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Showing results for sarah kidney
Search for Sarah Widney instead (3 results)
Chronic Kidney Disease and Exposure to Nephrotoxic Metals.
Orr SE, Bridges CC. Orr SE, et al. Int J Mol Sci. 2017 May 12;18(5):1039. doi: 10.3390/ijms18051039. Int J Mol Sci. 2017. PMID: 28498320 Free PMC article. Review.
Chronic kidney disease (CKD) is a common progressive disease that is typically characterized by the permanent loss of functional nephrons. As injured nephrons become sclerotic and die, the remaining healthy nephrons undergo numerous structural, molecular, and functional ch …
Chronic kidney disease (CKD) is a common progressive disease that is typically characterized by the permanent loss of functional neph …
Food is medicine: actions to integrate food and nutrition into healthcare.
Downer S, Berkowitz SA, Harlan TS, Olstad DL, Mozaffarian D. Downer S, et al. BMJ. 2020 Jun 29;369:m2482. doi: 10.1136/bmj.m2482. BMJ. 2020. PMID: 32601089 Free PMC article. Review.
Sarah Downer and colleagues review new efforts to incorporate food and nutrition into prevention, management, and treatment of diet related disease in healthcare systems...
Sarah Downer and colleagues review new efforts to incorporate food and nutrition into prevention, management, and treatment of diet r
Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma.
McDermott DF, Huseni MA, Atkins MB, Motzer RJ, Rini BI, Escudier B, Fong L, Joseph RW, Pal SK, Reeves JA, Sznol M, Hainsworth J, Rathmell WK, Stadler WM, Hutson T, Gore ME, Ravaud A, Bracarda S, Suárez C, Danielli R, Gruenwald V, Choueiri TK, Nickles D, Jhunjhunwala S, Piault-Louis E, Thobhani A, Qiu J, Chen DS, Hegde PS, Schiff C, Fine GD, Powles T. McDermott DF, et al. Nat Med. 2018 Jun;24(6):749-757. doi: 10.1038/s41591-018-0053-3. Epub 2018 Jun 4. Nat Med. 2018. PMID: 29867230 Free PMC article. Clinical Trial.
Genetic variants of calcium and vitamin D metabolism in kidney stone disease.
Howles SA, Wiberg A, Goldsworthy M, Bayliss AL, Gluck AK, Ng M, Grout E, Tanikawa C, Kamatani Y, Terao C, Takahashi A, Kubo M, Matsuda K, Thakker RV, Turney BW, Furniss D. Howles SA, et al. Nat Commun. 2019 Nov 15;10(1):5175. doi: 10.1038/s41467-019-13145-x. Nat Commun. 2019. PMID: 31729369 Free PMC article.
Kidney stone disease (nephrolithiasis) is a major clinical and economic health burden with a heritability of ~45-60%. ...Our findings indicate that studies of genotype-guided precision-medicine approaches, including withholding vitamin D supplementation and targeting vitam
Kidney stone disease (nephrolithiasis) is a major clinical and economic health burden with a heritability of ~45-60%. ...Our findings
Macrophages in Renal Injury and Repair.
Huen SC, Cantley LG. Huen SC, et al. Annu Rev Physiol. 2017 Feb 10;79:449-469. doi: 10.1146/annurev-physiol-022516-034219. Annu Rev Physiol. 2017. PMID: 28192060 Review.
Acute kidney injury (AKI) is a growing global health concern, yet no treatment is currently available to prevent it or to promote kidney repair after injury. ...Emerging data from human biopsies also corroborate the presence of macrophages in AKI and their persisten …
Acute kidney injury (AKI) is a growing global health concern, yet no treatment is currently available to prevent it or to promote …
Pembrolizumab for management of patients with NSCLC and brain metastases: long-term results and biomarker analysis from a non-randomised, open-label, phase 2 trial.
Goldberg SB, Schalper KA, Gettinger SN, Mahajan A, Herbst RS, Chiang AC, Lilenbaum R, Wilson FH, Omay SB, Yu JB, Jilaveanu L, Tran T, Pavlik K, Rowen E, Gerrish H, Komlo A, Gupta R, Wyatt H, Ribeiro M, Kluger Y, Zhou G, Wei W, Chiang VL, Kluger HM. Goldberg SB, et al. Lancet Oncol. 2020 May;21(5):655-663. doi: 10.1016/S1470-2045(20)30111-X. Epub 2020 Apr 3. Lancet Oncol. 2020. PMID: 32251621 Free PMC article. Clinical Trial.
Treatment-related serious adverse events occurred in six (14%) of 42 patients and were pneumonitis (n=2), acute kidney injury, colitis, hypokalaemia, and adrenal insufficiency (n=1 each). ...
Treatment-related serious adverse events occurred in six (14%) of 42 patients and were pneumonitis (n=2), acute kidney injury, coliti …
Metabolomics assessment reveals oxidative stress and altered energy production in the heart after ischemic acute kidney injury in mice.
Fox BM, Gil HW, Kirkbride-Romeo L, Bagchi RA, Wennersten SA, Haefner KR, Skrypnyk NI, Brown CN, Soranno DE, Gist KM, Griffin BR, Jovanovich A, Reisz JA, Wither MJ, D'Alessandro A, Edelstein CL, Clendenen N, McKinsey TA, Altmann C, Faubel S. Fox BM, et al. Kidney Int. 2019 Mar;95(3):590-610. doi: 10.1016/j.kint.2018.10.020. Epub 2019 Jan 30. Kidney Int. 2019. PMID: 30709662 Free PMC article.
Acute kidney injury (AKI) is a systemic disease associated with widespread effects on distant organs, including the heart. ...These metabolomic effects were associated with significant cardiac ATP depletion and with echocardiographic evidence of diastolic dysfunction. In t …
Acute kidney injury (AKI) is a systemic disease associated with widespread effects on distant organs, including the heart. ...These m …
Association of Multiple Plasma Biomarker Concentrations with Progression of Prevalent Diabetic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study.
Schrauben SJ, Shou H, Zhang X, Anderson AH, Bonventre JV, Chen J, Coca S, Furth SL, Greenberg JH, Gutierrez OM, Ix JH, Lash JP, Parikh CR, Rebholz CM, Sabbisetti V, Sarnak MJ, Shlipak MG, Waikar SS, Kimmel PL, Vasan RS, Feldman HI, Schelling JR; CKD Biomarkers Consortium and the Chronic Renal Insufficiency Cohort (CRIC) Study Investigators. Schrauben SJ, et al. J Am Soc Nephrol. 2021 Jan;32(1):115-126. doi: 10.1681/ASN.2020040487. Epub 2020 Oct 29. J Am Soc Nephrol. 2021. PMID: 33122288
BACKGROUND: Although diabetic kidney disease is the leading cause of ESKD in the United States, identifying those patients who progress to ESKD is difficult. ...Weighted Cox regression models related biomarkers to progression of diabetic kidney disease, and mixed-ef …
BACKGROUND: Although diabetic kidney disease is the leading cause of ESKD in the United States, identifying those patients who progre …
Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma.
Wallin JJ, Bendell JC, Funke R, Sznol M, Korski K, Jones S, Hernandez G, Mier J, He X, Hodi FS, Denker M, Leveque V, Cañamero M, Babitski G, Koeppen H, Ziai J, Sharma N, Gaire F, Chen DS, Waterkamp D, Hegde PS, McDermott DF. Wallin JJ, et al. Nat Commun. 2016 Aug 30;7:12624. doi: 10.1038/ncomms12624. Nat Commun. 2016. PMID: 27571927 Free PMC article. Clinical Trial.
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