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Page 1
Tapinarof for the treatment of psoriasis.
Nogueira S, Rodrigues MA, Vender R, Torres T. Nogueira S, et al. Dermatol Ther. 2022 Dec;35(12):e15931. doi: 10.1111/dth.15931. Epub 2022 Oct 21. Dermatol Ther. 2022. PMID: 36226669 Free PMC article. Review.
The most commonly used drugs are still vitamin D analogues and corticosteroids, both with several limitations. The aryl hydrocarbon receptor (AhR) plays a role in the pathogenesis of psoriasis, and tapinarof, a novel, first-in-class, small molecule topical therapeutic AhR- …
The most commonly used drugs are still vitamin D analogues and corticosteroids, both with several limitations. The aryl hydrocarbon r …
Rare variant contribution to the heritability of coronary artery disease.
Rocheleau G, Clarke SL, Auguste G, Hasbani NR, Morrison AC, Heath AS, Bielak LF, Iyer KR, Young EP, Stitziel NO, Jun G, Laurie C, Broome JG, Khan AT, Arnett DK, Becker LC, Bis JC, Boerwinkle E, Bowden DW, Carson AP, Ellinor PT, Fornage M, Franceschini N, Freedman BI, Heard-Costa NL, Hou L, Chen YI, Kenny EE, Kooperberg C, Kral BG, Loos RJF, Lutz SM, Manson JE, Martin LW, Mitchell BD, Nassir R, Palmer ND, Post WS, Preuss MH, Psaty BM, Raffield LM, Regan EA, Rich SS, Smith JA, Taylor KD, Yanek LR, Young KA; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Hilliard AT, Tcheandjieu C, Peyser PA, Vasan RS, Rotter JI, Miller CL, Assimes TL, de Vries PS, Do R. Rocheleau G, et al. Nat Commun. 2024 Oct 9;15(1):8741. doi: 10.1038/s41467-024-52939-6. Nat Commun. 2024. PMID: 39384761 Free PMC article.
I-CARE, a European Prospective Cohort Study Assessing Safety and Effectiveness of Biologics in Inflammatory Bowel Disease.
Peyrin-Biroulet L, Rahier JF, Kirchgesner J, Abitbol V, Shaji S, Armuzzi A, Karmiris K, Gisbert JP, Bossuyt P, Helwig U, Burisch J, Yanai H, Doherty GA, Magro F, Molnar T, Löwenberg M, Halfvarson J, Zagorowicz E, Rousseau H, Baumann C, Baert F, Beaugerie L; I-CARE Collaborator Group. Peyrin-Biroulet L, et al. Clin Gastroenterol Hepatol. 2023 Mar;21(3):771-788.e10. doi: 10.1016/j.cgh.2022.09.018. Epub 2022 Sep 22. Clin Gastroenterol Hepatol. 2023. PMID: 36152897 Free article.
Single-cell analysis of neoplastic plasma cells identifies myeloma pathobiology mediators and potential targets.
Moreno Rueda LY, Wang H, Akagi K, Dang M, Vora A, Qin L, Lee HC, Patel KK, Lin P, Mery DE, Zhan F, Shaughnessy JD Jr, Yi Q, Song Y, Jiang B, Gillison ML, Thomas SK, Weber DM, Diao L, Wang J, Kuiatse I, Manasanch EE, Symer DE, Orlowski RZ. Moreno Rueda LY, et al. Cell Rep Med. 2025 Feb 18;6(2):101925. doi: 10.1016/j.xcrm.2024.101925. Epub 2025 Jan 23. Cell Rep Med. 2025. PMID: 39855192 Free PMC article.
Pembrolizumab ± paricalcitol in metastatic pancreatic cancer postmaximal cytoreduction.
Chung V, Alistar A, Becerra C, Kasi A, Borazanci E, Jameson GS, Roe DJ, Wertheim BC, Cridebring D, Truitt M, Downes M, Barrett MT, Korn R, Lee K, Han H, Evans R, Von Hoff DD. Chung V, et al. Oncologist. 2025 Jan 17;30(1):oyae323. doi: 10.1093/oncolo/oyae323. Oncologist. 2025. PMID: 39846984 Free PMC article. Clinical Trial.
BACKGROUND: Immunotherapy has limited benefit in the treatment of advanced pancreatic cancer with the tumor microenvironment playing a key role in immune resistance. In preclinical studies, vitamin D receptor (VDR) agonists have been shown to sensitize pancreatic tumors to …
BACKGROUND: Immunotherapy has limited benefit in the treatment of advanced pancreatic cancer with the tumor microenvironment playing a key r …
Efficacy and safety of CAR T-cell therapy in patients with primary or secondary CNS lymphoma: A study on behalf of the EBMT and the GoCART coalition.
Ossami Saidy A, Peczynski C, Thieblemont C, Daskalakis M, Wehrli M, Beauvais D, Finke J, Schorb E, Vandenberghe P, Berning P, Stelljes M, Ayuk F, Ram R, Von Bonin M, Dreger P, Bethge W, Kuhnl A, Jost L, Stölzel F, von Tresckow B, Renner C, Fuhrmann S, Galimard JE, Michel E, Bazarbachi A, Balari AS, Schmitz N, Glass B. Ossami Saidy A, et al. Hemasphere. 2025 May 21;9(5):e70146. doi: 10.1002/hem3.70146. eCollection 2025 May. Hemasphere. 2025. PMID: 40400509 Free PMC article.
Development of a multiomics database for personalized prognostic forecasting in head and neck cancer: The Big Data to Decide EU Project.
Cavalieri S, De Cecco L, Brakenhoff RH, Serafini MS, Canevari S, Rossi S, Lanfranco D, Hoebers FJP, Wesseling FWR, Keek S, Scheckenbach K, Mattavelli D, Hoffmann T, López Pérez L, Fico G, Bologna M, Nauta I, Leemans CR, Trama A, Klausch T, Berkhof JH, Tountopoulos V, Shefi R, Mainardi L, Mercalli F, Poli T, Licitra L; BD2Decide Consortium. Cavalieri S, et al. Head Neck. 2021 Feb;43(2):601-612. doi: 10.1002/hed.26515. Epub 2020 Oct 27. Head Neck. 2021. PMID: 33107152 Free PMC article.
MS cortical lesions on DIR: not quite what they seem?
Sethi V, Muhlert N, Ron M, Golay X, Wheeler-Kingshott CA, Miller DH, Chard DT, Yousry TA. Sethi V, et al. PLoS One. 2013 Nov 11;8(11):e78879. doi: 10.1371/journal.pone.0078879. eCollection 2013. PLoS One. 2013. PMID: 24244381 Free PMC article. Clinical Trial.
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