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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1949 1
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1957 1
1960 2
1961 3
1965 2
1966 8
1967 10
1968 24
1969 42
1970 44
1971 74
1972 96
1973 112
1974 171
1975 232
1976 225
1977 236
1978 211
1979 288
1980 316
1981 435
1982 453
1983 642
1984 805
1985 1047
1986 1279
1987 1859
1988 2616
1989 3660
1990 4658
1991 5680
1992 6763
1993 8075
1994 9470
1995 10706
1996 11668
1997 12446
1998 13252
1999 14313
2000 15619
2001 16758
2002 17307
2003 17639
2004 19149
2005 19380
2006 18665
2007 19311
2008 19797
2009 19629
2010 20715
2011 22332
2012 23665
2013 24921
2014 24575
2015 24354
2016 24062
2017 23748
2018 23115
2019 23336
2020 24470
2021 24296
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2023 18255
2024 20893
2025 23218
2026 1469

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606,843 results

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Page 1
Showing results for gene binding
Search for René Bindig instead (1 results)
The eIF2alpha/ATF4 pathway is essential for stress-induced autophagy gene expression.
B'chir W, Maurin AC, Carraro V, Averous J, Jousse C, Muranishi Y, Parry L, Stepien G, Fafournoux P, Bruhat A. B'chir W, et al. Nucleic Acids Res. 2013 Sep;41(16):7683-99. doi: 10.1093/nar/gkt563. Epub 2013 Jun 26. Nucleic Acids Res. 2013. PMID: 23804767 Free PMC article.
In response to different environmental stresses, eIF2alpha phosphorylation represses global translation coincident with preferential translation of ATF4, a master regulator controlling the transcription of key genes essential for adaptative functions. Here, we establish th …
In response to different environmental stresses, eIF2alpha phosphorylation represses global translation coincident with preferential transla …
Differential Contributions of DNA-Binding Proteins to Polycomb Response Element Activity at the Drosophila giant Gene.
Ghotbi E, Lackey K, Wong V, Thompson KT, Caston EG, Haddadi M, Benes J, Jones RS. Ghotbi E, et al. Genetics. 2020 Mar;214(3):623-634. doi: 10.1534/genetics.119.302981. Epub 2020 Jan 9. Genetics. 2020. PMID: 31919108 Free PMC article.
During early embryonic development, Pho binds to PRE1 30-min prior to stable binding to PRE2. This observation indicated a possible dependence of PRE2 on PRE1 for PcG recruitment; however, we find here that PRE2 recruits PcG proteins and maintains transcriptional re …
During early embryonic development, Pho binds to PRE1 30-min prior to stable binding to PRE2. This observation indicated a pos …
Interaction of methyl-CpG-binding protein 2 (MeCP2) with distinct enhancers in the mouse cortex.
Mishra GP, Sun EX, Chin T, Eckhardt M, Greenberg ME, Stroud H. Mishra GP, et al. Nat Neurosci. 2025 Jan;28(1):62-71. doi: 10.1038/s41593-024-01808-y. Epub 2024 Nov 22. Nat Neurosci. 2025. PMID: 39578572
Mutations in methyl-CpG-binding protein 2 (MeCP2) cause Rett syndrome. MeCP2 is thought to regulate gene transcription by binding to methylated DNA broadly across the genome. Here, using cleavage under target and release under nuclease (CUT&RUN) assays in …
Mutations in methyl-CpG-binding protein 2 (MeCP2) cause Rett syndrome. MeCP2 is thought to regulate gene transcription by b
CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytes.
Christy RJ, Kaestner KH, Geiman DE, Lane MD. Christy RJ, et al. Proc Natl Acad Sci U S A. 1991 Mar 15;88(6):2593-7. doi: 10.1073/pnas.88.6.2593. Proc Natl Acad Sci U S A. 1991. PMID: 2006196 Free PMC article.
DNase I cleavage-inhibition patterns (footprinting) of the C/EBP gene promoter by nuclear factors from differentiated and undifferentiated 3T3-L1 cells identified two sites of differential factor binding. One site in the C/EBP gene promoter between nucleotide …
DNase I cleavage-inhibition patterns (footprinting) of the C/EBP gene promoter by nuclear factors from differentiated and undifferent …
Min3: Predict microRNA target gene using an improved binding-site representation method and support vector machine.
Huang T, Huang X, Yao M. Huang T, et al. J Bioinform Comput Biol. 2019 Oct;17(5):1950032. doi: 10.1142/S021972001950032X. J Bioinform Comput Biol. 2019. PMID: 31856668
MicroRNAs are single-stranded noncoding RNAs known to down-regulate target genes at the protein or mRNA level. Computational prediction of targets is essential for elucidating the detailed functions of microRNA. However, prediction specificity and sensitivity of the existi …
MicroRNAs are single-stranded noncoding RNAs known to down-regulate target genes at the protein or mRNA level. Computational predicti …
Regulation of the immunoglobulin gene transcription.
Lefranc G, Lefranc MP. Lefranc G, et al. Biochimie. 1990 Jan;72(1):7-17. doi: 10.1016/0300-9084(90)90167-f. Biochimie. 1990. PMID: 2111179 Review.
The transcription of the immunoglobulin heavy (IGH), kappa (IGK) and lambda (IGL) chain genes is coordinate and B lymphocyte specific. This expression of the immunoglobulin genes is under the control of regulatory elements: the promoters located 5' of each variable …
The transcription of the immunoglobulin heavy (IGH), kappa (IGK) and lambda (IGL) chain genes is coordinate and B lymphocyte specific …
Proteins binding to the liver-specific pyruvate kinase gene promoter. A unique combination of known factors.
Vaulont S, Puzenat N, Levrat F, Cognet M, Kahn A, Raymondjean M. Vaulont S, et al. J Mol Biol. 1989 Sep 20;209(2):205-19. doi: 10.1016/0022-2836(89)90273-8. J Mol Biol. 1989. PMID: 2585483
A 183 base-pair fragment of the liver-specific promoter of the L-type puruvate kinase (L-PK) gene has been shown by transfection assay to be sufficient to confer a tissue-specific expression to a reporter gene. ...They were called, from 3' to 5', L1 to L4 binding
A 183 base-pair fragment of the liver-specific promoter of the L-type puruvate kinase (L-PK) gene has been shown by transfection assa …
Differential binding of erythroid Krupple-like factor to embryonic/fetal globin gene promoters during development.
Zhou D, Pawlik KM, Ren J, Sun CW, Townes TM. Zhou D, et al. J Biol Chem. 2006 Jun 9;281(23):16052-7. doi: 10.1074/jbc.M601182200. Epub 2006 Apr 10. J Biol Chem. 2006. PMID: 16606611 Free article.
The competition model for beta-like globin gene switching during development predicts that differential binding of transcription factors to globin gene promoters and/or proximal enhancers regulate the competitive interactions of globin gene family memb …
The competition model for beta-like globin gene switching during development predicts that differential binding of transcripti …
Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility.
Lenardo M, Pierce JW, Baltimore D. Lenardo M, et al. Science. 1987 Jun 19;236(4808):1573-7. doi: 10.1126/science.3109035. Science. 1987. PMID: 3109035
Individual protein-binding sites within the mouse immunoglobulin heavy chain and kappa light chain gene enhancers were altered, making it possible to examine the functional role of the sites during transcription. ...The only known heavy chain enhancer site that b
Individual protein-binding sites within the mouse immunoglobulin heavy chain and kappa light chain gene enhancers were altered …
Binding, sliding, and function of cohesin during transcriptional activation.
Borrie MS, Campor JS, Joshi H, Gartenberg MR. Borrie MS, et al. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1062-E1071. doi: 10.1073/pnas.1617309114. Epub 2017 Jan 30. Proc Natl Acad Sci U S A. 2017. PMID: 28137853 Free PMC article.
In the yeast Saccharomyces cerevisiae, the complex binds discrete sites along chromosomes, including positions within and around genes. Transcriptional activity redistributes the complex to the 3' ends of convergently oriented gene pairs. Despite the wealth o …
In the yeast Saccharomyces cerevisiae, the complex binds discrete sites along chromosomes, including positions within and around g
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