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2006 1
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12 results

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Page 1
Effectiveness of pharmacological procedural sedation in children with autism spectrum disorder: A systematic review and meta-analysis.
Zupin L, Sahyoun C, Krauss B, Dagri A, Rocco EM, Barbi E, Celsi F. Zupin L, et al. Acta Paediatr. 2024 Nov;113(11):2363-2377. doi: 10.1111/apa.17364. Epub 2024 Jul 31. Acta Paediatr. 2024. PMID: 39086012
RESULTS: Twenty studies met inclusion criteria. Dexmedetomidine, midazolam, propofol and chloral hydrate were the most efficient agents for successful procedures, while propofol had the highest number of adverse events. The most frequently used agents were dexmedetomidi …
RESULTS: Twenty studies met inclusion criteria. Dexmedetomidine, midazolam, propofol and chloral hydrate were the most efficient agen …
Intraoperative opioid exposure, tumour genomic alterations, and survival differences in people with lung adenocarcinoma.
Connolly JG, Tan KS, Mastrogiacomo B, Dycoco J, Caso R, Jones GD, McCormick PJ, Sanchez-Vega F, Irie T, Scarpa JR, Gupta HV, Adusumilli PS, Rocco G, Isbell JM, Bott MJ, Fischer GW, Jones DR, Mincer JS. Connolly JG, et al. Br J Anaesth. 2021 Jul;127(1):75-84. doi: 10.1016/j.bja.2021.03.030. Br J Anaesth. 2021. PMID: 34147159 Free PMC article.
We sought to determine whether intraoperative opioid exposure is associated with recurrence-specific survival and overall survival in early-stage lung adenocarcinoma, and whether selected tumour genomics are associated with this relationship. Associations between ketamine and …
We sought to determine whether intraoperative opioid exposure is associated with recurrence-specific survival and overall survival in early- …
Dexmedetomidine Sedation After Tracheal Surgery: A Prospective Pilot Study.
Fiorelli S, Creazzola F, Massullo D, Defraia V, Maggi L, Rocco M, Rendina EA. Fiorelli S, et al. Ann Thorac Surg. 2019 Jul;108(1):256-261. doi: 10.1016/j.athoracsur.2019.01.047. Epub 2019 Mar 1. Ann Thorac Surg. 2019. PMID: 30831108
The mean arterial pressure (MAP) and heart rate (HR) were significantly decreased during dexmedetomidine infusion (baseline MAP 90.29 14.33 mm Hg versus 18-hour MAP 82.50 15.44 mm Hg; baseline HR 81.50 12.76 beats/min versus 18-hour HR 69.29 10.21 beats/min; p < …
The mean arterial pressure (MAP) and heart rate (HR) were significantly decreased during dexmedetomidine infusion (baseline MAP 90.29 …
Dexmedetomidine compared to low-dose ketamine better protected not only the brain but also the lungs in acute ischemic stroke.
Heil LBB, Braga CL, Magalhães RF, Antunes MA, Cruz FF, Samary CS, Battaglini D, Robba C, Pelosi P, Silva PL, Rocco PRM. Heil LBB, et al. Int Immunopharmacol. 2023 Nov;124(Pt B):111004. doi: 10.1016/j.intimp.2023.111004. Epub 2023 Sep 29. Int Immunopharmacol. 2023. PMID: 37778171
BACKGROUND: Dexmedetomidine (DEX) and low-dose ketamine (KET) present neuroprotective effects in acute ischemic stroke (AIS); however, to date, no studies have evaluated which has better protective effects not only on the brain but also lungs in AIS. ...CONCLUSIONS: In the …
BACKGROUND: Dexmedetomidine (DEX) and low-dose ketamine (KET) present neuroprotective effects in acute ischemic stroke (AIS); however …
Mild hypothermia combined with dexmedetomidine reduced brain, lung, and kidney damage in experimental acute focal ischemic stroke.
Battaglini D, da Silva AL, Felix NS, Rodrigues G, Antunes MA, Rocha NN, Capelozzi VL, Morales MM, Cruz FF, Robba C, Silva PL, Pelosi P, Rocco PRM. Battaglini D, et al. Intensive Care Med Exp. 2022 Dec 19;10(1):53. doi: 10.1186/s40635-022-00481-4. Intensive Care Med Exp. 2022. PMID: 36529842 Free PMC article.
In lungs: (1) hypothermia + propofol compared to normothermia + propofol reduced TNF-alpha and histologic injury score; (2) hypothermia + dexmedetomidine compared to normothermia + dexmedetomidine reduced histologic injury score. In kidneys: (1) hypothermia + dex …
In lungs: (1) hypothermia + propofol compared to normothermia + propofol reduced TNF-alpha and histologic injury score; (2) hypothermia + …
Year in review in Intensive Care Medicine 2012: III. Noninvasive ventilation, monitoring and patient-ventilator interactions, acute respiratory distress syndrome, sedation, paediatrics and miscellanea.
Antonelli M, Bonten M, Cecconi M, Chastre J, Citerio G, Conti G, Curtis JR, Hedenstierna G, Joannidis M, Macrae D, Maggiore SM, Mancebo J, Mebazaa A, Preiser JC, Rocco P, Timsit JF, Wernerman J, Zhang H. Antonelli M, et al. Intensive Care Med. 2013 Apr;39(4):543-57. doi: 10.1007/s00134-012-2807-6. Epub 2013 Jan 22. Intensive Care Med. 2013. PMID: 23338570 Free PMC article. Review. No abstract available.
Effects of dexmedetomidine on respiratory mechanics and control of breathing in normal rats.
Fernandes FC, Ferreira HC, Cagido VR, Carvalho GM, Pereira LS, Faffe DS, Zin WA, Rocco PR. Fernandes FC, et al. Respir Physiol Neurobiol. 2006 Dec;154(3):342-50. doi: 10.1016/j.resp.2006.02.002. Epub 2006 Mar 9. Respir Physiol Neurobiol. 2006. PMID: 16527548
Dexmedetomidine is a highly selective and specific alpha(2)-adrenergic agonist, with sedative, analgesic, and sympatholytic activities. ...The rats of the DMED group received dexmedetomidine (250mugkg(-1) i.p. followed by intravenous infusion of 0.5mugkg(-1)h(-1)). …
Dexmedetomidine is a highly selective and specific alpha(2)-adrenergic agonist, with sedative, analgesic, and sympatholytic activitie …
Comparative effects of dexmedetomidine and propofol on brain and lung damage in experimental acute ischemic stroke.
Sousa GC, Fernandes MV, Cruz FF, Antunes MA, da Silva CM, Takyia C, Battaglini D, Samary CS, Robba C, Pelosi P, Rocco PRM, Silva PL. Sousa GC, et al. Sci Rep. 2021 Nov 30;11(1):23133. doi: 10.1038/s41598-021-02608-1. Sci Rep. 2021. PMID: 34848804 Free PMC article.
Acute ischemic stroke is associated with pulmonary complications, and often dexmedetomidine and propofol are used to decrease cerebral metabolic rate. However, it is unknown the immunomodulatory actions of dexmedetomidine and propofol on brain and lungs during acute …
Acute ischemic stroke is associated with pulmonary complications, and often dexmedetomidine and propofol are used to decrease cerebra …
Effects of short-term propofol and dexmedetomidine on pulmonary morphofunction and biological markers in experimental mild acute lung injury.
Cavalcanti V, Santos CL, Samary CS, Araújo MN, Heil LB, Morales MM, Silva PL, Pelosi P, Fernandes FC, Villela N, Rocco PR. Cavalcanti V, et al. Respir Physiol Neurobiol. 2014 Nov 1;203:45-50. doi: 10.1016/j.resp.2014.08.008. Epub 2014 Aug 19. Respir Physiol Neurobiol. 2014. PMID: 25149586 Free article.
We evaluated whether the short-term use of dexmedetomidine and propofol may attenuate inflammatory response and improve lung morphofunction in experimental acute lung injury (ALI). ...After 24h, ALI animals were randomly treated with dexmedetomidine, propofol, or th …
We evaluated whether the short-term use of dexmedetomidine and propofol may attenuate inflammatory response and improve lung morphofu …
12 results