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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1951 1
1966 1
1968 1
1969 3
1970 1
1976 2
1977 1
1978 1
1979 1
1980 1
1981 2
1982 1
1984 1
1985 3
1986 2
1987 2
1988 1
1989 2
1990 2
1991 2
1992 3
1993 6
1994 6
1995 3
1996 4
1997 8
1998 9
1999 10
2000 6
2001 6
2002 10
2003 13
2004 10
2005 14
2006 10
2007 22
2008 9
2009 14
2010 9
2011 17
2012 14
2013 21
2014 32
2015 31
2016 34
2017 41
2018 36
2019 23
2020 11
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419 results
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Page 1
Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease.
Eikelboom JW, Connolly SJ, Bosch J, Dagenais GR, Hart RG, Shestakovska O, Diaz R, Alings M, Lonn EM, Anand SS, Widimsky P, Hori M, Avezum A, Piegas LS, Branch KRH, Probstfield J, Bhatt DL, Zhu J, Liang Y, Maggioni AP, Lopez-Jaramillo P, O'Donnell M, Kakkar AK, Fox KAA, Parkhomenko AN, Ertl G, Störk S, Keltai M, Ryden L, Pogosova N, Dans AL, Lanas F, Commerford PJ, Torp-Pedersen C, Guzik TJ, Verhamme PB, Vinereanu D, Kim JH, Tonkin AM, Lewis BS, Felix C, Yusoff K, Steg PG, Metsarinne KP, Cook Bruns N, Misselwitz F, Chen E, Leong D, Yusuf S; COMPASS Investigators. Eikelboom JW, et al. N Engl J Med. 2017 Oct 5;377(14):1319-1330. doi: 10.1056/NEJMoa1709118. Epub 2017 Aug 27. N Engl J Med. 2017. PMID: 28844192 Free article. Clinical Trial.
Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators. Salloway S, et al. N Engl J Med. 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839. N Engl J Med. 2014. PMID: 24450891 Free PMC article. Clinical Trial.
BACKGROUND: Bapineuzumab, a humanized anti-amyloid-beta monoclonal antibody, is in clinical development for the treatment of Alzheimer's disease. ...CONCLUSIONS: Bapineuzumab did not improve clinical outcomes in patients with Alzheimer's disease, despite treatment d …
BACKGROUND: Bapineuzumab, a humanized anti-amyloid-beta monoclonal antibody, is in clinical development for the treatment of Alzheimer's
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain.
Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, Peter CJ, C W JT, Safaie BM, Morishita H, Roussos P, Nestler EJ, Schaefer A, Tycko B, Brennand KJ, Yagi T, Shen L, Akbarian S. Jiang Y, et al. Nat Genet. 2017 Aug;49(8):1239-1250. doi: 10.1038/ng.3906. Epub 2017 Jul 3. Nat Genet. 2017. PMID: 28671686 Free PMC article.
We show that the SETDB1 repressor complex, which involves multiple KRAB zinc finger proteins, shields neuronal genomes from excess CTCF binding and is critically required for structural maintenance of TAD(cPcdh)....
We show that the SETDB1 repressor complex, which involves multiple KRAB zinc finger proteins, shields neuronal genomes from excess CT …
MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome.
Stavropoulou V, Kaspar S, Brault L, Sanders MA, Juge S, Morettini S, Tzankov A, Iacovino M, Lau IJ, Milne TA, Royo H, Kyba M, Valk PJM, Peters AHFM, Schwaller J. Stavropoulou V, et al. Cancer Cell. 2016 Jul 11;30(1):43-58. doi: 10.1016/j.ccell.2016.05.011. Epub 2016 Jun 23. Cancer Cell. 2016. PMID: 27344946 Free article.
The ribosomal A-site finger is crucial for binding and activation of the stringent factor RelA.
Kudrin P, Dzhygyr I, Ishiguro K, Beljantseva J, Maksimova E, Oliveira SRA, Varik V, Payoe R, Konevega AL, Tenson T, Suzuki T, Hauryliuk V. Kudrin P, et al. Nucleic Acids Res. 2018 Feb 28;46(4):1973-1983. doi: 10.1093/nar/gky023. Nucleic Acids Res. 2018. PMID: 29390134 Free PMC article.
Using a panel of ribosomal RNA mutants, we show that the A-site finger structural element of 23S rRNA helix 38 is crucial for RelA binding to the ribosome and consequent activation, and deletion of the element severely compromises (p)ppGpp accumulation in E. coli upon amin …
Using a panel of ribosomal RNA mutants, we show that the A-site finger structural element of 23S rRNA helix 38 is crucial for RelA bi …
Higher-order oligomerization promotes localization of SPOP to liquid nuclear speckles.
Marzahn MR, Marada S, Lee J, Nourse A, Kenrick S, Zhao H, Ben-Nissan G, Kolaitis RM, Peters JL, Pounds S, Errington WJ, Privé GG, Taylor JP, Sharon M, Schuck P, Ogden SK, Mittag T. Marzahn MR, et al. EMBO J. 2016 Jun 15;35(12):1254-75. doi: 10.15252/embj.201593169. Epub 2016 May 23. EMBO J. 2016. PMID: 27220849 Free PMC article.
Contact mechanics between the human finger and a touchscreen under electroadhesion.
Ayyildiz M, Scaraggi M, Sirin O, Basdogan C, Persson BNJ. Ayyildiz M, et al. Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12668-12673. doi: 10.1073/pnas.1811750115. Epub 2018 Nov 27. Proc Natl Acad Sci U S A. 2018. PMID: 30482858 Free PMC article.
Among these, surface haptic displays that modulate the friction between the human finger and touch surface are emerging as user interfaces. ...We present experimental results on how the friction between a finger and a touchscreen depends on the electrostatic attract …
Among these, surface haptic displays that modulate the friction between the human finger and touch surface are emerging as user inter …
Conversion Discriminative Analysis on Mild Cognitive Impairment Using Multiple Cortical Features from MR Images.
Guo S, Lai C, Wu C, Cen G; Alzheimer's Disease Neuroimaging Initiative. Guo S, et al. Front Aging Neurosci. 2017 May 18;9:146. doi: 10.3389/fnagi.2017.00146. eCollection 2017. Front Aging Neurosci. 2017. PMID: 28572766 Free PMC article.
In this study, 158 subjects (72 NC, 46 sMCI, and 40 cMCI) were selected from the Alzheimer's Disease Neuroimaging Initiative. ...The feasibility of the cortical features for the recognition of anatomical patterns was certified; thus, the proposed method has the potential t …
In this study, 158 subjects (72 NC, 46 sMCI, and 40 cMCI) were selected from the Alzheimer's Disease Neuroimaging Initiative. ...The …
Podocyte-Specific Induction of Krüppel-Like Factor 15 Restores Differentiation Markers and Attenuates Kidney Injury in Proteinuric Kidney Disease.
Guo Y, Pace J, Li Z, Ma'ayan A, Wang Z, Revelo MP, Chen E, Gu X, Attalah A, Yang Y, Estrada C, Yang VW, He JC, Mallipattu SK. Guo Y, et al. J Am Soc Nephrol. 2018 Oct;29(10):2529-2545. doi: 10.1681/ASN.2018030324. Epub 2018 Aug 24. J Am Soc Nephrol. 2018. PMID: 30143559 Free PMC article.
BACKGROUND: Podocyte injury is the hallmark of proteinuric kidney diseases, such as FSGS and minimal change disease, and destabilization of the podocyte's actin cytoskeleton contributes to podocyte dysfunction in many of these conditions. ...We previously showed that loss …
BACKGROUND: Podocyte injury is the hallmark of proteinuric kidney diseases, such as FSGS and minimal change disease, and destabilization of …
CREBBP mutations in individuals without Rubinstein-Taybi syndrome phenotype.
Menke LA, van Belzen MJ, Alders M, Cristofoli F; DDD Study, Ehmke N, Fergelot P, Foster A, Gerkes EH, Hoffer MJ, Horn D, Kant SG, Lacombe D, Leon E, Maas SM, Melis D, Muto V, Park SM, Peeters H, Peters DJ, Pfundt R, van Ravenswaaij-Arts CM, Tartaglia M, Hennekam RC. Menke LA, et al. Am J Med Genet A. 2016 Oct;170(10):2681-93. doi: 10.1002/ajmg.a.37800. Epub 2016 Jun 17. Am J Med Genet A. 2016. PMID: 27311832
No functional studies have (yet) been performed, but we hypothesize that the mutations disturb protein-protein interactions by altering zinc finger function. ...
No functional studies have (yet) been performed, but we hypothesize that the mutations disturb protein-protein interactions by altering zinc …
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