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Thalassemia in India.
Colah RB, Seth T. Colah RB, et al. Hemoglobin. 2022 Jan;46(1):20-26. doi: 10.1080/03630269.2021.2008958. Hemoglobin. 2022. PMID: 35950587 Review.
The beta-thalassemias are prevalent with an estimated 7500-12000 new births each year. Hb S (HBB: c.20A>T) and Hb E (HBB: c.79G>A) are also common regionally. Over 80 beta-thalassemia (beta-thal) mutations have been characterized in Indians. ...
The beta-thalassemias are prevalent with an estimated 7500-12000 new births each year. Hb S (HBB: c.20A>T) and Hb E (HBB: c.79G&gt …
Circulating human microRNA biomarkers of oxalic acid-induced acute kidney injury.
Shihana F, Joglekar MV, Raubenheimer J, Hardikar AA, Buckley NA, Seth D. Shihana F, et al. Arch Toxicol. 2020 May;94(5):1725-1737. doi: 10.1007/s00204-020-02679-5. Epub 2020 Feb 21. Arch Toxicol. 2020. PMID: 32086547
Thirteen microRNAs were significantly downregulated in acute kidney injury patients compared to NOAKI within 8-h post-ingestion. Five microRNAs (miR-20a, miR-92a, miR-93, miR-195, miR-451) had a highly significant correlation with normalized urinary albumin, serum creatini …
Thirteen microRNAs were significantly downregulated in acute kidney injury patients compared to NOAKI within 8-h post-ingestion. Five microR …
Urinary versus serum microRNAs in human oxalic acid poisoning: Contrasting signals and performance.
Shihana F, Mohamed F, Joglekar MV, Hardikar AA, Seth D, Buckley NA. Shihana F, et al. Toxicol Lett. 2020 Nov 1;334:21-26. doi: 10.1016/j.toxlet.2020.09.003. Epub 2020 Sep 7. Toxicol Lett. 2020. PMID: 32910981

Most urine microRNA in the validation cohort were significantly upregulated (25/30, fold change >2.8 and p < 0.05) in AKIN2/3 patients compared to No AKI. Four urinary microRNAs (miR-191, miR-19b, miR-20a and miR-30b) had good diagnostic performance (AUC greater than

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Most urine microRNA in the validation cohort were significantly upregulated (25/30, fold change >2.8 and p < 0.05) in AKIN2/3 patients

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Aziridine-Allylsilane-Mediated Total Synthesis of (-)-Yohimbane.
Bergmeier SC, Seth PP. Bergmeier SC, et al. J Org Chem. 1999 Apr 30;64(9):3237-3243. doi: 10.1021/jo9825097. J Org Chem. 1999. PMID: 11674426
Treatment of optically pure aziridine-allylsilane 16 with BF(3).OEt(2) provided a mixture of aminomethyl substituted carbocycles trans-20a and cis-20b in excellent yield and modest diastereoselectivity (trans/cis 3:1). ...
Treatment of optically pure aziridine-allylsilane 16 with BF(3).OEt(2) provided a mixture of aminomethyl substituted carbocycles trans-20 …