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Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.
Szczepańska K, Karcz T, Dichiara M, Mogilski S, Kalinowska-Tłuścik J, Pilarski B, Leniak A, Pietruś W, Podlewska S, Popiołek-Barczyk K, Humphrys LJ, Ruiz-Cantero MC, Reiner-Link D, Leitzbach L, Łażewska D, Pockes S, Górka M, Zmysłowski A, Calmels T, Cobos EJ, Marrazzo A, Stark H, Bojarski AJ, Amata E, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: podlewska s. J Med Chem. 2023 Jul 27;66(14):9658-9683. doi: 10.1021/acs.jmedchem.3c00430. Epub 2023 Jul 7. J Med Chem. 2023. PMID: 37418295 Free PMC article.
The first-in-class 1,3,5-triazine-derived dual 5-HT6R/FAAH modulators in search for potential drug against neurodegenerative diseases with cognitive impairment.
Czarnota-Łydka K, Kucwaj-Brysz K, Mordyl B, Głuch-Lutwin M, Karcz T, Jastrzębska-Więsek M, Partyka A, Dąbrowska M, Satała G, Sudoł-Tałaj S, Brunetti L, de Candia M, Purgatorio R, Cerini M, Piemontese L, Podlewska S, Latacz G, Starek M, Wesołowska A, Carrieri A, Handzlik J. Czarnota-Łydka K, et al. Among authors: podlewska s. Eur J Med Chem. 2025 Nov 15;298:118026. doi: 10.1016/j.ejmech.2025.118026. Epub 2025 Aug 5. Eur J Med Chem. 2025. PMID: 40774068 Free article.
Structural insights into serotonin receptor ligands polypharmacology.
Podlewska S, Kafel R, Lacivita E, Satała G, Kooistra AJ, Vass M, de Graaf C, Leopoldo M, Bojarski AJ, Mordalski S. Podlewska S, et al. Eur J Med Chem. 2018 May 10;151:797-814. doi: 10.1016/j.ejmech.2018.04.010. Epub 2018 Apr 6. Eur J Med Chem. 2018. PMID: 29679900
52 results