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Loss- or Gain-of-Function Mutations in ACOX1 Cause Axonal Loss via Different Mechanisms.
Chung HL, Wangler MF, Marcogliese PC, Jo J, Ravenscroft TA, Zuo Z, Duraine L, Sadeghzadeh S, Li-Kroeger D, Schmidt RE, Pestronk A, Rosenfeld JA, Burrage L, Herndon MJ, Chen S; Members of Undiagnosed Diseases Network, Shillington A, Vawter-Lee M, Hopkin R, Rodriguez-Smith J, Henrickson M, Lee B, Moser AB, Jones RO, Watkins P, Yoo T, Mar S, Choi M, Bucelli RC, Yamamoto S, Lee HK, Prada CE, Chae JH, Vogel TP, Bellen HJ. Chung HL, et al. Neuron. 2020 May 20;106(4):589-606.e6. doi: 10.1016/j.neuron.2020.02.021. Epub 2020 Mar 12. Neuron. 2020. PMID: 32169171 Free PMC article.
ACOX1 (acyl-CoA oxidase 1) encodes the first and rate-limiting enzyme of the very-long-chain fatty acid (VLCFA) beta-oxidation pathway in peroxisomes and leads to H(2)O(2) production. Unexpectedly, Drosophila (d) ACOX1 is mostly expressed and required in glia, and loss of …
ACOX1 (acyl-CoA oxidase 1) encodes the first and rate-limiting enzyme of the very-long-chain fatty acid (VLCFA) beta-oxidation pathway in pe …
Effect of cold stress on polyamine metabolism and antioxidant responses in chickpea.
Amini S, Maali-Amiri R, Kazemi-Shahandashti SS, López-Gómez M, Sadeghzadeh B, Sobhani-Najafabadi A, Kariman K. Amini S, et al. J Plant Physiol. 2021 Mar-Apr;258-259:153387. doi: 10.1016/j.jplph.2021.153387. Epub 2021 Feb 15. J Plant Physiol. 2021. PMID: 33636556
In this study, the potential role of PAs along with the antioxidative defense systems were assessed in two chickpea genotypes (Sel96th11439, cold-tolerant and ILC533, cold-sensitive) under CS conditions. Six days after exposure to CS, the leaf H(2)O(2) content and electrol …
In this study, the potential role of PAs along with the antioxidative defense systems were assessed in two chickpea genotypes (Sel96th11439, …
99mTc labeled D(LPR): A novel retro-inverso peptide for VEGF receptor-1 targeted tumor imaging.
Rezazadeh F, Sadeghzadeh N, Abedi SM, Abediankenari S. Rezazadeh F, et al. Nucl Med Biol. 2018 Jul-Aug;62-63:54-62. doi: 10.1016/j.nucmedbio.2018.05.005. Epub 2018 May 31. Nucl Med Biol. 2018. PMID: 29885559
METHODS: Two different (D)(LPR) analogs were designed and compared based on conjugation of HYNIC at peptide's C or N terminal and then labeled with technetium-99m using tricine/EDDA as an exchange coligands. ...The K(d) value for (99m)Tc-peptide 1 and (99m)Tc-peptide 2 wer …
METHODS: Two different (D)(LPR) analogs were designed and compared based on conjugation of HYNIC at peptide's C or N terminal and the …