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Maintaining Interrater Agreement of Core Assessment Instruments in a Multisite Randomized Controlled Clinical Trial: The Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) Trial.
Lebet R, Hayakawa J, Chamblee TB, Tala JA, Singh N, Wypij D, Curley MAQ. Lebet R, et al. Nurs Res. 2017 Jul/Aug;66(4):323-329. doi: 10.1097/NNR.0000000000000224. Nurs Res. 2017. PMID: 28654569 Free PMC article. Clinical Trial.
There was no difference in Fleiss's kappa for any of the instruments based on unit size or timing of assessment (earlier or later in the study). For SBS scores, Fleiss's kappa was significantly different in larger and smaller PICUs (.82 vs. .92, p = .003); however, …
There was no difference in Fleiss's kappa for any of the instruments based on unit size or timing of assessment (earlier or later in …
Site Variability in Regulatory Oversight for an International Study of Pediatric Sepsis.
Michelson KN, Reubenson G, Weiss SL, Fitzgerald JC, Ackerman KK, Christie L, Bush JL, Nadkarni VM, Thomas NJ, Schreiner MS; Sepsis Prevalence, Outcomes, and Therapy (SPROUT) Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators Network. Michelson KN, et al. Pediatr Crit Care Med. 2018 Apr;19(4):e180-e188. doi: 10.1097/PCC.0000000000001455. Pediatr Crit Care Med. 2018. PMID: 29377867
Enrollment was delayed at eight sites due to prolonged (> 50 d) time to approval. Of 49 U.S. sites, 43% considered using a single institutional review board, but only 18% utilized this option. ...Duplicative review prolonged time to protocol approval at some sites. Use …
Enrollment was delayed at eight sites due to prolonged (> 50 d) time to approval. Of 49 U.S. sites, 43% considered using a single …
Impact of the Magnitude and Timing of Fluid Overload on Outcomes in Critically Ill Children: A Report From the Multicenter International Assessment of Worldwide Acute Kidney Injury, Renal Angina, and Epidemiology (AWARE) Study.
Selewski DT, Gist KM, Basu RK, Goldstein SL, Zappitelli M, Soranno DE, Mammen C, Sutherland SM, Askenazi DJ, Ricci Z, Akcan-Arikan A, Gorga SM, Gillespie SE, Woroniecki R; Assessment of the Worldwide Acute Kidney Injury, Renal Angina and Epidemiology (AWARE) Investigators. Selewski DT, et al. Crit Care Med. 2023 Feb 17:e005791. doi: 10.1097/CCM.0000000000005791. Online ahead of print. Crit Care Med. 2023. PMID: 36821787