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Mitapivat in adults with non-transfusion-dependent α-thalassaemia or β-thalassaemia (ENERGIZE): a phase 3, international, randomised, double-blind, placebo-controlled trial.
Taher AT, Al-Samkari H, Aydinok Y, Besser M, Boscoe AN, Dahlin JL, De Luna G, Estepp JH, Gheuens S, Gilroy KS, Glenthøj A, Sim Goh A, Iyer V, Kattamis A, Loggetto SR, Morris S, Musallam KM, Osman K, Ricchi P, Salido-Fiérrez E, Sheth S, Tai F, Tevich H, Uhlig K, Urbstonaitis R, Viprakasit V, Cappellini MD, Kuo KHM; ENERGIZE investigators. Taher AT, et al. Lancet. 2025 Jul 5;406(10498):33-42. doi: 10.1016/S0140-6736(25)00635-X. Epub 2025 Jun 19. Lancet. 2025. PMID: 40544857 Clinical Trial.
Narsoplimab for refractory transplantation-associated thrombotic microangiopathy (TA-TMA) in adult patients receiving allogeneic hematopoietic stem cell transplantation (AHSCT).
Chumnumsiriwath P, Vittayawacharin P, Ramos-Perez J, Jeyakumar D, Lee BJ, Doh J, Griffin S, Nguyen M, Hanna RM, Tran MH, Kongtim P, Ciurea SO. Chumnumsiriwath P, et al. Bone Marrow Transplant. 2025 Jul;60(7):1065-1069. doi: 10.1038/s41409-025-02595-1. Epub 2025 Apr 22. Bone Marrow Transplant. 2025. PMID: 40263635 Free PMC article. No abstract available.
Venetoclax combined with cladribine, idarubicin, cytarabine (CLIA-VEN) results in higher remission rates over conventional 7 + 3 chemotherapy without increased toxicity in newly diagnosed acute myeloid leukaemia.
Lee BJ, Griffin SP, Doh J, Quach A, Sun Y, Chumnumsiriwath P, Ciurea SO, Ramos-Perez J, Bellman P, Jeyakumar D, Kongtim P, Naqvi K. Lee BJ, et al. Among authors: chumnumsiriwath p. Br J Haematol. 2026 Feb;208(2):570-578. doi: 10.1111/bjh.70253. Epub 2025 Nov 12. Br J Haematol. 2026. PMID: 41224356 Free PMC article.
Clinical characteristics, laboratory features and genetic profile of hemoglobin E (HBB:c.79 G > A)/β (nucleotide -28 A > G) (HBB:c.-78 A > G) -thalassemia subjects identified from community- and hospital-recruited cohorts.
Chumnumsiriwath P, Charoenporn P, Jermnim S, Suannum P, Samaisombat M, Tapprom A, Deoisares R, Wong P. Chumnumsiriwath P, et al. Blood Cells Mol Dis. 2024 Nov;109:102883. doi: 10.1016/j.bcmd.2024.102883. Epub 2024 Aug 8. Blood Cells Mol Dis. 2024. PMID: 39154456
Essential genetic modifiers and their measurable impact in a community-recruited population analysis for non-severe hemoglobin E/β-thalassemia prenatal genetic counseling.
Wong P, Chitsobhak T, Jittasathian S, Sirichantharawat C, Cherdchoo N, Prangcharoen W, Jongautchariyakul P, Jampachaisri K, Tapprom A, Deoisares R, Chumnumsiriwath P. Wong P, et al. Among authors: chumnumsiriwath p. Blood Cells Mol Dis. 2023 Nov;103:102765. doi: 10.1016/j.bcmd.2023.102765. Epub 2023 Jun 15. Blood Cells Mol Dis. 2023. PMID: 37353362
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