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Did you mean peter johnston (252 results)?
Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1.
Staniszewska AD, Pilger D, Gill SJ, Jamal K, Bohin N, Guzzetti S, Gordon J, Hamm G, Mundin G, Illuzzi G, Pike A, McWilliams L, Maglennon G, Rose J, Hawthorne G, Cortes Gonzalez M, Halldin C, Johnström P, Schou M, Critchlow SE, Fawell S, Johannes JW, Leo E, Davies BR, Cosulich S, Sarkaria JN, O'Connor MJ, Hamerlik P. Staniszewska AD, et al. Among authors: johnstrom p. Clin Cancer Res. 2024 Apr 1;30(7):1338-1351. doi: 10.1158/1078-0432.CCR-23-2094. Clin Cancer Res. 2024. PMID: 37967136
Preclinical Comparison of the Blood-brain barrier Permeability of Osimertinib with Other EGFR TKIs.
Colclough N, Chen K, Johnström P, Strittmatter N, Yan Y, Wrigley GL, Schou M, Goodwin R, Varnäs K, Adua SJ, Zhao M, Nguyen DX, Maglennon G, Barton P, Atkinson J, Zhang L, Janefeldt A, Wilson J, Smith A, Takano A, Arakawa R, Kondrashov M, Malmquist J, Revunov E, Vazquez-Romero A, Moein MM, Windhorst AD, Karp NA, Finlay MRV, Ward RA, Yates JWT, Smith PD, Farde L, Cheng Z, Cross DAE. Colclough N, et al. Among authors: johnstrom p. Clin Cancer Res. 2021 Jan 1;27(1):189-201. doi: 10.1158/1078-0432.CCR-19-1871. Epub 2020 Oct 7. Clin Cancer Res. 2021. PMID: 33028591
Preclinical Comparison of Osimertinib with Other EGFR-TKIs in EGFR-Mutant NSCLC Brain Metastases Models, and Early Evidence of Clinical Brain Metastases Activity.
Ballard P, Yates JW, Yang Z, Kim DW, Yang JC, Cantarini M, Pickup K, Jordan A, Hickey M, Grist M, Box M, Johnström P, Varnäs K, Malmquist J, Thress KS, Jänne PA, Cross D. Ballard P, et al. Among authors: johnstrom p. Clin Cancer Res. 2016 Oct 15;22(20):5130-5140. doi: 10.1158/1078-0432.CCR-16-0399. Epub 2016 Jul 19. Clin Cancer Res. 2016. PMID: 27435396
AZ14289671 is a highly selective and blood-brain barrier penetrant irreversible TKI that targets EGFRExon20 insertions.
Swaih AM, Talbot S, Savoca A, Thorpe H, Flemington V, Phillips B, Colclough N, McCoull W, Radeva V, Hargreaves D, Packer MJ, Felisberto-Rodrigues C, Thomson C, Orme JP, Deane C, Smith A, Johnström P, Schou M, McWilliams L, Davey P, Enget M, O'Neill D, Cosulich S, Floc'h N. Swaih AM, et al. Among authors: johnstrom p. Cell Rep Med. 2025 Sep 16;6(9):102305. doi: 10.1016/j.xcrm.2025.102305. Epub 2025 Aug 25. Cell Rep Med. 2025. PMID: 40858103 Free PMC article.
Subtype-selective positron emission tomography imaging of poly ADP-ribose polymerase-1 binding in non-human primates, healthy volunteers, and patients with glioblastoma using [11C]AZ14193391.
Cselényi Z, Jucaite A, Stragliotto G, Bartek J, Johnström P, Pike A, Cortés González MA, Högnäsbacka A, Dahl K, Ghosh A, Johannes JW, Staniszewska AD, Leo E, Hamerlik P, Davies B, Cosulich S, Swales J, Lawrence R, Squatrito M, Mueller NK, Khani Y, Sousa VC, Stenkrona P, Halldin C, Farde L, Schou M. Cselényi Z, et al. Among authors: johnstrom p. Neuro Oncol. 2026 Mar 1;28(3):802-814. doi: 10.1093/neuonc/noaf290. Neuro Oncol. 2026. PMID: 41437644
Glia Imaging Differentiates Multiple System Atrophy from Parkinson's Disease: A Positron Emission Tomography Study with [11 C]PBR28 and Machine Learning Analysis.
Jucaite A, Cselényi Z, Kreisl WC, Rabiner EA, Varrone A, Carson RE, Rinne JO, Savage A, Schou M, Johnström P, Svenningsson P, Rascol O, Meissner WG, Barone P, Seppi K, Kaufmann H, Wenning GK, Poewe W, Farde L. Jucaite A, et al. Among authors: johnstrom p. Mov Disord. 2022 Jan;37(1):119-129. doi: 10.1002/mds.28814. Epub 2021 Oct 5. Mov Disord. 2022. PMID: 34609758
Optimization of Potent, Efficacious, Selective and Blood-Brain Barrier Penetrating Inhibitors Targeting EGFR Exon20 Insertion Mutations.
Thomson C, Braybrooke E, Colclough N, Davies NL, Floc'h N, Greenwood R, Guérot C, Hargreaves D, Johnstrom P, Khurana P, Kostomiris DH, Li S, Lister A, Lorthioir O, Martin S, McCoull W, McLean NJ, McWilliams L, Orme JP, Packer MJ, Pearson S, Swaih AM, Tentarelli S, Tucker MJ, Ward RA, Wilkinson S, Winlow P, Wood IL. Thomson C, et al. Among authors: johnstrom p. J Med Chem. 2024 Sep 28. doi: 10.1021/acs.jmedchem.4c01792. Online ahead of print. J Med Chem. 2024. PMID: 39340451
In Vivo Visualization of β-Cells by Targeting of GPR44.
Eriksson O, Johnström P, Cselenyi Z, Jahan M, Selvaraju RK, Jensen-Waern M, Takano A, Sörhede Winzell M, Halldin C, Skrtic S, Korsgren O. Eriksson O, et al. Among authors: johnstrom p. Diabetes. 2018 Feb;67(2):182-192. doi: 10.2337/db17-0764. Epub 2017 Dec 5. Diabetes. 2018. PMID: 29208633
Highly Optimized CNS Penetrant Inhibitors of EGFR Exon20 Insertion Mutations.
McCoull W, Thomson C, Braybrooke E, Chan C, Colclough N, Cortés González MA, Cosulich S, Davies NL, Floc'h N, Greenwood R, Hargreaves D, Huang P, Hunt TA, Johnson T, Johnström P, Kettle JG, Kondrashov M, Kostomiris DH, Li S, Lister A, Martin S, McKerrecher D, McLean N, Nissink JWM, Orme JP, Orwig P, Packer MJ, Pearson S, Qin L, Felisberto-Rodrigues C, Savoca A, Schou M, Stokes S, Swaih AM, Talbot S, Tucker MJ, Ward RA, Wadforth E, Wang C, Wilson J, Yang Y. McCoull W, et al. Among authors: johnstrom p. J Med Chem. 2025 Feb 13;68(3):3700-3748. doi: 10.1021/acs.jmedchem.4c02811. Epub 2025 Jan 27. J Med Chem. 2025. PMID: 39869768
55 results