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Proceedings of the 3rd IPLeiria's International Health Congress : Leiria, Portugal. 6-7 May 2016.
Tomás CC, Oliveira E, Sousa D, Uba-Chupel M, Furtado G, Rocha C, Teixeira A, Ferreira P, Alves C, Gisin S, Catarino E, Carvalho N, Coucelo T, Bonfim L, Silva C, Franco D, González JA, Jardim HG, Silva R, Baixinho CL, Presado MªH, Marques MªF, Cardoso ME, Cunha M, Mendes J, Xavier A, Galhardo A, Couto M, Frade JG, Nunes C, Mesquita JR, Nascimento MS, Gonçalves G, Castro C, Mártires A, Monteiro MªJ, Rainho C, Caballero FP, Monago FM, Guerrero JT, Monago RM, Trigo AP, Gutierrez ML, Milanés GM, Reina MG, Villanueva AG, Piñero AS, Aliseda IR, Ramirez FB, Ribeiro A, Quelhas A, Manso C, Caballero FP, Guerrero JT, Monago FM, Santos RB, Jimenez NR, Nuñez CG, Gomez IR, Fernandez MªJL, Marquez LA, Moreno AL, Huertas MªJT, Ramirez FB, Seabra D, Salvador MªC, Braga L, Parreira P, Salgueiro-Oliveira A, Arreguy-Sena C, Oliveira BF, Henriques MªA, Santos J, Lebre S, Marques A, Festas C, Rodrigues S, Ribeiro A, Lumini J, Figueiredo AG, Hernandez-Martinez FJ, Campi L, Quintana-Montesdeoca MªP, Jimenez-Diaz JF, Rodriguez-De-Vera BC, Parente A, Mata MªA, Pereira AMª, Fernandes A, Brás M, Pinto MªR, Parreira P, Basto ML, Rei AC, Mónico LM, Sousa G, Morna C, Freitas O, Freitas G, Jardim A, Vasconcelos … See abstract for full author list ➔ Tomás CC, et al. BMC Health Serv Res. 2016 Jul 6;16 Suppl 3(Suppl 3):200. doi: 10.1186/s12913-016-1423-5. BMC Health Serv Res. 2016. PMID: 27409075 Free PMC article.
Martins O179 Women's beliefs about pap smear test and cervical cancer: influence of social determinants Ana B Pinheiro, Priscila S. Aquino, Lara L. Oliveira, Patricia C. Pinheiro, Caroline R. Sousa, Vivien A. Freitas, Tatiane M. ...Fontana, Josimari T. Lacerda, P …
Martins O179 Women's beliefs about pap smear test and cervical cancer: influence of social determinants Ana B Pinheiro, Priscila S. Aquino, …
Rates of, and factors associated with, switching among generic levothyroxine preparations in commercially insured American adults.
Brito JP, Deng Y, Ross JS, Choi NH, Graham DJ, Qiang Y, Rantou E, Wang Z, Zhao L, Shah ND, Lipska KJ. Brito JP, et al. Endocrine. 2022 May;76(2):349-358. doi: 10.1007/s12020-022-02987-z. Epub 2022 Feb 2. Endocrine. 2022. PMID: 35107758 Free PMC article.
IMPORTANCE: Some practice guidelines warn against generic L-thyroxine preparation switching. OBJECTIVE: To examine the rates of generic L-thyroxine preparation switching within one year of initiating L-thyroxine, and to examine factors associated with switchi …
IMPORTANCE: Some practice guidelines warn against generic L-thyroxine preparation switching. OBJECTIVE: To examine the rates of gener …
Long-Term Intermittent Exposure to High Altitude Elevates Asymmetric Dimethylarginine in First Exposed Young Adults.
Lüneburg N, Siques P, Brito J, De La Cruz JJ, León-Velarde F, Hannemann J, Ibanez C, Böger RH. Lüneburg N, et al. High Alt Med Biol. 2017 Sep;18(3):226-233. doi: 10.1089/ham.2016.0123. Epub 2017 Apr 28. High Alt Med Biol. 2017. PMID: 28453332 Free PMC article.

Luneburg, Nicole, Patricia Siques, Julio Brito, Juan Jose De La Cruz, Fabiola Leon-Velarde, Juliane Hannemann, Cristian Ibanez, and Rainer Boger. ...The concentrations of ADMA and L-NMMA were higher in CH (3.48 0.07, 0.53 0.08 mumol/L; p < 0.001) as

…
Luneburg, Nicole, Patricia Siques, Julio Brito, Juan Jose De La Cruz, Fabiola Leon-Velarde, Juliane Hannemann, Cristian Ibanez …
Association Between Generic-to-Generic Levothyroxine Switching and Thyrotropin Levels Among US Adults.
Brito JP, Deng Y, Ross JS, Choi NH, Graham DJ, Qiang Y, Rantou E, Wang Z, Zhao L, Shah ND, Lipska KJ. Brito JP, et al. JAMA Intern Med. 2022 Apr 1;182(4):418-425. doi: 10.1001/jamainternmed.2022.0045. JAMA Intern Med. 2022. PMID: 35226058 Free PMC article.
MAIN OUTCOMES AND MEASURES: Proportion of individuals with a normal (0.3-4.4 mIU/L) or markedly abnormal (<0.1 or >10.0 mIU/L) TSH level using the first available laboratory result 6 weeks to 12 months after the index date. ...The mean (SD) TSH levels after th …
MAIN OUTCOMES AND MEASURES: Proportion of individuals with a normal (0.3-4.4 mIU/L) or markedly abnormal (<0.1 or >10.0 mIU/ …
Cardiovascular outcomes and rates of fractures and falls among patients with brand-name versus generic L-thyroxine use.
Brito JP, Ross JS, Deng Y, Sangaralingham L, Graham DJ, Qiang Y, Wang Z, Yao X, Zhao L, Smallridge RC, Bernet V, Shah ND, Lipska KJ. Brito JP, et al. Endocrine. 2021 Dec;74(3):592-602. doi: 10.1007/s12020-021-02779-x. Epub 2021 Jun 5. Endocrine. 2021. PMID: 34089480 Free PMC article.
PURPOSE: To compare cardiovascular outcomes and rates of fractures and falls among patients with persistent brand-name versus generic L-thyroxine use. METHODS: Retrospective, 1:1 propensity-matched longitudinal study using a national administrative claims database to exami …
PURPOSE: To compare cardiovascular outcomes and rates of fractures and falls among patients with persistent brand-name versus generic L …
Thyroid hormone treatment among pregnant women with subclinical hypothyroidism: US national assessment.
Maraka S, Mwangi R, McCoy RG, Yao X, Sangaralingham LR, Singh Ospina NM, O'Keeffe DT, De Ycaza AE, Rodriguez-Gutierrez R, Coddington CC 3rd, Stan MN, Brito JP, Montori VM. Maraka S, et al. BMJ. 2017 Jan 25;356:i6865. doi: 10.1136/bmj.i6865. BMJ. 2017. PMID: 28122781 Free PMC article.
RESULTS: Among 5405 pregnant women with subclinical hypothyroidism, 843 with a mean pre-treatment TSH concentration of 4.8 (SD 1.7) mIU/L were treated with thyroid hormone and 4562 with a mean baseline TSH concentration of 3.3 (SD 0.9) mIU/L were not treated (P<0 …
RESULTS: Among 5405 pregnant women with subclinical hypothyroidism, 843 with a mean pre-treatment TSH concentration of 4.8 (SD 1.7) mIU/L …
Comparative Effectiveness of Generic vs Brand-Name Levothyroxine in Achieving Normal Thyrotropin Levels.
Brito JP, Ross JS, Sangaralingham L, Dutcher SK, Graham DJ, Wang Z, Wu Y, Yao X, Smallridge RC, Bernet V, Shah ND, Lipska KJ. Brito JP, et al. JAMA Netw Open. 2020 Sep 1;3(9):e2017645. doi: 10.1001/jamanetworkopen.2020.17645. JAMA Netw Open. 2020. PMID: 32997127 Free PMC article.
Eligible patients were adults (aged 18 years) with thyrotropin levels ranging from 4.5 to 19.9 mIU/L who initiated use of generic or brand-name levothyroxine from January 1, 2008, to October 1, 2017. ...MAIN OUTCOMES AND MEASURES: Proportion of patients with normal vs mark …
Eligible patients were adults (aged 18 years) with thyrotropin levels ranging from 4.5 to 19.9 mIU/L who initiated use of generic or …
Variation in Treatment Practices for Subclinical Hypothyroidism in Pregnancy: US National Assessment.
Maraka S, Mwangi R, Yao X, Sangaralingham LR, Singh Ospina NM, O'Keeffe DT, Rodriguez-Gutierrez R, Stan MN, Brito JP, Montori VM, McCoy RG. Maraka S, et al. J Clin Endocrinol Metab. 2019 Sep 1;104(9):3893-3901. doi: 10.1210/jc.2019-00057. J Clin Endocrinol Metab. 2019. PMID: 31127823 Free PMC article.
PARTICIPANTS: Pregnant women with SCH defined by untreated TSH 2.5 to 10 mIU/L. MAIN OUTCOME MEASURE: Initiation of LT4 as a function of treating clinician specialty (endocrinology, obstetrics/gynecology, primary care, or other), baseline TSH, patient clinical and demograp …
PARTICIPANTS: Pregnant women with SCH defined by untreated TSH 2.5 to 10 mIU/L. MAIN OUTCOME MEASURE: Initiation of LT4 as a function …