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Effect of Leishmania RNA virus 2 on virulence factors and cytokines gene expression in a human macrophage infected with Leishmania major: A preliminary study.
Rahmanipour M, Mohebali M, Koosha M, Kazemirad E, Yasami-Khiabani S, Mirjalali H, Hajjaran H. Rahmanipour M, et al. Among authors: yasami khiabani s. Exp Parasitol. 2023 Mar;246:108459. doi: 10.1016/j.exppara.2022.108459. Epub 2022 Dec 31. Exp Parasitol. 2023. PMID: 36596336
Findings showed that the presence of LRV2 in L. major was able to increase the expression of gp63, hsp70, and cpb genes; also, we observed lower levels of expression in cytokine genes of IL-1beta, IL-8, IL-12 in the presence of LRV2(+), which are critical factors in the host's …
Findings showed that the presence of LRV2 in L. major was able to increase the expression of gp63, hsp70, and cpb genes; also, we observed l …