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Endogenous T Cell Receptor Rearrangement Represses Aggressive Central Nervous System Autoimmunity in a TcR-Transgenic Model on the Non-Obese Diabetic Background.
Yeola AP, Ignatius Arokia Doss PM, Baillargeon J, Akbar I, Mailhot B, Balood M, Talbot S, Anderson AC, Lacroix S, Rangachari M. Yeola AP, et al. Among authors: ignatius arokia doss pm. Front Immunol. 2020 Jan 15;10:3115. doi: 10.3389/fimmu.2019.03115. eCollection 2019. Front Immunol. 2020. PMID: 32010149 Free PMC article.
IL-1β enables CNS access to CCR2hi monocytes and the generation of pathogenic cells through GM-CSF released by CNS endothelial cells.
Paré A, Mailhot B, Lévesque SA, Juzwik C, Ignatius Arokia Doss PM, Lécuyer MA, Prat A, Rangachari M, Fournier A, Lacroix S. Paré A, et al. Among authors: ignatius arokia doss pm. Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):E1194-E1203. doi: 10.1073/pnas.1714948115. Epub 2018 Jan 22. Proc Natl Acad Sci U S A. 2018. PMID: 29358392 Free PMC article.
Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity.
Doss PMIA, Umair M, Baillargeon J, Fazazi R, Fudge N, Akbar I, Yeola AP, Williams JB, Leclercq M, Joly-Beauparlant C, Beauchemin P, Ruda GF, Alpaugh M, Anderson AC, Brennan PE, Droit A, Lassmann H, Moore CS, Rangachari M. Doss PMIA, et al. Cell Rep. 2021 Mar 9;34(10):108833. doi: 10.1016/j.celrep.2021.108833. Cell Rep. 2021. PMID: 33691111 Free article.