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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1957 1
1965 1
1973 2
1974 1
1976 2
1977 1
1978 5
1979 1
1980 1
1984 1
1985 1
1986 1
1988 2
1990 1
1991 2
1992 1
1993 1
1994 4
1995 2
1996 6
1997 4
1998 4
1999 4
2000 4
2001 4
2002 2
2003 3
2004 3
2005 7
2006 4
2007 3
2008 1
2009 3
2010 2
2011 7
2012 3
2013 5
2014 8
2015 10
2016 17
2017 17
2018 11
2019 9
2020 20
2021 20
2022 19
2023 23

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224 results

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Page 1
Early Active Mobilization during Mechanical Ventilation in the ICU.
TEAM Study Investigators and the ANZICS Clinical Trials Group; Hodgson CL, Bailey M, Bellomo R, Brickell K, Broadley T, Buhr H, Gabbe BJ, Gould DW, Harrold M, Higgins AM, Hurford S, Iwashyna TJ, Serpa Neto A, Nichol AD, Presneill JJ, Schaller SJ, Sivasuthan J, Tipping CJ, Webb S, Young PJ. TEAM Study Investigators and the ANZICS Clinical Trials Group, et al. N Engl J Med. 2022 Nov 10;387(19):1747-1758. doi: 10.1056/NEJMoa2209083. Epub 2022 Oct 26. N Engl J Med. 2022. PMID: 36286256 Clinical Trial.
Clinical experience of switching patients with severe hemophilia to rVIII-SingleChain or rIX-FP.
Oldenburg J, Pipe SW, Mancuso ME, Klamroth R, Hassoun A, Olivieri M, Goldmann G, Kenet G, Miesbach W, Schmiedl J, Hegemann I. Oldenburg J, et al. Curr Med Res Opin. 2023 Feb;39(2):219-225. doi: 10.1080/03007995.2022.2116173. Epub 2022 Sep 28. Curr Med Res Opin. 2023. PMID: 36170120 Review.
Both aspects can have long-term effects on joint health. Products, such as rVIII-SingleChain and rIX-FP have been developed to reduce the treatment burden for patients with hemophilia and optimize prophylactic efficacy. ...RESULTS: It is important to take into consideratio …
Both aspects can have long-term effects on joint health. Products, such as rVIII-SingleChain and rIX-FP have been developed to reduce …
Glucagon Physiology.
Rix I, Nexøe-Larsen C, Bergmann NC, Lund A, Knop FK. Rix I, et al. 2019 Jul 16. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. 2019 Jul 16. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. PMID: 25905350 Free Books & Documents. Review.
Real-World Utilisation and Bleed Rates in Patients with Haemophilia B Who Switched to Recombinant Factor IX Fusion Protein (rIX-FP): A Retrospective International Analysis.
Hermans C, Marino R, Lambert C, Mangles S, Sommerer P, Rives V, Maro G, Malcangi G. Hermans C, et al. Adv Ther. 2020 Jun;37(6):2988-2998. doi: 10.1007/s12325-020-01300-6. Epub 2020 Apr 24. Adv Ther. 2020. PMID: 32333327 Free PMC article.
This analysis evaluated real-world outcomes in patients switching to rIX-FP from the previous FIX product in Italy, Belgium and the UK. ...Patients were included in the analysis if they had been treated with rIX-FP for 8 weeks. Data were compared between rIX- …
This analysis evaluated real-world outcomes in patients switching to rIX-FP from the previous FIX product in Italy, Belgium and the U …
Long-term safety and efficacy of rIX-FP prophylaxis with extended dosing intervals up to 21 days in adults/adolescents with hemophilia B.
Mancuso ME, Lubetsky A, Pan-Petesch B, Lissitchkov T, Nagao A, Seifert W, Li Y, Santagostino E. Mancuso ME, et al. J Thromb Haemost. 2020 May;18(5):1065-1074. doi: 10.1111/jth.14778. Epub 2020 Mar 30. J Thromb Haemost. 2020. PMID: 32078256 Free PMC article.
BACKGROUND: An international, multicenter extension study evaluated recombinant fusion protein linking recombinant coagulation factor IX (FIX) with recombinant human albumin (rIX-FP) in hemophilia B (FIX 2%) patients previously enrolled in a phase III study or who initiate …
BACKGROUND: An international, multicenter extension study evaluated recombinant fusion protein linking recombinant coagulation factor IX (FI …
Improved kinetics of rIX-FP, a recombinant fusion protein linking factor IX with albumin, in cynomolgus monkeys and hemophilia B dogs.
Nolte MW, Nichols TC, Mueller-Cohrs J, Merricks EP, Pragst I, Zollner S, Dickneite G. Nolte MW, et al. J Thromb Haemost. 2012 Aug;10(8):1591-9. doi: 10.1111/j.1538-7836.2012.04826.x. J Thromb Haemost. 2012. PMID: 22726310 Free PMC article.
OBJECTIVES: The aim of our studies was to investigate the pharmacokinetic (PK) and pharmacodynamic (PD) profile of a recombinant fusion protein linking coagulation FIX with albumin (rIX-FP). METHODS: Cynomolgus monkeys and hemophilia B dogs received single intravenous dose …
OBJECTIVES: The aim of our studies was to investigate the pharmacokinetic (PK) and pharmacodynamic (PD) profile of a recombinant fusion prot …
Infrastructure and Injury Prevention in Cycling.
Rix K, Sakamoto I. Rix K, et al. Phys Med Rehabil Clin N Am. 2022 Feb;33(1):123-134. doi: 10.1016/j.pmr.2021.08.009. Epub 2021 Oct 20. Phys Med Rehabil Clin N Am. 2022. PMID: 34798994 Review.
Health-related quality of life in paediatric haemophilia B patients treated with rIX-FP.
von Mackensen S, Shah J, Seifert W, Kenet G. von Mackensen S, et al. Haemophilia. 2019 Jan;25(1):45-53. doi: 10.1111/hae.13624. Epub 2018 Nov 14. Haemophilia. 2019. PMID: 30427091 Free PMC article. Clinical Trial.
AIMS: To measure the effect of rIX-FP prophylaxis on the HRQoL of paediatric patients and treatment satisfaction in their caregivers using the Haemo-QoL and Hemo-SAT(P) questionnaires, respectively. ...CONCLUSION: Prophylaxis with rIX-FP led to substantial improveme …
AIMS: To measure the effect of rIX-FP prophylaxis on the HRQoL of paediatric patients and treatment satisfaction in their caregivers …
IDELVION: A Comprehensive Review of Clinical Trial and Real-World Data.
Escobar M, Mancuso ME, Hermans C, Leissinger C, Seifert W, Li Y, McKeand W, Oldenburg J. Escobar M, et al. J Clin Med. 2022 Feb 18;11(4):1071. doi: 10.3390/jcm11041071. J Clin Med. 2022. PMID: 35207344 Free PMC article. Review.
This review outlines data from all previously treated patients in the Prophylaxis and On-Demand Treatment using Longer Half-Life rIX-FP (PROLONG-9FP) clinical trial program and summarizes real-world data evaluating the use of rIX-FP in routine clinical practice. In …
This review outlines data from all previously treated patients in the Prophylaxis and On-Demand Treatment using Longer Half-Life rIX- …
224 results