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2017 2
2018 3
2019 1
2020 1
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Page 1
Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals).
Schiedel M, Herp D, Hammelmann S, Swyter S, Lehotzky A, Robaa D, Oláh J, Ovádi J, Sippl W, Jung M. Schiedel M, et al. Among authors: Swyter S. J Med Chem. 2018 Jan 25;61(2):482-491. doi: 10.1021/acs.jmedchem.6b01872. Epub 2017 Apr 17. J Med Chem. 2018. PMID: 28379698
Azologization and repurposing of a hetero-stilbene-based kinase inhibitor: towards the design of photoswitchable sirtuin inhibitors.
Grathwol CW, Wössner N, Swyter S, Smith AC, Tapavicza E, Hofstetter RK, Bodtke A, Jung M, Link A. Grathwol CW, et al. Among authors: Swyter S. Beilstein J Org Chem. 2019 Sep 16;15:2170-2183. doi: 10.3762/bjoc.15.214. eCollection 2019. Beilstein J Org Chem. 2019. PMID: 31598174 Free PMC article.
Three-Component Aminoalkylations Yielding Dihydronaphthoxazine-Based Sirtuin Inhibitors: Scaffold Modification and Exploration of Space for Polar Side-Chains.
Vojacek S, Beese K, Alhalabi Z, Swyter S, Bodtke A, Schulzke C, Jung M, Sippl W, Link A. Vojacek S, et al. Among authors: Swyter S. Arch Pharm (Weinheim). 2017 Jul;350(7). doi: 10.1002/ardp.201700097. Epub 2017 May 26. Arch Pharm (Weinheim). 2017. PMID: 28547816
Sirtuin 1 Inhibiting Thiocyanates (S1th)-A New Class of Isotype Selective Inhibitors of NAD+ Dependent Lysine Deacetylases.
Wössner N, Alhalabi Z, González J, Swyter S, Gan J, Schmidtkunz K, Zhang L, Vaquero A, Ovaa H, Einsle O, Sippl W, Jung M. Wössner N, et al. Among authors: Swyter S. Front Oncol. 2020 Apr 30;10:657. doi: 10.3389/fonc.2020.00657. eCollection 2020. Front Oncol. 2020. PMID: 32426286 Free PMC article.
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