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Bioavailability of Glucoraphanin and Sulforaphane from High-Glucoraphanin Broccoli.

Sivapalan T, Melchini A, Saha S, Needs PW, Traka MH, Tapp H, Dainty JR, Mithen RF. Sivapalan T, et al. Among authors: needs pw. Mol Nutr Food Res. 2018 Sep;62(18):e1700911. doi: 10.1002/mnfr.201700911. Epub 2018 Mar 8. Mol Nutr Food Res. 2018. PMID: 29266773 Free PMC article. Clinical Trial.

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Anti-Inflammatory Effects of Quercetin on High-Glucose and Pro-Inflammatory Cytokine Challenged Vascular Endothelial Cell Metabolism.

Ozyel B, Le Gall G, Needs PW, Kroon PA. Ozyel B, et al. Among authors: needs pw. Mol Nutr Food Res. 2021 Mar;65(6):e2000777. doi: 10.1002/mnfr.202000777. Epub 2021 Jan 22. Mol Nutr Food Res. 2021. PMID: 33481349 Free PMC article.

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Plant Bioactives and the Prevention of Prostate Cancer: Evidence from Human Studies.

Livingstone TL, Beasy G, Mills RD, Plumb J, Needs PW, Mithen R, Traka MH. Livingstone TL, et al. Among authors: needs pw. Nutrients. 2019 Sep 18;11(9):2245. doi: 10.3390/nu11092245. Nutrients. 2019. PMID: 31540470 Free PMC article. Review.

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Accumulation of Dietary S-Methyl Cysteine Sulfoxide in Human Prostate Tissue.

Coode-Bate J, Sivapalan T, Melchini A, Saha S, Needs PW, Dainty JR, Maicha JB, Beasy G, Traka MH, Mills RD, Ball RY, Mithen RF. Coode-Bate J, et al. Among authors: needs pw. Mol Nutr Food Res. 2019 Oct;63(20):e1900461. doi: 10.1002/mnfr.201900461. Epub 2019 Sep 11. Mol Nutr Food Res. 2019. PMID: 31410992 Free PMC article.

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Citrus flavanone metabolites protect pancreatic-β cells under oxidative stress induced by cholesterol.

Anacleto SL, Milenkovic D, Kroon PA, Needs PW, Lajolo FM, Hassimotto NMA. Anacleto SL, et al. Among authors: needs pw. Food Funct. 2020 Oct 21;11(10):8612-8624. doi: 10.1039/d0fo01839b. Food Funct. 2020. PMID: 32959863

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Quantitative Dietary Fingerprinting (QDF)-A Novel Tool for Comprehensive Dietary Assessment Based on Urinary Nutrimetabolomics.

González-Domínguez R, Urpi-Sarda M, Jáuregui O, Needs PW, Kroon PA, Andrés-Lacueva C. González-Domínguez R, et al. Among authors: needs pw. J Agric Food Chem. 2020 Feb 19;68(7):1851-1861. doi: 10.1021/acs.jafc.8b07023. Epub 2019 Mar 1. J Agric Food Chem. 2020. PMID: 30799616 Free article.

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Polyphenols bind to low density lipoprotein at biologically relevant concentrations that are protective for heart disease.

Tung WC, Rizzo B, Dabbagh Y, Saraswat S, Romanczyk M, Codorniu-Hernández E, Rebollido-Rios R, Needs PW, Kroon PA, Rakotomanomana N, Dangles O, Weikel K, Vinson J. Tung WC, et al. Among authors: needs pw. Arch Biochem Biophys. 2020 Nov 15;694:108589. doi: 10.1016/j.abb.2020.108589. Epub 2020 Sep 30. Arch Biochem Biophys. 2020. PMID: 33010229

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Hydrophobic Interactions Drive Binding between Vascular Endothelial Growth Factor-A (VEGFA) and Polyphenolic Inhibitors.

Perez-Moral N, Needs PW, Moyle CWA, Kroon PA. Perez-Moral N, et al. Among authors: needs pw. Molecules. 2019 Jul 31;24(15):2785. doi: 10.3390/molecules24152785. Molecules. 2019. PMID: 31370204 Free PMC article.

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Monomeric Flavanols Are More Efficient Substrates for Gut Microbiota Conversion to Hydroxyphenyl-γ-Valerolactone Metabolites Than Oligomeric Procyanidins: A Randomized, Placebo-Controlled Human Intervention Trial.

Hollands WJ, Philo M, Perez-Moral N, Needs PW, Savva GM, Kroon PA. Hollands WJ, et al. Among authors: needs pw. Mol Nutr Food Res. 2020 May;64(10):e1901135. doi: 10.1002/mnfr.201901135. Epub 2020 Apr 20. Mol Nutr Food Res. 2020. PMID: 32223044 Free PMC article. Clinical Trial.

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Inhibitory Effects of Quercetin and Its Human and Microbial Metabolites on Xanthine Oxidase Enzyme.

Mohos V, Pánovics A, Fliszár-Nyúl E, Schilli G, Hetényi C, Mladěnka P, Needs PW, Kroon PA, Pethő G, Poór M. Mohos V, et al. Among authors: needs pw. Int J Mol Sci. 2019 May 31;20(11):2681. doi: 10.3390/ijms20112681. Int J Mol Sci. 2019. PMID: 31159151 Free PMC article.

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