Heterogeneity in health care pathways preceding the classical recognition of adult-onset multiple sclerosis: A multichannel state sequence analysis.
Yusuf FLA, Karim ME, Sutherland JM, Zhu F, Zhao Y, Marrie RA, Tremlett H.
Yusuf FLA, et al.
Mult Scler Relat Disord. 2025 Oct;102:106595. doi: 10.1016/j.msard.2025.106595. Epub 2025 Jun 25.
Mult Scler Relat Disord. 2025.
PMID: 40651073
Free article.
We applied hierarchical cluster analysis with Hubert's C Index to group similar pathways. RESULTS: Before the first demyelinating event, 9 pathways emerged: pathways for low (25 % of cohort), moderate (25 %) and high (18 %) healthcare use; pathways representing steadily in …
We applied hierarchical cluster analysis with Hubert's C Index to group similar pathways. RESULTS: Before the first demyelinating eve …