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GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton.
Wolf C, Pouya A, Bitar S, Pfeiffer A, Bueno D, Rojas-Charry L, Arndt S, Gomez-Zepeda D, Tenzer S, Bello FD, Vianello C, Ritz S, Schwirz J, Dobrindt K, Peitz M, Hanschmann EM, Mencke P, Boussaad I, Silies M, Brüstle O, Giacomello M, Krüger R, Methner A. Wolf C, et al. Among authors: mencke p. Commun Biol. 2022 Jun 3;5(1):541. doi: 10.1038/s42003-022-03487-6. Commun Biol. 2022. PMID: 35662277 Free PMC article.