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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
2004 1
2005 1
2006 3
2008 3
2009 4
2010 2
2011 1
2012 3
2013 2
2014 4
2015 5
2016 6
2017 5
2018 3
2019 5
2020 7
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51 results
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Page 1
Direct targeting of Gαq and Gα11 oncoproteins in cancer cells.
Annala S, Feng X, Shridhar N, Eryilmaz F, Patt J, Yang J, Pfeil EM, Cervantes-Villagrana RD, Inoue A, Häberlein F, Slodczyk T, Reher R, Kehraus S, Monteleone S, Schrage R, Heycke N, Rick U, Engel S, Pfeifer A, Kolb P, König G, Bünemann M, Tüting T, Vázquez-Prado J, Gutkind JS, Gaffal E, Kostenis E. Annala S, et al. Among authors: kolb p. Sci Signal. 2019 Mar 19;12(573):eaau5948. doi: 10.1126/scisignal.aau5948. Sci Signal. 2019. PMID: 30890659
Guava (Psidium guajava) Fruit Extract Prepared by Supercritical CO2 Extraction Inhibits Intestinal Glucose Resorption in a Double-Blind, Randomized Clinical Study.
König A, Schwarzinger B, Stadlbauer V, Lanzerstorfer P, Iken M, Schwarzinger C, Kolb P, Schwarzinger S, Mörwald K, Brunner S, Höglinger O, Weghuber D, Weghuber J. König A, et al. Among authors: kolb p. Nutrients. 2019 Jul 3;11(7):1512. doi: 10.3390/nu11071512. Nutrients. 2019. PMID: 31277259 Free PMC article. Clinical Trial.
Comparative Docking to Distinct G Protein-Coupled Receptor Conformations Exclusively Yields Ligands with Agonist Efficacy.
Scharf MM, Bünemann M, Baker JG, Kolb P. Scharf MM, et al. Among authors: kolb p. Mol Pharmacol. 2019 Dec;96(6):851-861. doi: 10.1124/mol.119.117515. Epub 2019 Oct 17. Mol Pharmacol. 2019. PMID: 31624135
Nanobody-Enabled Reverse Pharmacology on G-Protein-Coupled Receptors.
Pardon E, Betti C, Laeremans T, Chevillard F, Guillemyn K, Kolb P, Ballet S, Steyaert J. Pardon E, et al. Among authors: kolb p. Angew Chem Int Ed Engl. 2018 May 4;57(19):5292-5295. doi: 10.1002/anie.201712581. Epub 2018 Mar 30. Angew Chem Int Ed Engl. 2018. PMID: 29469969
Virtual Compound Libraries in Computer-Assisted Drug Discovery.
van Hilten N, Chevillard F, Kolb P. van Hilten N, et al. Among authors: kolb p. J Chem Inf Model. 2019 Feb 25;59(2):644-651. doi: 10.1021/acs.jcim.8b00737. Epub 2019 Jan 24. J Chem Inf Model. 2019. PMID: 30624918
An open source pharma roadmap.
Balasegaram M, Kolb P, McKew J, Menon J, Olliaro P, Sablinski T, Thomas Z, Todd MH, Torreele E, Wilbanks J. Balasegaram M, et al. Among authors: kolb p. PLoS Med. 2017 Apr 18;14(4):e1002276. doi: 10.1371/journal.pmed.1002276. eCollection 2017 Apr. PLoS Med. 2017. PMID: 28419094 Free PMC article.
Drugging specific conformational states of GPCRs: challenges and opportunities for computational chemistry.
Martí-Solano M, Schmidt D, Kolb P, Selent J. Martí-Solano M, et al. Among authors: kolb p. Drug Discov Today. 2016 Apr;21(4):625-31. doi: 10.1016/j.drudis.2016.01.009. Epub 2016 Jan 25. Drug Discov Today. 2016. PMID: 26821135 Review.
Binding-Site Compatible Fragment Growing Applied to the Design of β2-Adrenergic Receptor Ligands.
Chevillard F, Rimmer H, Betti C, Pardon E, Ballet S, van Hilten N, Steyaert J, Diederich WE, Kolb P. Chevillard F, et al. Among authors: kolb p. J Med Chem. 2018 Feb 8;61(3):1118-1129. doi: 10.1021/acs.jmedchem.7b01558. Epub 2018 Jan 24. J Med Chem. 2018. PMID: 29364664
Three stories on Eph kinase inhibitors: From in silico discovery to in vivo validation.
Unzue A, Lafleur K, Zhao H, Zhou T, Dong J, Kolb P, Liebl J, Zahler S, Caflisch A, Nevado C. Unzue A, et al. Among authors: kolb p. Eur J Med Chem. 2016 Apr 13;112:347-366. doi: 10.1016/j.ejmech.2016.01.057. Epub 2016 Feb 2. Eur J Med Chem. 2016. PMID: 26907157 Review.
GPCRmd uncovers the dynamics of the 3D-GPCRome.
Rodríguez-Espigares I, Torrens-Fontanals M, Tiemann JKS, Aranda-García D, Ramírez-Anguita JM, Stepniewski TM, Worp N, Varela-Rial A, Morales-Pastor A, Medel-Lacruz B, Pándy-Szekeres G, Mayol E, Giorgino T, Carlsson J, Deupi X, Filipek S, Filizola M, Gómez-Tamayo JC, Gonzalez A, Gutiérrez-de-Terán H, Jiménez-Rosés M, Jespers W, Kapla J, Khelashvili G, Kolb P, Latek D, Marti-Solano M, Matricon P, Matsoukas MT, Miszta P, Olivella M, Perez-Benito L, Provasi D, Ríos S, R Torrecillas I, Sallander J, Sztyler A, Vasile S, Weinstein H, Zachariae U, Hildebrand PW, De Fabritiis G, Sanz F, Gloriam DE, Cordomi A, Guixà-González R, Selent J. Rodríguez-Espigares I, et al. Among authors: kolb p. Nat Methods. 2020 Aug;17(8):777-787. doi: 10.1038/s41592-020-0884-y. Epub 2020 Jul 13. Nat Methods. 2020. PMID: 32661425
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