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Inhibition of GCK-IV kinases dissociates cell death and axon regeneration in CNS neurons.

Patel AK, Broyer RM, Lee CD, Lu T, Louie MJ, La Torre A, Al-Ali H, Vu MT, Mitchell KL, Wahlin KJ, Berlinicke CA, Jaskula-Ranga V, Hu Y, Duan X, Vilar S, Bixby JL, Weinreb RN, Lemmon VP, Zack DJ, Welsbie DS. Patel AK, et al. Among authors: vilar s. Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33597-33607. doi: 10.1073/pnas.2004683117. Epub 2020 Dec 14. Proc Natl Acad Sci U S A. 2020. PMID: 33318207 Free PMC article.

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Structure-Based Optimization of Coumarin hA₃ Adenosine Receptor Antagonists.

Matos MJ, Vilar S, Vazquez-Rodriguez S, Kachler S, Klotz KN, Buccioni M, Delogu G, Santana L, Uriarte E, Borges F. Matos MJ, et al. Among authors: vilar s. J Med Chem. 2020 Mar 12;63(5):2577-2587. doi: 10.1021/acs.jmedchem.9b01572. Epub 2019 Dec 4. J Med Chem. 2020. PMID: 31738058

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Molecular Docking and Drug Discovery in β-Adrenergic Receptors.

Vilar S, Sobarzo-Sanchez E, Santana L, Uriarte E. Vilar S, et al. Curr Med Chem. 2017;24(39):4340-4359. doi: 10.2174/0929867324666170724101448. Curr Med Chem. 2017. PMID: 28738772 Review.

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High-throughput methods for combinatorial drug discovery.

Sun X, Vilar S, Tatonetti NP. Sun X, et al. Among authors: vilar s. Sci Transl Med. 2013 Oct 2;5(205):205rv1. doi: 10.1126/scitranslmed.3006667. Sci Transl Med. 2013. PMID: 24089409 Review.

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In Silico Prediction of P-glycoprotein Binding: Insights from Molecular Docking Studies.

Vilar S, Sobarzo-Sánchez E, Uriarte E. Vilar S, et al. Curr Med Chem. 2019;26(10):1746-1760. doi: 10.2174/0929867325666171129121924. Curr Med Chem. 2019. PMID: 29189117 Review.

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Adenosine Receptor Ligands: Coumarin-Chalcone Hybrids as Modulating Agents on the Activity of hARs.

Vazquez-Rodriguez S, Vilar S, Kachler S, Klotz KN, Uriarte E, Borges F, Matos MJ. Vazquez-Rodriguez S, et al. Among authors: vilar s. Molecules. 2020 Sep 19;25(18):4306. doi: 10.3390/molecules25184306. Molecules. 2020. PMID: 32961824 Free PMC article.

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Monoamine oxidase inhibitors: ten years of docking studies.

Ferino G, Vilar S, Matos MJ, Uriarte E, Cadoni E. Ferino G, et al. Among authors: vilar s. Curr Top Med Chem. 2012;12(20):2145-62. doi: 10.2174/156802612805220048. Curr Top Med Chem. 2012. PMID: 23231393 Review.

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Exploring the Multi-Target Performance of Mitochondriotropic Antioxidants against the Pivotal Alzheimer's Disease Pathophysiological Hallmarks.

Benfeito S, Fernandes C, Vilar S, Remião F, Uriarte E, Borges F. Benfeito S, et al. Among authors: vilar s. Molecules. 2020 Jan 9;25(2):276. doi: 10.3390/molecules25020276. Molecules. 2020. PMID: 31936622 Free PMC article.

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Predicting monoamine oxidase inhibitory activity through ligand-based models.

Vilar S, Ferino G, Quezada E, Santana L, Friedman C. Vilar S, et al. Curr Top Med Chem. 2012;12(20):2258-74. doi: 10.2174/156802612805219987. Curr Top Med Chem. 2012. PMID: 23231398 Free PMC article. Review.

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Recent structural advances of β1 and β2 adrenoceptors yield keys for ligand recognition and drug design.

Soriano-Ursúa MA, Trujillo-Ferrara JG, Correa-Basurto J, Vilar S. Soriano-Ursúa MA, et al. Among authors: vilar s. J Med Chem. 2013 Nov 14;56(21):8207-23. doi: 10.1021/jm400471z. Epub 2013 Aug 1. J Med Chem. 2013. PMID: 23862978 Review.

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