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Year Number of Results
2008 1
2009 1
2010 1
2011 2
2012 1
2013 1
2014 1
2015 2
2016 2
2018 1
2020 2
2021 0
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13 results
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Page 1
Ratiometric biosensors based on dimerization-dependent fluorescent protein exchange.
Ding Y, Li J, Enterina JR, Shen Y, Zhang I, Tewson PH, Mo GC, Zhang J, Quinn AM, Hughes TE, Maysinger D, Alford SC, Zhang Y, Campbell RE. Ding Y, et al. Among authors: tewson ph. Nat Methods. 2015 Mar;12(3):195-8. doi: 10.1038/nmeth.3261. Epub 2015 Jan 26. Nat Methods. 2015. PMID: 25622108 Free PMC article.
Analyzing kinetic signaling data for G-protein-coupled receptors.
Hoare SRJ, Tewson PH, Quinn AM, Hughes TE, Bridge LJ. Hoare SRJ, et al. Among authors: tewson ph. Sci Rep. 2020 Jul 23;10(1):12263. doi: 10.1038/s41598-020-67844-3. Sci Rep. 2020. PMID: 32704081 Free PMC article.
A kinetic method for measuring agonist efficacy and ligand bias using high resolution biosensors and a kinetic data analysis framework.
Hoare SRJ, Tewson PH, Quinn AM, Hughes TE. Hoare SRJ, et al. Among authors: tewson ph. Sci Rep. 2020 Feb 4;10(1):1766. doi: 10.1038/s41598-020-58421-9. Sci Rep. 2020. PMID: 32019973 Free PMC article.
Assay for Detecting Gαi-Mediated Decreases in cAMP in Living Cells.
Tewson P, Martinka S, Shaner N, Berlot C, Quinn AM, Hughes T. Tewson P, et al. SLAS Discov. 2018 Oct;23(9):898-906. doi: 10.1177/2472555218786238. Epub 2018 Jul 10. SLAS Discov. 2018. PMID: 29991302
New DAG and cAMP Sensors Optimized for Live-Cell Assays in Automated Laboratories.
Tewson PH, Martinka S, Shaner NC, Hughes TE, Quinn AM. Tewson PH, et al. J Biomol Screen. 2016 Mar;21(3):298-305. doi: 10.1177/1087057115618608. Epub 2015 Dec 11. J Biomol Screen. 2016. PMID: 26657040 Free PMC article.
PKC-dependent Phosphorylation of the H1 Histamine Receptor Modulates TRPC6 Activity.
Chen X, Egly C, Riley AM, Li W, Tewson P, Hughes TE, Quinn AM, Obukhov AG. Chen X, et al. Among authors: tewson p. Cells. 2014 Apr 4;3(2):247-57. doi: 10.3390/cells3020247. Cells. 2014. PMID: 24709960 Free PMC article.
Cilia have high cAMP levels that are inhibited by Sonic Hedgehog-regulated calcium dynamics.
Moore BS, Stepanchick AN, Tewson PH, Hartle CM, Zhang J, Quinn AM, Hughes TE, Mirshahi T. Moore BS, et al. Among authors: tewson ph. Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13069-13074. doi: 10.1073/pnas.1602393113. Epub 2016 Oct 31. Proc Natl Acad Sci U S A. 2016. PMID: 27799542 Free PMC article.
Simultaneous detection of Ca2+ and diacylglycerol signaling in living cells.
Tewson P, Westenberg M, Zhao Y, Campbell RE, Quinn AM, Hughes TE. Tewson P, et al. PLoS One. 2012;7(8):e42791. doi: 10.1371/journal.pone.0042791. Epub 2012 Aug 17. PLoS One. 2012. PMID: 22912738 Free PMC article.
A multiplexed fluorescent assay for independent second-messenger systems: decoding GPCR activation in living cells.
Tewson PH, Quinn AM, Hughes TE. Tewson PH, et al. J Biomol Screen. 2013 Aug;18(7):797-806. doi: 10.1177/1087057113485427. Epub 2013 Apr 11. J Biomol Screen. 2013. PMID: 23580666 Free PMC article.
Diazoxide-unresponsive congenital hyperinsulinism in children with dominant mutations of the β-cell sulfonylurea receptor SUR1.
Macmullen CM, Zhou Q, Snider KE, Tewson PH, Becker SA, Aziz AR, Ganguly A, Shyng SL, Stanley CA. Macmullen CM, et al. Among authors: tewson ph. Diabetes. 2011 Jun;60(6):1797-804. doi: 10.2337/db10-1631. Epub 2011 May 2. Diabetes. 2011. PMID: 21536946 Free PMC article.
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