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Pembrolizumab Plus mFOLFOX7 or FOLFIRI for Microsatellite Stable/Mismatch Repair-Proficient Metastatic Colorectal Cancer: KEYNOTE-651 Cohorts B and D.
Kim R, Tehfe M, Kavan P, Chaves J, Kortmansky JS, Chen EX, Lieu CH, Wong L, Fakih M, Spencer K, Zhao Q, Predoiu R, Li C, Leconte P, Adelberg D, Chiorean EG. Kim R, et al. Clin Colorectal Cancer. 2024 Jun;23(2):118-127.e6. doi: 10.1016/j.clcc.2024.03.001. Epub 2024 Apr 1. Clin Colorectal Cancer. 2024. PMID: 38762348 Clinical Trial.
One dose-limiting toxicity (grade 3 small intestine obstruction) occurred in cohort D. In cohort B, grade 3 or 4 treatment-related adverse events (AEs) occurred in 18 patients (58%), most commonly neutropenia and decreased neutrophil count (n = 5 each). ...No grade 5 treat …
One dose-limiting toxicity (grade 3 small intestine obstruction) occurred in cohort D. In cohort B, grade 3 or 4 treatment-related ad …
Antimicrobial and physical properties of experimental endodontic sealers containing vegetable extracts.
Dos Santos DC, da Silva Barboza A, Schneider LR, Cuevas-Suárez CE, Ribeiro JS, Damian MF, Campos AD, Lund RG. Dos Santos DC, et al. Sci Rep. 2021 Mar 19;11(1):6450. doi: 10.1038/s41598-021-85609-4. Sci Rep. 2021. PMID: 33742040 Free PMC article.
The physical properties were not influenced by the addition of the vegetable extracts (p > 0.05). For S. mutans, only T. minuta and B. orellana groups presented antibacterial activity after 24 h of contact (p < 0.05). ...
The physical properties were not influenced by the addition of the vegetable extracts (p > 0.05). For S. mutans, only T. minuta and B …
Impact of shelf-life simulation on bonding performance of universal adhesive systems.
Cuevas-Suárez CE, Ramos TS, Rodrigues SB, Collares FM, Zanchi CH, Lund RG, da Silva AF, Piva E. Cuevas-Suárez CE, et al. Dent Mater. 2019 Sep;35(9):e204-e219. doi: 10.1016/j.dental.2019.05.023. Epub 2019 Jun 19. Dent Mater. 2019. PMID: 31227184
METHODS: Five universal adhesives (Single Bond Universal, SBU; Tetric Bond Universal, TBU; OneCoat Universal, OCU; OptiBond Universal, OBU; and Prime&Bond Elect, P&B), two two-step self-etch adhesives (Clearfil SE, CSE; and AdheSE, ASE) and one two-step etch-and-ri …
METHODS: Five universal adhesives (Single Bond Universal, SBU; Tetric Bond Universal, TBU; OneCoat Universal, OCU; OptiBond Universal, OBU; …
Correlation of Trichosporon asahii Genotypes with Anatomical Sites and Antifungal Susceptibility Profiles: Data Analyses from 284 Isolates Collected in the Last 22 Years across 24 Medical Centers.
Francisco EC, de Almeida Junior JN, Queiroz-Telles F, Aquino VR, Mendes AVA, de Oliveira Silva M, Castro PTOE, Guimarães T, Ponzio V, Hahn RC, Chaves GM, Colombo AL. Francisco EC, et al. Antimicrob Agents Chemother. 2021 Feb 17;65(3):e01104-20. doi: 10.1128/AAC.01104-20. Print 2021 Feb 17. Antimicrob Agents Chemother. 2021. PMID: 33318016 Free PMC article.
Species identification and genotype characterization were performed by analysis of the intergenic spacer (IGS1) region of the ribosomal DNA (rDNA). Antifungal susceptibility testing (AST) for amphotericin B and azoles was with the CLSI M27, 4th edition, microdilution broth …
Species identification and genotype characterization were performed by analysis of the intergenic spacer (IGS1) region of the ribosomal DNA …
Species distribution and antifungal susceptibility of 358 Trichosporon clinical isolates collected in 24 medical centres.
Francisco EC, de Almeida Junior JN, de Queiroz Telles F, Aquino VR, Mendes AVA, de Andrade Barberino MGM, de Tarso O Castro P, Guimarães T, Hahn RC, Padovan ACB, Chaves GM, Colombo AL. Francisco EC, et al. Clin Microbiol Infect. 2019 Jul;25(7):909.e1-909.e5. doi: 10.1016/j.cmi.2019.03.026. Epub 2019 Apr 13. Clin Microbiol Infect. 2019. PMID: 30991116 Free article.
METHODS: Species identification was performed by sequencing the IGS1 region of rDNA. Antifungal susceptibility testing for amphotericin B, fluconazole, voriconazole and posaconazole followed the Clinical and Laboratory Standards Institute reference method. ...The ECV for a …
METHODS: Species identification was performed by sequencing the IGS1 region of rDNA. Antifungal susceptibility testing for amphotericin B …
Pembrolizumab Plus Binimetinib With or Without Chemotherapy for MSS/pMMR Metastatic Colorectal Cancer: Outcomes From KEYNOTE-651 Cohorts A, C, and E.
Chen EX, Kavan P, Tehfe M, Kortmansky JS, Sawyer MB, Chiorean EG, Lieu CH, Polite B, Wong L, Fakih M, Spencer K, Chaves J, Li C, Leconte P, Adelberg D, Kim R. Chen EX, et al. Clin Colorectal Cancer. 2024 Jun;23(2):183-193. doi: 10.1016/j.clcc.2024.03.002. Epub 2024 Apr 1. Clin Colorectal Cancer. 2024. PMID: 38653648 Clinical Trial.