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Phenotypic screening-the fast track to novel antibody discovery.

Minter RR, Sandercock AM, Rust SJ. Minter RR, et al. Among authors: sandercock am. Drug Discov Today Technol. 2017 Mar;23:83-90. doi: 10.1016/j.ddtec.2017.03.004. Epub 2017 Apr 25. Drug Discov Today Technol. 2017. PMID: 28647091 Review.

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A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.

MacGregor P, Gonzalez-Munoz AL, Jobe F, Taylor MC, Rust S, Sandercock AM, Macleod OJS, Van Bocxlaer K, Francisco AF, D'Hooge F, Tiberghien A, Barry CS, Howard P, Higgins MK, Vaughan TJ, Minter R, Carrington M. MacGregor P, et al. Among authors: sandercock am. PLoS Negl Trop Dis. 2019 May 23;13(5):e0007373. doi: 10.1371/journal.pntd.0007373. eCollection 2019 May. PLoS Negl Trop Dis. 2019. PMID: 31120889 Free PMC article.

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Phenotypic screening reveals TNFR2 as a promising target for cancer immunotherapy.

Williams GS, Mistry B, Guillard S, Ulrichsen JC, Sandercock AM, Wang J, González-Muñoz A, Parmentier J, Black C, Soden J, Freeth J, Jovanović J, Leyland R, Al-Lamki RS, Leishman AJ, Rust SJ, Stewart R, Jermutus L, Bradley JR, Bedian V, Valge-Archer V, Minter R, Wilkinson RW. Williams GS, et al. Among authors: sandercock am. Oncotarget. 2016 Oct 18;7(42):68278-68291. doi: 10.18632/oncotarget.11943. Oncotarget. 2016. PMID: 27626702 Free PMC article.

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Recombinant expression and in vitro characterisation of active Huwentoxin-IV.

Sermadiras I, Revell J, Linley JE, Sandercock A, Ravn P. Sermadiras I, et al. Among authors: sandercock a. PLoS One. 2013 Dec 6;8(12):e83202. doi: 10.1371/journal.pone.0083202. eCollection 2013. PLoS One. 2013. PMID: 24324842 Free PMC article.

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Engineering neprilysin activity and specificity to create a novel therapeutic for Alzheimer's disease.

Webster CI, Burrell M, Olsson LL, Fowler SB, Digby S, Sandercock A, Snijder A, Tebbe J, Haupts U, Grudzinska J, Jermutus L, Andersson C. Webster CI, et al. Among authors: sandercock a. PLoS One. 2014 Aug 4;9(8):e104001. doi: 10.1371/journal.pone.0104001. eCollection 2014. PLoS One. 2014. PMID: 25089527 Free PMC article.

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AU-rich RNA-binding induces changes in the quaternary structure of AUH.

Kurimoto K, Kuwasako K, Sandercock AM, Unzai S, Robinson CV, Muto Y, Yokoyama S. Kurimoto K, et al. Among authors: sandercock am. Proteins. 2009 May 1;75(2):360-72. doi: 10.1002/prot.22246. Proteins. 2009. PMID: 18831052

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Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling.

Sandercock AM, Rust S, Guillard S, Sachsenmeier KF, Holoweckyj N, Hay C, Flynn M, Huang Q, Yan K, Herpers B, Price LS, Soden J, Freeth J, Jermutus L, Hollingsworth R, Minter R. Sandercock AM, et al. Mol Cancer. 2015 Jul 31;14:147. doi: 10.1186/s12943-015-0415-0. Mol Cancer. 2015. PMID: 26227951 Free PMC article.

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Identification of the cis‑molecular neighbours of the immune checkpoint protein B7‑H4 in the breast cancer cell‑line SK‑BR‑3 by proteomic proximity labelling.

Rees JS, Cheung LCC, Hamaia SW, Davies G, Sandercock A, Lilley KS, Tigue N, Jackson AP. Rees JS, et al. Among authors: sandercock a. Int J Oncol. 2020 Jul;57(1):87-99. doi: 10.3892/ijo.2020.5037. Epub 2020 Apr 3. Int J Oncol. 2020. PMID: 32319587 Free PMC article.

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Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

Zhou M, Sandercock AM, Fraser CS, Ridlova G, Stephens E, Schenauer MR, Yokoi-Fong T, Barsky D, Leary JA, Hershey JW, Doudna JA, Robinson CV. Zhou M, et al. Among authors: sandercock am. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18139-44. doi: 10.1073/pnas.0801313105. Epub 2008 Jul 1. Proc Natl Acad Sci U S A. 2008. PMID: 18599441 Free PMC article.

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Topological models of heteromeric protein assemblies from mass spectrometry: application to the yeast eIF3:eIF5 complex.

Politis A, Schmidt C, Tjioe E, Sandercock AM, Lasker K, Gordiyenko Y, Russel D, Sali A, Robinson CV. Politis A, et al. Among authors: sandercock am. Chem Biol. 2015 Jan 22;22(1):117-28. doi: 10.1016/j.chembiol.2014.11.010. Epub 2014 Dec 24. Chem Biol. 2015. PMID: 25544043 Free PMC article.

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