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Synthetic GPCRs for programmable sensing and control of cell behaviour.
Kalogriopoulos NA, Tei R, Yan Y, Klein PM, Ravalin M, Cai B, Soltesz I, Li Y, Ting AY. Kalogriopoulos NA, et al. Among authors: ravalin m. Nature. 2025 Jan;637(8044):230-239. doi: 10.1038/s41586-024-08282-3. Epub 2024 Dec 4. Nature. 2025. PMID: 39633047 Free PMC article.
End-Binding E3 Ubiquitin Ligases Enable Protease Signaling.
Ravalin M, Basu K, Gestwicki JE, Craik CS. Ravalin M, et al. ACS Chem Biol. 2021 Nov 19;16(11):2047-2056. doi: 10.1021/acschembio.9b00621. Epub 2019 Nov 20. ACS Chem Biol. 2021. PMID: 31714737 Free PMC article. Review.
Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases.
Ravalin M, Theofilas P, Basu K, Opoku-Nsiah KA, Assimon VA, Medina-Cleghorn D, Chen YF, Bohn MF, Arkin M, Grinberg LT, Craik CS, Gestwicki JE. Ravalin M, et al. Nat Chem Biol. 2019 Aug;15(8):786-794. doi: 10.1038/s41589-019-0322-6. Epub 2019 Jul 18. Nat Chem Biol. 2019. PMID: 31320752 Free PMC article.
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