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Page 1
Modeling coronavirus spike protein dynamics: implications for immunogenicity and immune escape.
Kunkel G, Madani M, White SJ, Verardi PH, Tarakanova A. Kunkel G, et al. Among authors: madani m. Biophys J. 2021 Dec 21;120(24):5592-5618. doi: 10.1016/j.bpj.2021.11.009. Epub 2021 Nov 10. Biophys J. 2021. PMID: 34767789 Free PMC article.
We then analyze local protein domain dynamics of the S protein systems and their thermal stability to characterize structural and dynamical variability among them. ...We then compare SARS-CoV-2 S protein dynamics to SARS-CoV and MERS-CoV S proteins to investi …
We then analyze local protein domain dynamics of the S protein systems and their thermal stability to characterize structural and dyn …
Osimertinib in NSCLC With Atypical EGFR-Activating Mutations: A Retrospective Multicenter Study.
Ji J, Aredo JV, Piper-Vallillo A, Huppert L, Rotow JK, Husain H, Stewart S, Cobb R, Wakelee HA, Blakely CM, Wong ML, Gubens MA, Madani MH, Digumarthy SR, McCoach C, Piotrowska Z, Neal JW, Riess JW. Ji J, et al. Among authors: madani mh. JTO Clin Res Rep. 2023 Jan 10;4(3):100459. doi: 10.1016/j.jtocrr.2022.100459. eCollection 2023 Mar. JTO Clin Res Rep. 2023. PMID: 36879929 Free PMC article.
METHODS: Patients with metastatic NSCLC treated with osimertinib, harboring at least one atypical EGFR mutation, excluding concurrent deletion of exon 19, L858R, or T790M mutations, from six U.S. academic cancer centers were included. Baseline clinical characteristics were …
METHODS: Patients with metastatic NSCLC treated with osimertinib, harboring at least one atypical EGFR mutation, excluding concurrent deleti …
Improved inter-residue contact prediction via a hybrid generative model and dynamic loss function.
Madani M, Mahdi Behzadi M, Song D, Ilies HT, Tarakanova A. Madani M, et al. Comput Struct Biotechnol J. 2022 Nov 12;20:6138-6148. doi: 10.1016/j.csbj.2022.11.020. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 36420166 Free PMC article.
Protein contact maps represent spatial pairwise inter-residue interactions, providing a protein's translationally and rotationally invariant topological representation. Accurate contact map prediction has been a critical driving force for improving protein structure determ …
Protein contact maps represent spatial pairwise inter-residue interactions, providing a protein's translationally and rotationally in …
Oncologic Outcomes and Predictors in Patients with Stage PT3aNxM0 Renal Cell Carcinoma Following Radical Nephrectomy.
Soltani MH, Dadpour M, Goodarzi M, Khabazian R, Narouie B, Borumandnia N, Madani MH. Soltani MH, et al. Among authors: madani mh. Urol Res Pract. 2023 Jan;49(1):25-32. doi: 10.5152/tud.2023.22072. Urol Res Pract. 2023. PMID: 37877835 Free PMC article.

After performing multivariate analysis, higher nuclear Fuhrman's grade (P < .001) and simultaneous involvement of the renal vein and perinephric fat (P < .001) were found to be predictive of cancerrelated mortality. Advanced nuclear Fuhrman's grade was the onl

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After performing multivariate analysis, higher nuclear Fuhrman's grade (P < .001) and simultaneous involvement of the renal vein a

…
Evaluation of responses to cardiac imaging questions by the artificial intelligence large language model ChatGPT.
Monroe CL, Abdelhafez YG, Atsina K, Aman E, Nardo L, Madani MH. Monroe CL, et al. Among authors: madani mh. Clin Imaging. 2024 Aug;112:110193. doi: 10.1016/j.clinimag.2024.110193. Epub 2024 May 23. Clin Imaging. 2024. PMID: 38820977 Free article.
PURPOSE: To assess ChatGPT's ability as a resource for educating patients on various aspects of cardiac imaging, including diagnosis, imaging modalities, indications, interpretation of radiology reports, and management. ...
PURPOSE: To assess ChatGPT's ability as a resource for educating patients on various aspects of cardiac imaging, including diagnosis, …
Modeling nearshore-offshore water exchange in Lake Ontario.
Hlevca B, Howell ET, Valipour R, Madani M. Hlevca B, et al. Among authors: madani m. PLoS One. 2025 Jan 8;20(1):e0298702. doi: 10.1371/journal.pone.0298702. eCollection 2025. PLoS One. 2025. PMID: 39775252 Free PMC article.
The water quality and resources of Lake Ontario's nearshore ecosystem undergo heightened stress, particularly along the northwest shoreline. ...The dispersal pattern, as revealed by a passive tracer released from eight points around the model lake's perimeter, indic …
The water quality and resources of Lake Ontario's nearshore ecosystem undergo heightened stress, particularly along the northwest sho …
DSResSol: A Sequence-Based Solubility Predictor Created with Dilated Squeeze Excitation Residual Networks.
Madani M, Lin K, Tarakanova A. Madani M, et al. Int J Mol Sci. 2021 Dec 17;22(24):13555. doi: 10.3390/ijms222413555. Int J Mol Sci. 2021. PMID: 34948354 Free PMC article.
Protein solubility is an important thermodynamic parameter that is critical for the characterization of a protein's function, and a key determinant for the production yield of a protein in both the research setting and within industrial (e.g., pharmaceutical) applications. …
Protein solubility is an important thermodynamic parameter that is critical for the characterization of a protein's function, and a k …
Iatrogenic chest tube placement within the heart following a large pneumothorax.
Zoghi S, Brock CL, Atsina K, Abdelhafez YG, Sen F, Nardo L, Madani MH. Zoghi S, et al. Among authors: madani mh. Radiol Case Rep. 2025 May 20;20(8):3875-3878. doi: 10.1016/j.radcr.2025.04.089. eCollection 2025 Aug. Radiol Case Rep. 2025. PMID: 40492159 Free PMC article.
Pulsatile bleeding was observed during chest tube placement, and the tube's tip was later found on CT of the thorax to be located within the heart. Although the patient recovered by postoperative day 13 and was subsequently discharged, this case highlights the importance o …
Pulsatile bleeding was observed during chest tube placement, and the tube's tip was later found on CT of the thorax to be located wit …
17 results