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Recombinant Live Attenuated Influenza Vaccine Viruses Carrying Conserved T-cell Epitopes of Human Adenoviruses Induce Functional Cytotoxic T-Cell Responses and Protect Mice against Both Infections.
Isakova-Sivak I, Matyushenko V, Stepanova E, Matushkina A, Kotomina T, Mezhenskaya D, Prokopenko P, Kudryavtsev I, Kopeykin P, Sivak K, Rudenko L. Isakova-Sivak I, et al. Among authors: prokopenko p. Vaccines (Basel). 2020 Apr 24;8(2):196. doi: 10.3390/vaccines8020196. Vaccines (Basel). 2020. PMID: 32344618 Free PMC article.
Conserved T-cell epitopes of respiratory syncytial virus (RSV) delivered by recombinant live attenuated influenza vaccine viruses efficiently induce RSV-specific lung-localized memory T cells and augment influenza-specific resident memory T-cell responses.
Matyushenko V, Kotomina T, Kudryavtsev I, Mezhenskaya D, Prokopenko P, Matushkina A, Sivak K, Muzhikyan A, Rudenko L, Isakova-Sivak I. Matyushenko V, et al. Among authors: prokopenko p. Antiviral Res. 2020 Oct;182:104864. doi: 10.1016/j.antiviral.2020.104864. Epub 2020 Jun 22. Antiviral Res. 2020. PMID: 32585323 Free PMC article.
Live attenuated influenza vaccine viral vector induces functional cytotoxic T-cell immune response against foreign CD8+ T-cell epitopes inserted into NA and NS1 genes using the 2A self-cleavage site.
Kotomina T, Korenkov D, Matyushenko V, Prokopenko P, Rudenko L, Isakova-Sivak I. Kotomina T, et al. Among authors: prokopenko p. Hum Vaccin Immunother. 2018;14(12):2964-2970. doi: 10.1080/21645515.2018.1502529. Epub 2018 Aug 29. Hum Vaccin Immunother. 2018. PMID: 30024831 Free PMC article.