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Biosynthesis of Largimycins in Streptomyces argillaceus Involves Transient β-Alkylation and Cryptic Halogenation Steps Unprecedented in the Leinamycin Family.
ACS Chem Biol. 2022 Aug 19;17(8):2320-2331. doi: 10.1021/acschembio.2c00416. Epub 2022 Jul 13.
ACS Chem Biol. 2022.
PMID: 35830174
Free PMC article.
Largimycins A1 and A2 are key members of a recently identified family of hybrid nonribosomal peptide polyketides belonging to the scarcely represented group of antitumor leinamycins. ...This cluster contains a halogenase gene and two sets of genes for the biosynthesis and …
Largimycins A1 and A2 are key members of a recently identified family of hybrid nonribosomal peptide polyketides belonging to the sca …
5-Alkylresorcinol Derivatives from the Bryozoan Schizomavella mamillata: Isolation, Synthesis, and Antioxidant Activity.
Ortega MJ, Pantoja JJ, de Los Reyes C, Zubía E.
Ortega MJ, et al.
Mar Drugs. 2017 Nov 2;15(11):344. doi: 10.3390/md15110344.
Mar Drugs. 2017.
PMID: 29099074
Free PMC article.
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Infliximab in ulcerative colitis: real-life analysis of factors predicting treatment discontinuation due to lack of response or colectomy: ECIA (ACAD Colitis and Infliximab Study).
Fernández-Salazar L, Muñoz F, Barrio J, Muñoz C, Pajares R, Rivero M, Prieto V, Legido J, Bouhmidi A, Herranz M, Fernández N, Sánchez-Ocaña R, Joao D, Santos F.
Fernández-Salazar L, et al.
Scand J Gastroenterol. 2016;51(2):186-95. doi: 10.3109/00365521.2015.1070900. Epub 2015 Jul 22.
Scand J Gastroenterol. 2016.
PMID: 26200929
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