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Year Number of Results
2010 1
2011 1
2019 4
2020 2
2021 0
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8 results
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Page 1
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target.
Yuan S, Chu H, Chan JF, Ye ZW, Wen L, Yan B, Lai PM, Tee KM, Huang J, Chen D, Li C, Zhao X, Yang D, Chiu MC, Yip C, Poon VK, Chan CC, Sze KH, Zhou J, Chan IH, Kok KH, To KK, Kao RY, Lau JY, Jin DY, Perlman S, Yuen KY. Yuan S, et al. Among authors: lai pm. Nat Commun. 2019 Jan 10;10(1):120. doi: 10.1038/s41467-018-08015-x. Nat Commun. 2019. PMID: 30631056 Free PMC article.
Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication.
Yan B, Chu H, Yang D, Sze KH, Lai PM, Yuan S, Shuai H, Wang Y, Kao RY, Chan JF, Yuen KY. Yan B, et al. Among authors: lai pm. Viruses. 2019 Jan 16;11(1):73. doi: 10.3390/v11010073. Viruses. 2019. PMID: 30654597 Free PMC article.
Lipidomic Profiling Reveals Significant Perturbations of Intracellular Lipid Homeostasis in Enterovirus-Infected Cells.
Yan B, Zou Z, Chu H, Chan G, Tsang JO, Lai PM, Yuan S, Yip CC, Yin F, Kao RY, Sze KH, Lau SK, Chan JF, Yuen KY. Yan B, et al. Among authors: lai pm. Int J Mol Sci. 2019 Nov 26;20(23):5952. doi: 10.3390/ijms20235952. Int J Mol Sci. 2019. PMID: 31779252 Free PMC article.
Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target.
Yuan S, Chu H, Huang J, Zhao X, Ye ZW, Lai PM, Wen L, Cai JP, Mo Y, Cao J, Liang R, Poon VK, Sze KH, Zhou J, To KK, Chen Z, Chen H, Jin DY, Chan JF, Yuen KY. Yuan S, et al. Among authors: lai pm. Sci Adv. 2020 Aug 28;6(35):eaba7910. doi: 10.1126/sciadv.aba7910. eCollection 2020 Aug. Sci Adv. 2020. PMID: 32923629 Free PMC article.
Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters.
Yuan S, Yin X, Meng X, Chan J, Ye ZW, Riva L, Pache L, Chan CC, Lai PM, Chan C, Poon V, Matsunaga N, Pu Y, Yuen CK, Cao J, Liang R, Tang K, Sheng L, Du Y, Xu W, Sze KH, Zhang J, Chu H, Kok KH, To K, Jin DY, Sun R, Chanda S, Yuen KY. Yuan S, et al. Among authors: lai pm. Res Sq. 2020 Oct 7:rs.3.rs-86169. doi: 10.21203/rs.3.rs-86169/v1. Preprint. Res Sq. 2020. PMID: 33052331 Free PMC article.
Talaromyces marneffei Mp1 Protein, a Novel Virulence Factor, Carries Two Arachidonic Acid-Binding Domains To Suppress Inflammatory Responses in Hosts.
Lam WH, Sze KH, Ke Y, Tse MK, Zhang H, Woo PCY, Lau SKP, Lau CCY, Xu S, Lai PM, Zhou T, Antonyuk SV, Kao RYT, Yuen KY, Hao Q. Lam WH, et al. Among authors: lai pm. Infect Immun. 2019 Mar 25;87(4):e00679-18. doi: 10.1128/IAI.00679-18. Print 2019 Apr. Infect Immun. 2019. PMID: 30670555 Free PMC article.
Probing protein dynamics by nuclear magnetic resonance.
Sze KH, Lai PM. Sze KH, et al. Among authors: lai pm. Protein Pept Lett. 2011 Apr;18(4):373-9. doi: 10.2174/092986611794653897. Protein Pept Lett. 2011. PMID: 21222637 Review.
Identification of a nonaketide product for the iterative polyketide synthase in biosynthesis of the nine-membered enediyne C-1027.
Chen X, Guo ZF, Lai PM, Sze KH, Guo Z. Chen X, et al. Among authors: lai pm. Angew Chem Int Ed Engl. 2010 Oct 18;49(43):7926-8. doi: 10.1002/anie.201003369. Angew Chem Int Ed Engl. 2010. PMID: 20848627 No abstract available.
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