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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1941 1
1943 1
1945 2
1946 1
1947 1
1948 1
1949 1
1950 2
1951 2
1953 2
1954 2
1955 6
1956 1
1959 2
1961 5
1962 4
1963 28
1964 61
1965 69
1966 125
1967 124
1968 92
1969 48
1970 43
1971 13
1972 12
1973 13
1974 22
1975 18
1976 34
1977 34
1978 39
1979 42
1980 47
1981 43
1982 43
1983 48
1984 46
1985 55
1986 55
1987 107
1988 120
1989 178
1990 177
1991 147
1992 206
1993 193
1994 213
1995 247
1996 218
1997 259
1998 308
1999 291
2000 394
2001 517
2002 624
2003 613
2004 759
2005 944
2006 1016
2007 985
2008 1150
2009 1164
2010 1254
2011 1383
2012 1388
2013 1551
2014 1814
2015 1981
2016 2204
2017 2309
2018 2390
2019 2496
2020 1520
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29,362 results
Results by year
Filters applied: . Clear all The following term was not found in PubMed: Cuvillez
Page 1
The structure of the SAM/SAH-binding riboswitch.
Weickhmann AK, Keller H, Wurm JP, Strebitzer E, Juen MA, Kremser J, Weinberg Z, Kreutz C, Duchardt-Ferner E, Wöhnert J. Weickhmann AK, et al. Nucleic Acids Res. 2019 Mar 18;47(5):2654-2665. doi: 10.1093/nar/gky1283. Nucleic Acids Res. 2019. PMID: 30590743 Free PMC article.
S-adenosylmethionine (SAM) is a central metabolite since it is used as a methyl group donor in many different biochemical reactions. Many bacteria control intracellular SAM concentrations using riboswitch-based mechanisms. A number of structurally different riboswit …
S-adenosylmethionine (SAM) is a central metabolite since it is used as a methyl group donor in many different biochemical reactions. …
The Sam Domain of EphA2 Receptor and its Relevance to Cancer: A Novel Challenge for Drug Discovery?
Mercurio FA, Leone M. Mercurio FA, et al. Curr Med Chem. 2016;23(42):4718-4734. doi: 10.2174/0929867323666161101100722. Curr Med Chem. 2016. PMID: 27804871 Review.
EphA2-Sam binds the Sam domain from the lipid phosphatase Ship2 and the first Sam domain of Odin. Sam-Sam interactions may be important to regulate ligand-induced receptor endocytosis and degradation i.e., processes that could be engaged against …
EphA2-Sam binds the Sam domain from the lipid phosphatase Ship2 and the first Sam domain of Odin. Sam-Sam
Segmental arterial mediolysis (SAM): Systematic review and analysis of 143 cases.
Skeik N, Olson SL, Hari G, Pavia ML. Skeik N, et al. Vasc Med. 2019 Dec;24(6):549-563. doi: 10.1177/1358863X19873410. Vasc Med. 2019. PMID: 31793853
Current literature lacks consensus on diagnostic criteria and management options for SAM. This review summarizes 143 cases and aims to advance appropriate recognition and management of SAM. Literature review of all relevant SAM case studies from 2005 to 2018 …
Current literature lacks consensus on diagnostic criteria and management options for SAM. This review summarizes 143 cases and aims t …
Structural insights into SAM domain-mediated tankyrase oligomerization.
DaRosa PA, Ovchinnikov S, Xu W, Klevit RE. DaRosa PA, et al. Protein Sci. 2016 Sep;25(9):1744-52. doi: 10.1002/pro.2968. Epub 2016 Jul 4. Protein Sci. 2016. PMID: 27328430 Free PMC article.
Tankyrase proteins include a sterile alpha motif (SAM) domain that undergoes oligomerization in vitro and in vivo. However, the SAM domains of TNKS1 and TNKS2 have not been structurally characterized and the mode of oligomerization is not yet defined. ...Furthermore …
Tankyrase proteins include a sterile alpha motif (SAM) domain that undergoes oligomerization in vitro and in vivo. However, the SA
SAM-VI RNAs selectively bind S-adenosylmethionine and exhibit similarities to SAM-III riboswitches.
Mirihana Arachchilage G, Sherlock ME, Weinberg Z, Breaker RR. Mirihana Arachchilage G, et al. RNA Biol. 2018 Mar 4;15(3):371-378. doi: 10.1080/15476286.2017.1399232. Epub 2018 Feb 12. RNA Biol. 2018. PMID: 29106323 Free PMC article.
Here, we report a potential sixth member of this pervasive riboswitch family, called SAM-VI, which is predominantly found in Bifidobacterium species. SAM-VI aptamers selectively bind the cofactor SAM and strongly discriminate against SAH. The consensus sequen …
Here, we report a potential sixth member of this pervasive riboswitch family, called SAM-VI, which is predominantly found in Bifidoba …
Have You Seen SAM?
Fleming S, Tang R, Ferguson J, Kwok R, Jansen S. Fleming S, et al. EJVES Short Rep. 2018 Feb 6;38:8-11. doi: 10.1016/j.ejvssr.2017.12.001. eCollection 2018. EJVES Short Rep. 2018. PMID: 29780893 Free PMC article.
REPORT: A case is reported of a patient with SAM affecting the renal arteries bilaterally, where the diagnosis was made by excluding other inflammatory, immunological, and infectious mimickers. DISCUSSION: As SAM carries a significant mortality and morbidity from en …
REPORT: A case is reported of a patient with SAM affecting the renal arteries bilaterally, where the diagnosis was made by excluding …
Expanding Radical SAM Chemistry by Using Radical Addition Reactions and SAM Analogues.
Ji X, Li Y, Xie L, Lu H, Ding W, Zhang Q. Ji X, et al. Angew Chem Int Ed Engl. 2016 Sep 19;55(39):11845-8. doi: 10.1002/anie.201605917. Epub 2016 Aug 30. Angew Chem Int Ed Engl. 2016. PMID: 27573794
Radical S-adenosyl-l-methionine (SAM) enzymes utilize a [4Fe-4S] cluster to bind SAM and reductively cleave its carbon-sulfur bond to produce a highly reactive 5'-deoxyadenosyl (dAdo) radical. ...Our study demonstrates a promising strategy in expanding radical SA
Radical S-adenosyl-l-methionine (SAM) enzymes utilize a [4Fe-4S] cluster to bind SAM and reductively cleave its carbon-sulfur …
Co-administration of GM-CSF expressing RNA is a powerful tool to enhance potency of SAM-based vaccines.
Manara C, Brazzoli M, Piccioli D, Taccone M, D'Oro U, Maione D, Frigimelica E. Manara C, et al. Vaccine. 2019 Jul 9;37(30):4204-4213. doi: 10.1016/j.vaccine.2019.04.028. Epub 2019 Jun 18. Vaccine. 2019. PMID: 31227353
To enhance SAM immunogenicity, we selected murine granulocyte-macrophage colony-stimulating factor (GM-CSF) as a model chemoattractant for APCs, and developed a SAM-GM-CSF vector. ...Furthermore, co-immunization with SAM-GM-CSF and SAM-NP provided an i …
To enhance SAM immunogenicity, we selected murine granulocyte-macrophage colony-stimulating factor (GM-CSF) as a model chemoattractan …
S-adenosyl methionine (SAM) attenuates the development of tolerance to analgesic activity of morphine in rats.
Katyal J, Kumar H, Joshi D, Gupta YK. Katyal J, et al. Neurosci Lett. 2017 Apr 3;645:67-73. doi: 10.1016/j.neulet.2017.02.054. Epub 2017 Feb 22. Neurosci Lett. 2017. PMID: 28237804
To evaluate the effect of SAM on morphine tolerance, SAM 800mg/kg was administered orally (p.o.), 45min prior to each dose of morphine. The analgesic activity of SAM and opioidergic component in its activity was also evaluated. RESULTS: Co-administration of m …
To evaluate the effect of SAM on morphine tolerance, SAM 800mg/kg was administered orally (p.o.), 45min prior to each dose of …
S-adenosylmethionine (SAM)-accumulating sake yeast suppresses acute alcohol-induced liver injury in mice.
Izu H, Shobayashi M, Manabe Y, Goto K, Iefuji H. Izu H, et al. Biosci Biotechnol Biochem. 2006 Dec;70(12):2982-9. doi: 10.1271/bbb.60377. Epub 2006 Dec 7. Biosci Biotechnol Biochem. 2006. PMID: 17151469 Free article.
To enhance the suppression of acute alcoholic liver injury by sake yeast, we prepared SAM-accumulating sake yeast (SAM yeast). ...In addition, the SAM yeast-fed mice did not show an ethanol-induced decrease in hepatic SAM level, suggesting that a disor …
To enhance the suppression of acute alcoholic liver injury by sake yeast, we prepared SAM-accumulating sake yeast (SAM yeast). …
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