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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1921 1
1941 1
1943 1
1945 2
1946 1
1947 1
1948 1
1949 1
1950 2
1951 2
1953 2
1954 2
1955 6
1956 1
1959 2
1961 5
1962 4
1963 28
1964 61
1965 69
1966 125
1967 124
1968 92
1969 48
1970 43
1971 13
1972 12
1973 13
1974 22
1975 18
1976 34
1977 34
1978 39
1979 42
1980 47
1981 43
1982 43
1983 48
1984 47
1985 55
1986 55
1987 107
1988 120
1989 178
1990 177
1991 147
1992 206
1993 194
1994 213
1995 247
1996 218
1997 259
1998 308
1999 291
2000 394
2001 517
2002 625
2003 616
2004 762
2005 944
2006 1020
2007 988
2008 1154
2009 1168
2010 1262
2011 1382
2012 1395
2013 1553
2014 1824
2015 1994
2016 2224
2017 2328
2018 2435
2019 2541
2020 2809
2021 3210
2022 1897
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35,064 results
Results by year
Filters applied: . Clear all The following term was not found in PubMed: Wallen-Russell
Page 1
The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention.
Pendleton KE, Chen B, Liu K, Hunter OV, Xie Y, Tu BP, Conrad NK. Pendleton KE, et al. Cell. 2017 May 18;169(5):824-835.e14. doi: 10.1016/j.cell.2017.05.003. Cell. 2017. PMID: 28525753 Free PMC article.
Maintenance of proper levels of the methyl donor S-adenosylmethionine (SAM) is critical for a wide variety of biological processes. We demonstrate that the N(6)-adenosine methyltransferase METTL16 regulates expression of human MAT2A, which encodes the SAM synthetase …
Maintenance of proper levels of the methyl donor S-adenosylmethionine (SAM) is critical for a wide variety of biological processes. W …
Modern management of systolic anterior motion of the mitral valve.
Ibrahim M, Rao C, Ashrafian H, Chaudhry U, Darzi A, Athanasiou T. Ibrahim M, et al. Eur J Cardiothorac Surg. 2012 Jun;41(6):1260-70. doi: 10.1093/ejcts/ezr232. Epub 2012 Jan 18. Eur J Cardiothorac Surg. 2012. PMID: 22290892 Review.
Systolic anterior motion (SAM) of the mitral valve (MV) can be a life-threatening condition. ...The mechanisms of SAM are complex and depend on the functional status of the ventricle. ...
Systolic anterior motion (SAM) of the mitral valve (MV) can be a life-threatening condition. ...The mechanisms of SAM are comp …
Diversity of the reaction mechanisms of SAM-dependent enzymes.
Sun Q, Huang M, Wei Y. Sun Q, et al. Acta Pharm Sin B. 2021 Mar;11(3):632-650. doi: 10.1016/j.apsb.2020.08.011. Epub 2020 Aug 26. Acta Pharm Sin B. 2021. PMID: 33777672 Free PMC article. Review.
Methyltransferases (MTases), a major group of SAM-dependent enzymes, catalyze methyl transfer from SAM to C, O, N, and S atoms in small-molecule secondary metabolites and macromolecules, including proteins and nucleic acids. ...Herein, we mainly describe the nonmeth …
Methyltransferases (MTases), a major group of SAM-dependent enzymes, catalyze methyl transfer from SAM to C, O, N, and S atoms …
Sam Domains in Multiple Diseases.
Vincenzi M, Mercurio FA, Leone M. Vincenzi M, et al. Curr Med Chem. 2020;27(3):450-476. doi: 10.2174/0929867325666181009114445. Curr Med Chem. 2020. PMID: 30306850 Review.
This study intends to collect state-of-the-art knowledge on the different modes by which Sam domains can favor disease onset and progression. METHODS: This review was build up by searching throughout the literature, for: a) the structural properties of Sam domains, …
This study intends to collect state-of-the-art knowledge on the different modes by which Sam domains can favor disease onset and prog …
S-Adenosylmethionine.
Lu SC. Lu SC. Int J Biochem Cell Biol. 2000 Apr;32(4):391-5. doi: 10.1016/s1357-2725(99)00139-9. Int J Biochem Cell Biol. 2000. PMID: 10762064 Review.
S-Adenosyl-Lmethionine (SAM) is an important molecule in normal cell function and survival. SAM is utilized by three key metabolic pathways: transmethylation; transsulfuration; and polyamine synthesis. ...
S-Adenosyl-Lmethionine (SAM) is an important molecule in normal cell function and survival. SAM is utilized by three key metab …
The structure of the SAM/SAH-binding riboswitch.
Weickhmann AK, Keller H, Wurm JP, Strebitzer E, Juen MA, Kremser J, Weinberg Z, Kreutz C, Duchardt-Ferner E, Wöhnert J. Weickhmann AK, et al. Nucleic Acids Res. 2019 Mar 18;47(5):2654-2665. doi: 10.1093/nar/gky1283. Nucleic Acids Res. 2019. PMID: 30590743 Free PMC article.
S-adenosylmethionine (SAM) is a central metabolite since it is used as a methyl group donor in many different biochemical reactions. Many bacteria control intracellular SAM concentrations using riboswitch-based mechanisms. A number of structurally different riboswit …
S-adenosylmethionine (SAM) is a central metabolite since it is used as a methyl group donor in many different biochemical reactions. …
Radical SAM-mediated methylation reactions.
Fujimori DG. Fujimori DG. Curr Opin Chem Biol. 2013 Aug;17(4):597-604. doi: 10.1016/j.cbpa.2013.05.032. Epub 2013 Jul 5. Curr Opin Chem Biol. 2013. PMID: 23835516 Free PMC article. Review.
Recently, activities of several radical SAM methylating enzymes have been reconstituted in vitro and their mechanisms of catalysis investigated. ...Methylcobalamin serves as an intermediate methyl donor in TsrM, and is proposed to transfer the methyl group as a methyl radi …
Recently, activities of several radical SAM methylating enzymes have been reconstituted in vitro and their mechanisms of catalysis in …
Progress in the research of S-adenosyl-L-methionine production.
Chu J, Qian J, Zhuang Y, Zhang S, Li Y. Chu J, et al. Appl Microbiol Biotechnol. 2013 Jan;97(1):41-9. doi: 10.1007/s00253-012-4536-8. Epub 2012 Nov 8. Appl Microbiol Biotechnol. 2013. PMID: 23135229 Review.
This minireview mainly aims at the study of S-adenosyl-L-methionine (SAM) production by microbial fermentation. A brief introduction of the biological role and application of SAM was presented. ...The SAM-producing strains used extensively are Pichia pastoris …
This minireview mainly aims at the study of S-adenosyl-L-methionine (SAM) production by microbial fermentation. A brief introduction …
Mechanism of Radical Initiation in the Radical S-Adenosyl-l-methionine Superfamily.
Broderick WE, Hoffman BM, Broderick JB. Broderick WE, et al. Acc Chem Res. 2018 Nov 20;51(11):2611-2619. doi: 10.1021/acs.accounts.8b00356. Epub 2018 Oct 15. Acc Chem Res. 2018. PMID: 30346729 Free PMC article. Review.
A reduced [4Fe-4S](+) cluster provides the electron needed for the reductive cleavage of SAM. The resulting [4Fe-4S](2+) cluster can be rereduced either by an external reductant, with SAM acting as a cosubstrate, or by an electron provided during the reformation of …
A reduced [4Fe-4S](+) cluster provides the electron needed for the reductive cleavage of SAM. The resulting [4Fe-4S](2+) cluster can …
Smoking-attributable mortality in Spain: A systematic review.
Rey-Brandariz J, Pérez-Ríos M, Santiago-Pérez MI, Varela-Lema L, Giraldo-Osorio A, Mourino N, Ruano-Ravina A. Rey-Brandariz J, et al. Adicciones. 2021 Jun 15;0(0):1619. doi: 10.20882/adicciones.1619. Online ahead of print. Adicciones. 2021. PMID: 34171115 Free article. English, Spanish.
Smoking-attributable mortality (SAM) is an indicator that reflects the evolution of the tobacco epidemic at the population level. ...The first estimate of SAM in Spain dates from 1978 and the last from 2017. Twelve of the studies found estimated SAM at nation …
Smoking-attributable mortality (SAM) is an indicator that reflects the evolution of the tobacco epidemic at the population level. ... …
35,064 results
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