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Dexmedetomidine Sedation After Tracheal Surgery: A Prospective Pilot Study.
Fiorelli S, Creazzola F, Massullo D, Defraia V, Maggi L, Rocco M, Rendina EA. Fiorelli S, et al. Ann Thorac Surg. 2019 Jul;108(1):256-261. doi: 10.1016/j.athoracsur.2019.01.047. Epub 2019 Mar 1. Ann Thorac Surg. 2019. PMID: 30831108
BACKGROUND: Fourteen adults undergoing tracheal resection and reconstruction surgery were enrolled in this prospective observational pilot study to evaluate dexmedetomidine-based sedation after tracheal surgery in an intensive care unit. ...No cases of delirium were encoun …
BACKGROUND: Fourteen adults undergoing tracheal resection and reconstruction surgery were enrolled in this prospective observational pilot s …
The effect of dexmedetomidine on status epilepticus in a patient with anti-NMDA receptor encephalitis.
Coluzzi F, Angelini A, Simmaco M, Alampi D, Alessandri E, Grassi E, Monina MG, Rocco M. Coluzzi F, et al. Can J Anaesth. 2020 Nov;67(11):1677-1679. doi: 10.1007/s12630-020-01753-x. Epub 2020 Jul 15. Can J Anaesth. 2020. PMID: 32671806 No abstract available.
Year in review in Intensive Care Medicine 2012: III. Noninvasive ventilation, monitoring and patient-ventilator interactions, acute respiratory distress syndrome, sedation, paediatrics and miscellanea.
Antonelli M, Bonten M, Cecconi M, Chastre J, Citerio G, Conti G, Curtis JR, Hedenstierna G, Joannidis M, Macrae D, Maggiore SM, Mancebo J, Mebazaa A, Preiser JC, Rocco P, Timsit JF, Wernerman J, Zhang H. Antonelli M, et al. Intensive Care Med. 2013 Apr;39(4):543-57. doi: 10.1007/s00134-012-2807-6. Epub 2013 Jan 22. Intensive Care Med. 2013. PMID: 23338570 Free PMC article. Review. No abstract available.
The Effects of Short-Term Propofol and Dexmedetomidine on Lung Mechanics, Histology, and Biological Markers in Experimental Obesity.
Heil LB, Santos CL, Santos RS, Samary CS, Cavalcanti VC, Araújo MM, Poggio H, Maia Lde A, Trevenzoli IH, Pelosi P, Fernandes FC, Villela NR, Silva PL, Rocco PR. Heil LB, et al. Anesth Analg. 2016 Apr;122(4):1015-23. doi: 10.1213/ANE.0000000000001114. Anesth Analg. 2016. PMID: 26720616
In a model of diet-induced obesity, we compared the short-term effects of dexmedetomidine versus propofol on lung mechanics and histology, as well as biological markers of inflammation and oxidative stress modulation in obesity. ...However, unlike sodium thiopental and pro …
In a model of diet-induced obesity, we compared the short-term effects of dexmedetomidine versus propofol on lung mechanics and histo …
Effects of short-term propofol and dexmedetomidine on pulmonary morphofunction and biological markers in experimental mild acute lung injury.
Cavalcanti V, Santos CL, Samary CS, Araújo MN, Heil LB, Morales MM, Silva PL, Pelosi P, Fernandes FC, Villela N, Rocco PR. Cavalcanti V, et al. Respir Physiol Neurobiol. 2014 Nov 1;203:45-50. doi: 10.1016/j.resp.2014.08.008. Epub 2014 Aug 19. Respir Physiol Neurobiol. 2014. PMID: 25149586 Free article.
We evaluated whether the short-term use of dexmedetomidine and propofol may attenuate inflammatory response and improve lung morphofunction in experimental acute lung injury (ALI). ...Dexmedetomidine improved oxygenation, but did not modify lung mechanics or histolo …
We evaluated whether the short-term use of dexmedetomidine and propofol may attenuate inflammatory response and improve lung morphofu …
Effects of dexmedetomidine on respiratory mechanics and control of breathing in normal rats.
Fernandes FC, Ferreira HC, Cagido VR, Carvalho GM, Pereira LS, Faffe DS, Zin WA, Rocco PR. Fernandes FC, et al. Respir Physiol Neurobiol. 2006 Dec;154(3):342-50. doi: 10.1016/j.resp.2006.02.002. Epub 2006 Mar 9. Respir Physiol Neurobiol. 2006. PMID: 16527548
Dexmedetomidine is a highly selective and specific alpha(2)-adrenergic agonist, with sedative, analgesic, and sympatholytic activities. ...In spontaneously breathing rats, minute ventilation, respiratory frequency, and neuromuscular inspiratory drive were lower in dexme
Dexmedetomidine is a highly selective and specific alpha(2)-adrenergic agonist, with sedative, analgesic, and sympatholytic activitie
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