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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1948 2
1949 1
1950 7
1951 6
1952 5
1953 7
1954 2
1955 3
1956 6
1957 5
1958 2
1959 2
1963 7
1964 9
1965 5
1966 6
1967 14
1968 22
1969 20
1970 7
1971 2
1972 7
1973 3
1974 2
1975 2
1976 4
1977 3
1978 10
1979 11
1980 4
1981 9
1982 24
1983 25
1984 21
1985 26
1986 25
1987 24
1988 22
1989 23
1990 22
1991 22
1992 19
1993 4
1994 4
1995 6
1996 7
1997 4
1998 12
1999 10
2000 21
2001 18
2002 41
2003 39
2004 30
2005 49
2006 41
2007 34
2008 43
2009 45
2010 70
2011 60
2012 60
2013 44
2014 52
2015 61
2016 56
2017 60
2018 68
2019 70
2020 102
2021 108
2022 81
2023 66
2024 37

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1,722 results

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The following term was not found in PubMed: 20Mandeljc
Page 1
ROK and Arteriolar Myogenic Tone Generation: Molecular Evidence in Health and Disease.
El-Yazbi AF, Abd-Elrahman KS. El-Yazbi AF, et al. Front Pharmacol. 2017 Feb 23;8:87. doi: 10.3389/fphar.2017.00087. eCollection 2017. Front Pharmacol. 2017. PMID: 28280468 Free PMC article. Review.
A highly sensitive biochemical detection approach was beneficial in examining the role of ROK in different force generation mechanisms along the course of myogenic constriction. ...We will also present evidence that alterations in ROK signaling could underlie the pr …
A highly sensitive biochemical detection approach was beneficial in examining the role of ROK in different force generation mechanism …
Rok from B. subtilis: Bridging genome structure and transcription regulation.
Erkelens AM, van Erp B, Meijer WJJ, Dame RT. Erkelens AM, et al. Mol Microbiol. 2024 Mar 21. doi: 10.1111/mmi.15250. Online ahead of print. Mol Microbiol. 2024. PMID: 38511404 Review.
In this review, we provide arguments supporting this view using the Gram-positive bacterium Bacillus subtilis as a model. Proteins BsSMC, HBsu and Rok all impact the structure of the B. subtilis chromosome. Particularly for Rok, there is compelling evidence that it …
In this review, we provide arguments supporting this view using the Gram-positive bacterium Bacillus subtilis as a model. Proteins BsSMC, HB …
The B. subtilis Rok protein is an atypical H-NS-like protein irresponsive to physico-chemical cues.
Erkelens AM, Qin L, van Erp B, Miguel-Arribas A, Abia D, Keek HGJ, Markus D, Cajili MKM, Schwab S, Meijer WJJ, Dame RT. Erkelens AM, et al. Nucleic Acids Res. 2022 Nov 28;50(21):12166-12185. doi: 10.1093/nar/gkac1064. Nucleic Acids Res. 2022. PMID: 36408910 Free PMC article.
Based on this, Rok was proposed to be a functional homolog of E. coli H-NS. However, it is largely unclear how Rok binds DNA, how it represses transcription and whether Rok mediates environment-responsive gene regulation. ...We demonstrate that Rok is …
Based on this, Rok was proposed to be a functional homolog of E. coli H-NS. However, it is largely unclear how Rok binds DNA, …
ROK controls urethral tone, but by what mechanism?
Ratz PH. Ratz PH. Am J Physiol Renal Physiol. 2011 Jan;300(1):F71-2. doi: 10.1152/ajprenal.00608.2010. Epub 2010 Oct 20. Am J Physiol Renal Physiol. 2011. PMID: 20962113 Free article. No abstract available.
Nucleoid-associated Rok differentially affects chromosomal transformation on Bacillus subtilis recombination-deficient cells.
Serrano E, Torres R, Alonso JC. Serrano E, et al. Environ Microbiol. 2021 Jun;23(6):3318-3331. doi: 10.1111/1462-2920.15562. Environ Microbiol. 2021. PMID: 33973337
Rok, a Bacillus subtilis nucleoid-associated protein (NAP), negatively regulates competence development and silences xenogeneic genes. We show that rok inactivation increases rpoB482 natural intraspecies chromosomal transformation (CT) and plasmid transformation to …
Rok, a Bacillus subtilis nucleoid-associated protein (NAP), negatively regulates competence development and silences xenogeneic genes …
Dia- and Rok-dependent enrichment of capping proteins in a cortical region.
Schmidt A, Li L, Lv Z, Yan S, Großhans J. Schmidt A, et al. J Cell Sci. 2021 Nov 1;134(21):jcs258973. doi: 10.1242/jcs.258973. Epub 2021 Nov 5. J Cell Sci. 2021. PMID: 34633047 Free PMC article.
Rho signaling with its major targets the formin Dia, Rho kinase (Rok) and non-muscle myosin II (MyoII, encoded by zip in flies) control turnover, amount and contractility of actomyosin. ...The intercap enrichment of Capping protein was impaired in dia mutants and embryos, …
Rho signaling with its major targets the formin Dia, Rho kinase (Rok) and non-muscle myosin II (MyoII, encoded by zip in flies) contr …
ROK and RSK2-kinase pathways differ between senescent human renal and mesenteric arteries.
Lubomirov LT, Mantke R, Enzmann T, Metzler D, Korotkova T, Hescheler J, Pfitzer G, Grisk O. Lubomirov LT, et al. J Hypertens. 2023 Jul 1;41(7):1201-1214. doi: 10.1097/HJH.0000000000003450. Epub 2023 Apr 27. J Hypertens. 2023. PMID: 37115907
Basal and alpha 1 adrenergic receptor stimulation-induced phosphorylation of the regulatory light chain of myosin (MLC 20 ) was higher in h-RA than in h-MA. This was associated with higher ROK-dependent phosphorylation of the regulatory subunit of myosin light-chain-phosph …
Basal and alpha 1 adrenergic receptor stimulation-induced phosphorylation of the regulatory light chain of myosin (MLC 20 ) was higher in h- …
The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus.
Coombes D, Davies JS, Newton-Vesty MC, Horne CR, Setty TG, Subramanian R, Moir JWB, Friemann R, Panjikar S, Griffin MDW, North RA, Dobson RCJ. Coombes D, et al. J Biol Chem. 2020 Mar 6;295(10):3301-3315. doi: 10.1074/jbc.RA119.010526. Epub 2020 Jan 15. J Biol Chem. 2020. PMID: 31949045 Free PMC article.
Sequence alignments reveal that Gram-positive NanK enzymes belong to the Repressor, ORF, Kinase (ROK) family, but many lack the canonical Zn-binding motif expected for this function, and the sugar-binding EXGH motif is altered to EXGY. ...This characterization provides ins …
Sequence alignments reveal that Gram-positive NanK enzymes belong to the Repressor, ORF, Kinase (ROK) family, but many lack the canon …
How bacterial xenogeneic silencer rok distinguishes foreign from self DNA in its resident genome.
Duan B, Ding P, Hughes TR, Navarre WW, Liu J, Xia B. Duan B, et al. Nucleic Acids Res. 2018 Nov 2;46(19):10514-10529. doi: 10.1093/nar/gky836. Nucleic Acids Res. 2018. PMID: 30252102 Free PMC article.
These structural features endow Rok with preference towards DNA sequences harboring AACTA, TACTA, and flexible multiple TpA steps, while rigid A-tracts are disfavored. Correspondingly, the Bacillus genomes containing Rok are rich in A-tracts and show a dramatic unde …
These structural features endow Rok with preference towards DNA sequences harboring AACTA, TACTA, and flexible multiple TpA steps, wh …
1,722 results