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Variable peptide processing of a Conus (Asprella) neocostatus α-conotoxin generates bioactive toxiforms that are potent against distinct nicotinic acetylcholine receptor subtypes.
Ramones CMV, Taguchi RS, Gamba EME, Johann E Isagan AE, Watkins M, Chicote MO, Velarde MC, Villaraza AJL, Yu ET, Olivera BM, Concepcion GP, Lluisma AO. Ramones CMV, et al. Among authors: taguchi rs. Biochem Pharmacol. 2025 Mar;233:116781. doi: 10.1016/j.bcp.2025.116781. Epub 2025 Jan 27. Biochem Pharmacol. 2025. PMID: 39880316