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MCPH1 inhibits Condensin II during interphase by regulating its SMC2-Kleisin interface.
Houlard M, Cutts EE, Shamim MS, Godwin J, Weisz D, Presser Aiden A, Lieberman Aiden E, Schermelleh L, Vannini A, Nasmyth K. Houlard M, et al. Elife. 2021 Dec 1;10:e73348. doi: 10.7554/eLife.73348. Elife. 2021. PMID: 34850681 Free PMC article.
While condensin normally configures chromosomes exclusively during mitosis, cohesin does so during interphase. The processivity of cohesin's loop extrusion during interphase is limited by a regulatory factor called WAPL, which induces cohesin to dissociate from chromosomes …
While condensin normally configures chromosomes exclusively during mitosis, cohesin does so during interphase. The processivity of cohesin' …
Where are the most ancient stars in the Milky Way?
El-Badry K, Bland-Hawthorn J, Wetzel A, Quataert E, Weisz DR, Boylan-Kolchin M, Hopkins PF, Faucher-Giguère CA, Kereš D, Garrison-Kimmel S. El-Badry K, et al. Mon Not R Astron Soc. 2018 Oct;480(1):652-668. doi: 10.1093/mnras/sty1864. Epub 2018 Jul 14. Mon Not R Astron Soc. 2018. PMID: 30581239 Free PMC article.
The oldest stars in the Milky Way (MW) bear imprints of the Galaxy's early assembly history. We use FIRE cosmological zoom-in simulations of three MW-mass disc galaxies to study the spatial distribution, chemistry, and kinematics of the oldest surviving stars (z (fo …
The oldest stars in the Milky Way (MW) bear imprints of the Galaxy's early assembly history. We use FIRE cosmological zoom-in simulat …
Chromosome-length genome assembly and linkage map of a critically endangered Australian bird: the helmeted honeyeater.
Robledo-Ruiz DA, Gan HM, Kaur P, Dudchenko O, Weisz D, Khan R, Lieberman Aiden E, Osipova E, Hiller M, Morales HE, Magrath MJL, Clarke RH, Sunnucks P, Pavlova A. Robledo-Ruiz DA, et al. Gigascience. 2022 Mar 29;11:giac025. doi: 10.1093/gigascience/giac025. Gigascience. 2022. PMID: 35348671 Free PMC article.
Using a pedigree of 257 birds and 53,111 single-nucleotide polymorphisms, we obtained high-density linkage and recombination maps for 25 autosomes and Z chromosome. The total sex-averaged linkage map was 1,347 cM long, with the male map being 6.7% longer than the female ma …
Using a pedigree of 257 birds and 53,111 single-nucleotide polymorphisms, we obtained high-density linkage and recombination maps for 25 aut …
Physiology of Low Blood Pressure During the First Day After Birth Among Extremely Preterm Neonates.
Aldana-Aguirre JC, Deshpande P, Jain A, Weisz DE. Aldana-Aguirre JC, et al. J Pediatr. 2021 Sep;236:40-46.e3. doi: 10.1016/j.jpeds.2021.05.026. Epub 2021 May 18. J Pediatr. 2021. PMID: 34019882

RESULTS: Neonates with hypotension had a higher frequency of patent ductus arteriosus 1.5 mm (71% vs 15%; P < .001) and ductal size (median diameter, 1.6 mm [IQR, 1.4-2.1] vs 1.0 mm [IQR, 0-1.3]; P = .002), higher echocardiography indices of left ventricular systolic function

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RESULTS: Neonates with hypotension had a higher frequency of patent ductus arteriosus 1.5 mm (71% vs 15%; P < .001) and ductal size (medi

…
16 results