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Covalent inhibition of pro-apoptotic BAX.
McHenry MW, Shi P, Camara CM, Cohen DT, Rettenmaier TJ, Adhikary U, Gygi MA, Yang K, Gygi SP, Wales TE, Engen JR, Wells JA, Walensky LD. McHenry MW, et al. Among authors: rettenmaier tj. Nat Chem Biol. 2024 Jan 17. doi: 10.1038/s41589-023-01537-6. Online ahead of print. Nat Chem Biol. 2024. PMID: 38233584
Redox priming promotes Aurora A activation during mitosis.
Lim DC, Joukov V, Rettenmaier TJ, Kumagai A, Dunphy WG, Wells JA, Yaffe MB. Lim DC, et al. Among authors: rettenmaier tj. Sci Signal. 2020 Jul 21;13(641):eabb6707. doi: 10.1126/scisignal.abb6707. Sci Signal. 2020. PMID: 32694171 Free PMC article.
Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering.
Harvey EP, Hauseman ZJ, Cohen DT, Rettenmaier TJ, Lee S, Huhn AJ, Wales TE, Seo HS, Luccarelli J, Newman CE, Guerra RM, Bird GH, Dhe-Paganon S, Engen JR, Wells JA, Walensky LD. Harvey EP, et al. Among authors: rettenmaier tj. Cell Chem Biol. 2020 Jun 18;27(6):647-656.e6. doi: 10.1016/j.chembiol.2020.04.004. Epub 2020 May 14. Cell Chem Biol. 2020. PMID: 32413285 Free PMC article.