M, Melotti P, Sorio C. Averna M, et al. Among authors: melotti p. Cells. 2021 Dec 1;10(12):3380. doi: 10.3390/cells10123380. Cells. 2021. PMID: 34943888 Free PMC article. Review.
When and how ruling out cystic fibrosis in adult patients with bronchiectasis.
Gramegna A, Aliberti S, Seia M, Porcaro L, Bianchi V, Castellani C, Melotti P, Sorio C, Consalvo E, Franceschi E, Amati F, Contarini M, Gaffuri M, Roncoroni L, Vigone B, Bellofiore A, Del Monaco C, Oriano M, Terranova L, Patria MF, Marchisio P, Assael BM, Blasi F. Gramegna A, et al. Among authors: melotti p. Multidiscip Respir Med. 2018 Aug 9;13(Suppl 1):29. doi: 10.1186/s40248-018-0142-7. eCollection 2018. Multidiscip Respir Med. 2018. PMID: 30151190 Free PMC article. Review.
CFTR function is impaired in a subset of patients with pancreatitis carrying rare CFTR variants.
Angyal D, Kleinfelder K, Ciciriello F, Groeneweg TA, De Marchi G, de Pretis N, Bernardoni L, Rodella L, Tomba F, De Angelis P, Surace C, Pintani E, Alghisi F, de Jonge HR, Melotti P, Sorio C, Lucidi V, Bijvelds MJC, Frulloni L. Angyal D, et al. Among authors: melotti p. Pancreatology. 2024 May;24(3):394-403. doi: 10.1016/j.pan.2024.03.005. Epub 2024 Mar 10. Pancreatology. 2024. PMID: 38493004 Free article.
Real-Life Experience with CFTR Modulators Shows Correction of LAD-IV Phenotype in Cystic Fibrosis.
Montresor A, D'Ulivo B, Preato S, Farinazzo A, Pintani E, Chiara ED, Torroni L, Verlato G, Boscia S, Pisano L, Mangone G, Ricci S, Azzari C, Taccetti G, Terlizzi V, Cipolli M, Melotti P, Sorio C, Laudanna C. Montresor A, et al. Among authors: melotti p. Am J Respir Cell Mol Biol. 2024 Oct;71(4):495-498. doi: 10.1165/rcmb.2024-0136LE. Am J Respir Cell Mol Biol. 2024. PMID: 39352210 No abstract available.
In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells.
Kleinfelder K, Lotti V, Eramo A, Amato F, Lo Cicero S, Castelli G, Spadaro F, Farinazzo A, Dell'Orco D, Preato S, Conti J, Rodella L, Tomba F, Cerofolini A, Baldisseri E, Bertini M, Volpi S, Villella VR, Esposito S, Zollo I, Castaldo G, Laudanna C, Sorsher EJ, Hong J, Joshi D, Cutting G, Lucarelli M, Melotti P, Sorio C. Kleinfelder K, et al. Among authors: melotti p. iScience. 2023 Oct 12;26(11):108180. doi: 10.1016/j.isci.2023.108180. eCollection 2023 Nov 17. iScience. 2023. PMID: 38026150 Free PMC article.
71 results