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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1950 3
1951 4
1954 2
1955 2
1956 3
1958 1
1960 1
1962 1
1964 1
1965 3
1966 7
1967 3
1968 4
1969 4
1970 7
1971 6
1972 3
1973 5
1974 5
1975 3
1977 3
1978 1
1979 2
1980 3
1981 3
1982 3
1983 4
1984 2
1985 2
1986 3
1987 11
1988 10
1989 14
1990 16
1991 9
1992 19
1993 12
1994 28
1995 15
1996 15
1997 23
1998 54
1999 80
2000 70
2001 70
2002 98
2003 107
2004 113
2005 160
2006 176
2007 171
2008 147
2009 152
2010 151
2011 197
2012 207
2013 226
2014 311
2015 380
2016 419
2017 481
2018 633
2019 679
2020 841
2021 1043
2022 1093
2023 1214
2024 415

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8,775 results

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The following term was not found in PubMed: 20Keuneke
Page 1
Rita Levi-Montalcini: the neurologist who challenged fascism.
Coutinho L, Teive HAG. Coutinho L, et al. Arq Neuropsiquiatr. 2023 Jan;81(1):95-98. doi: 10.1055/s-0043-1761426. Epub 2023 Mar 14. Arq Neuropsiquiatr. 2023. PMID: 36918012 Free PMC article. Review.
Rita Levi-Montalcini was a researcher in the field of neuroscience, Italian and Jewish in origin, who discovered the nerve growth factor and rightfully earned the 1986 Nobel Prize in Physiology or Medicine, alongside her collaborator Stanley Cohen. ...Despite these obstacl …
Rita Levi-Montalcini was a researcher in the field of neuroscience, Italian and Jewish in origin, who discovered the nerve growth fac …
Why Are We Scientists? Drawing Inspiration From Rita Levi-Montalcini.
Malerba F. Malerba F. Front Cell Neurosci. 2022 Jan 21;15:741984. doi: 10.3389/fncel.2021.741984. eCollection 2021. Front Cell Neurosci. 2022. PMID: 35126056 Free PMC article. Review.
In 2007, drawing inspiration from her previous experiments on chick embryos, Rita Levi-Montalcini, at the age of 98, proposed a new project, and a research group, in which I was included, was formed at the European Brain Research Institute (EBRI). ...This approach has alwa …
In 2007, drawing inspiration from her previous experiments on chick embryos, Rita Levi-Montalcini, at the age of 98, proposed a new p …
Chk2 mediates RITA-induced apoptosis.
de Lange J, Verlaan-de Vries M, Teunisse AF, Jochemsen AG. de Lange J, et al. Cell Death Differ. 2012 Jun;19(6):980-9. doi: 10.1038/cdd.2011.182. Epub 2011 Dec 9. Cell Death Differ. 2012. PMID: 22158418 Free PMC article.
In addition, we observed an early p53- and Chk2-dependent block of DNA replication upon RITA treatment. Replicating cells seemed more prone to entering RITA-induced apoptosis. ...In conclusion, we identified Chk2 as an essential mediator of the cellular responses to …
In addition, we observed an early p53- and Chk2-dependent block of DNA replication upon RITA treatment. Replicating cells seemed more …
RITA outcomes.
Jones E. Jones E. Br Dent J. 2006 Mar 25;200(6):303. doi: 10.1038/sj.bdj.4813379. Br Dent J. 2006. PMID: 16568036 No abstract available.
RITA modulates cell migration and invasion by affecting focal adhesion dynamics.
Hoock SC, Ritter A, Steinhäuser K, Roth S, Behrends C, Oswald F, Solbach C, Louwen F, Kreis NN, Yuan J. Hoock SC, et al. Mol Oncol. 2019 Oct;13(10):2121-2141. doi: 10.1002/1878-0261.12551. Epub 2019 Aug 6. Mol Oncol. 2019. PMID: 31353815 Free PMC article.
Since RITA interacts with tubulin and coats microtubules of the cytoskeleton, we hypothesized that it is involved in cell motility. We show here that depletion of RITA reduces cell migration and invasion of diverse cancer cell lines and mouse embryonic fibroblasts. …
Since RITA interacts with tubulin and coats microtubules of the cytoskeleton, we hypothesized that it is involved in cell motility. W …
RITA requires eIF2alpha-dependent modulation of mRNA translation for its anti-cancer activity.
Ristau J, van Hoef V, Peuget S, Zhu J, Guan BJ, Liang S, Hatzoglou M, Topisirovic I, Selivanova G, Larsson O. Ristau J, et al. Cell Death Dis. 2019 Nov 7;10(11):845. doi: 10.1038/s41419-019-2074-3. Cell Death Dis. 2019. PMID: 31699971 Free PMC article.
Yet, mechanisms underlying the anticancer activity of RITA are incompletely understood. Here we show that RITA suppresses mRNA translation independently of p53 by inducing eIF2alpha phosphorylation. ...Moreover, inhibition of eIF2alpha phosphorylation attenuates pro …
Yet, mechanisms underlying the anticancer activity of RITA are incompletely understood. Here we show that RITA suppresses mRNA …
[RITA selectively inhibits proliferation of BAP1-deficient cutaneous melanoma cells in vitro].
Shi W, Liu X, Zhang G, Ye L, Zhou R, Li Y, Yu L. Shi W, et al. Nan Fang Yi Ke Da Xue Xue Bao. 2023 May 20;43(5):710-717. doi: 10.12122/j.issn.1673-4254.2023.05.05. Nan Fang Yi Ke Da Xue Xue Bao. 2023. PMID: 37313811 Free PMC article. Chinese.
CONCLUSION: Loss of BAP1 results in the sensitivity of cutaneous melanoma cells to p53 activator RITA. In melanoma cells, the activity of ubiquitinase in BAP1 is directly related to their sensitivity to RITA. An increased expression of p53 protein induced by BAP1 kn …
CONCLUSION: Loss of BAP1 results in the sensitivity of cutaneous melanoma cells to p53 activator RITA. In melanoma cells, the activit …
RITA Is Expressed in Trophoblastic Cells and Is Involved in Differentiation Processes of the Placenta.
Wildner JM, Friemel A, Jennewein L, Roth S, Ritter A, Schüttler C, Chen Q, Louwen F, Yuan J, Kreis NN. Wildner JM, et al. Cells. 2019 Nov 21;8(12):1484. doi: 10.3390/cells8121484. Cells. 2019. PMID: 31766533 Free PMC article.
RITA's messenger RNA (mRNA) level is decreased in primary tissue samples from early-onset PE patients. ...These data suggest that RITA may play important roles in the development of the placenta and possibly in the pathogenesis of PE....
RITA's messenger RNA (mRNA) level is decreased in primary tissue samples from early-onset PE patients. ...These data suggest that …
Looking at the future with Rita.
Bentivoglio M. Bentivoglio M. Neuroscience. 2013 Nov 12;252:438-42. doi: 10.1016/j.neuroscience.2013.08.013. Neuroscience. 2013. PMID: 24288808
This paper on Rita Levi-Montalcini (1909-2012), who received in 1986 the Nobel Prize in Physiology or Medicine for the discovery of nerve growth factor, focuses on aspects of her advocacy and her commitment to education in which she has been especially active in the last p …
This paper on Rita Levi-Montalcini (1909-2012), who received in 1986 the Nobel Prize in Physiology or Medicine for the discovery of n …
RITA Mimics: Synthesis and Mechanistic Evaluation of Asymmetric Linked Trithiazoles.
Pietkiewicz AL, Zhang Y, Rahimi MN, Stramandinoli M, Teusner M, McAlpine SR. Pietkiewicz AL, et al. ACS Med Chem Lett. 2017 Mar 6;8(4):401-406. doi: 10.1021/acsmedchemlett.6b00488. eCollection 2017 Apr 13. ACS Med Chem Lett. 2017. PMID: 28435526 Free PMC article.
The established cytotoxic agent RITA contains a thiophene-furan-thiophene backbone and two terminal alcohol groups. ...Evaluating the impact of 7h on proteins targeted by RITA (p53, c-Myc, and Mcl-1) indicated that it acts via a different mechanism of action to that …
The established cytotoxic agent RITA contains a thiophene-furan-thiophene backbone and two terminal alcohol groups. ...Evaluating the …
8,775 results