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128 results
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Filters applied: . Clear all The following term was not found in PubMed: Davidrajuh
Page 1
Reggie/flotillin and the targeted delivery of cargo.
Stuermer CA. Stuermer CA. J Neurochem. 2011 Mar;116(5):708-13. doi: 10.1111/j.1471-4159.2010.07007.x. Epub 2011 Jan 7. J Neurochem. 2011. PMID: 21214550 Free article. Review.
The two proteins reggie-1/flotillin-2 and reggie-2/flotillin-1 form microdomains at the plasma membrane and at intracellular compartments where src tyrosine kinases associate with them. Specific GPI-anchored proteins, in particular prion protein and Thy-1, co-cluste …
The two proteins reggie-1/flotillin-2 and reggie-2/flotillin-1 form microdomains at the plasma membrane and at intracellular c …
Reggie-1/Flotillin-2 regulates integrin trafficking and focal adhesion turnover via Rab11a.
Hülsbusch N, Solis GP, Katanaev VL, Stuermer CA. Hülsbusch N, et al. Eur J Cell Biol. 2015 Nov;94(11):531-45. doi: 10.1016/j.ejcb.2015.07.003. Epub 2015 Jul 31. Eur J Cell Biol. 2015. PMID: 26299802
Here we demonstrate a function of reggies in focal adhesion (FA) formation and alpha5- and beta1-integrin recycling to FAs. ...Wild type and constitutively-active (CA) Rab11a rescued the phenotype (normal number of FAs) whereas dominant-negative (DN) Rab11a mimicked the lo …
Here we demonstrate a function of reggies in focal adhesion (FA) formation and alpha5- and beta1-integrin recycling to FAs. ...Wild t …
Dissecting the molecular function of reggie/flotillin proteins.
Babuke T, Tikkanen R. Babuke T, et al. Eur J Cell Biol. 2007 Sep;86(9):525-32. doi: 10.1016/j.ejcb.2007.03.003. Epub 2007 May 4. Eur J Cell Biol. 2007. PMID: 17482313 Review.
Reggie-1/flotillin-2 and reggie-2/flotillin-1 are ubiquitously expressed, well-conserved proteins that are associated with membrane microdomains known as rafts. ...In this review, we will focus on some recent findings that have shed new light on the elusive molecula
Reggie-1/flotillin-2 and reggie-2/flotillin-1 are ubiquitously expressed, well-conserved proteins that are associated with mem
The reggie/flotillin connection to growth.
Stuermer CA. Stuermer CA. Trends Cell Biol. 2010 Jan;20(1):6-13. doi: 10.1016/j.tcb.2009.10.003. Epub 2009 Nov 5. Trends Cell Biol. 2010. PMID: 19896850
The proteins reggie-1 and reggie-2 were originally discovered in neurons during axon regeneration. ...Recent results now show that reggie/flotillin proteins are indeed necessary for axon regeneration and growth: no axons form when reggies/flotillins ar …
The proteins reggie-1 and reggie-2 were originally discovered in neurons during axon regeneration. ...Recent results now show …
Reggie/flotillin proteins are organized into stable tetramers in membrane microdomains.
Solis GP, Hoegg M, Munderloh C, Schrock Y, Malaga-Trillo E, Rivera-Milla E, Stuermer CA. Solis GP, et al. Biochem J. 2007 Apr 15;403(2):313-22. doi: 10.1042/BJ20061686. Biochem J. 2007. PMID: 17206938 Free PMC article.
Furthermore, since depletion of reggie-1 by siRNA (small interfering RNA) silencing induces proteasomal degradation of reggie-2, we conclude that the protein stability of reggie-2 depends on the presence of reggie-1. Our data indicate that the basic st …
Furthermore, since depletion of reggie-1 by siRNA (small interfering RNA) silencing induces proteasomal degradation of reggie- …
Hetero-oligomerization of reggie-1/flotillin-2 and reggie-2/flotillin-1 is required for their endocytosis.
Babuke T, Ruonala M, Meister M, Amaddii M, Genzler C, Esposito A, Tikkanen R. Babuke T, et al. Cell Signal. 2009 Aug;21(8):1287-97. doi: 10.1016/j.cellsig.2009.03.012. Epub 2009 Mar 24. Cell Signal. 2009. PMID: 19318123
Here we have analyzed the mechanism of the EGF-stimulated endocytosis of reggies in more detail and show that the Src-mediated phosphorylation of reggie-1 is not the driving force for endocytosis. However, hetero-oligomerization with reggie-2 is necessary for …
Here we have analyzed the mechanism of the EGF-stimulated endocytosis of reggies in more detail and show that the Src-mediated phosph …
Scaffolding microdomains and beyond: the function of reggie/flotillin proteins.
Langhorst MF, Reuter A, Stuermer CA. Langhorst MF, et al. Cell Mol Life Sci. 2005 Oct;62(19-20):2228-40. doi: 10.1007/s00018-005-5166-4. Cell Mol Life Sci. 2005. PMID: 16091845 Review.
Reggie/flotillin proteins are considered to be components of lipid rafts and are commonly used as marker proteins for lipid microdomains. Yet almost a decade after their discovery, the function of reggies/ flotillins is still enigmatic. In this review we summarize t
Reggie/flotillin proteins are considered to be components of lipid rafts and are commonly used as marker proteins for lipid microdoma
Functional aspects of membrane association of reggie/flotillin proteins.
Banning A, Tomasovic A, Tikkanen R. Banning A, et al. Curr Protein Pept Sci. 2011 Dec;12(8):725-35. doi: 10.2174/138920311798841708. Curr Protein Pept Sci. 2011. PMID: 22329548 Review.
Flotillin-2 and flotillin-1, also called reggie-1 and reggie-2, are ubiquitously expressed and highly conserved proteins. ...
Flotillin-2 and flotillin-1, also called reggie-1 and reggie-2, are ubiquitously expressed and highly conserved proteins. ...
Trafficking of the microdomain scaffolding protein reggie-1/flotillin-2.
Langhorst MF, Reuter A, Jaeger FA, Wippich FM, Luxenhofer G, Plattner H, Stuermer CA. Langhorst MF, et al. Eur J Cell Biol. 2008 Apr;87(4):211-26. doi: 10.1016/j.ejcb.2007.12.001. Epub 2008 Jan 30. Eur J Cell Biol. 2008. PMID: 18237819
Besides their localization at the plasma membrane, the reggies/flotillins reside at various intracellular compartments; however, the trafficking pathways used by reggie-1/flotillin-2 remain unclear. ...Reggie-2/flotillin-1 and stomatin-1 also exhibited cyclin …
Besides their localization at the plasma membrane, the reggies/flotillins reside at various intracellular compartments; however, the …
Cellular roles of the prion protein in association with reggie/flotillin microdomains.
Solis GP, Malaga-Trillo E, Plattner H, Stuermer CA. Solis GP, et al. Front Biosci (Landmark Ed). 2010 Jun 1;15:1075-85. doi: 10.2741/3662. Front Biosci (Landmark Ed). 2010. PMID: 20515742 Free article. Review.
Here we review these data and discuss how the spatial link between PrP and the microdomain-forming proteins reggie-1 (flotillin-2) and reggie-2 (flotillin-1) may contribute to PrP signaling, leading to the local assembly of membrane protein complexes at sites involv …
Here we review these data and discuss how the spatial link between PrP and the microdomain-forming proteins reggie-1 (flotillin-2) an …
128 results