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Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age-Related Blood-Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice.
Csik B, Nyúl-Tóth Á, Gulej R, Patai R, Kiss T, Delfavero J, Nagaraja RY, Balasubramanian P, Shanmugarama S, Ungvari A, Chandragiri SS, Kordestan KV, Nagykaldi M, Mukli P, Yabluchanskiy A, Negri S, Tarantini S, Conley S, Oh TG, Ungvari Z, Csiszar A. Csik B, et al. Among authors: negri s. Aging Cell. 2025 Jul;24(7):e70048. doi: 10.1111/acel.70048. Epub 2025 Apr 1. Aging Cell. 2025. PMID: 40167015 Free PMC article.
Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging.
Milan M, Troyano-Rodriguez E, Ihuoma J, Negri S, Rudraboina R, Kosmider A, Awasthi S, Balasubramanian P, Conley S, Yabluchanskiy A, Csiszar A, Ungvari Z, de Cabo R, Tarantini S. Milan M, et al. Among authors: negri s. Aging Cell. 2026 Feb;25(2):e70372. doi: 10.1111/acel.70372. Aging Cell. 2026. PMID: 41521387 Free PMC article. Review.
Effects of NAD+ supplementation with oral nicotinamide riboside on vascular health and cognitive function in older adults with peripheral artery disease: Results from a pilot 4-week open-label clinical trial.
Szarvas Z, Reyff ZA, Peterfi A, Pinto CB, Owens CD, Kaposzta Z, Mukli P, Pinaffi-Langley ACDC, Adams CA, Muranyi M, Palacios FS, Hawkins B, Baur JA, Velez FS, Prodan CI, Kirkpatrick AC, Csiszar A, Ungvari Z, Balasubramanian P, Negri S, Tarantini S, Ding K, Buelow AA, Akbari A, Kellawan JM, Yabluchanskiy A. Szarvas Z, et al. Among authors: negri s. J Pharmacol Exp Ther. 2025 Jul;392(7):103607. doi: 10.1016/j.jpet.2025.103607. Epub 2025 May 14. J Pharmacol Exp Ther. 2025. PMID: 40479886 Clinical Trial.
Time-restricted feeding improves aortic endothelial relaxation by enhancing mitochondrial function and attenuating oxidative stress in aged mice.
Milan M, Brown J, O'Reilly CL, Bubak MP, Negri S, Balasubramanian P, Dhanekula AS, Pharaoh G, Reyff Z, Ballard C, Shi H, Yabluchanskiy A, Rudolph MC, Ungvari Z, Marcinek DJ, Miller BF, Van Remmen H, Tarantini S. Milan M, et al. Among authors: negri s. Redox Biol. 2024 Jul;73:103189. doi: 10.1016/j.redox.2024.103189. Epub 2024 May 15. Redox Biol. 2024. PMID: 38788541 Free PMC article.
Endothelial Colony-Forming Cells (ECFCs) in cerebrovascular aging: Focus on the pathogenesis of Vascular Cognitive Impairment and Dementia (VCID), and treatment prospects.
Negri S, Reyff Z, Troyano-Rodriguez E, Milan M, Ihuoma J, Tavakol S, Shi H, Patai R, Jiang R, Mohon J, Boma-Iyaye J, Ungvari Z, Csiszar A, Yabluchanskiy A, Moccia F, Tarantini S. Negri S, et al. Ageing Res Rev. 2025 Feb;104:102672. doi: 10.1016/j.arr.2025.102672. Epub 2025 Jan 28. Ageing Res Rev. 2025. PMID: 39884362 Review.
A Minimally Invasive Framework Reveals Region-Specific Cerebrovascular Remodeling in Aging Using Intravital Functional Ultrasound Imaging and Ultrasound Localization Microscopy (fUS-ULM).
Negri S, Nyul-Toth A, Milan M, Troyano-Rodriguez E, Tavakol S, Ihuoma J, Reyff Z, Rudraboina R, Gulej R, Jang R, Csiszar A, Ungvari Z, Cleuren A, Miller DR, Yabluchanskiy A, Tanter M, Tarantini S. Negri S, et al. Adv Sci (Weinh). 2026 Jan;13(1):e10754. doi: 10.1002/advs.202510754. Epub 2025 Sep 14. Adv Sci (Weinh). 2026. PMID: 40946188 Free PMC article.
Endothelial IGF- 1R deficiency disrupts microvascular homeostasis, impairing skeletal muscle perfusion and endurance: implications for age-related sarcopenia.
Nyul-Toth A, Shanmugarama S, Patai R, Gulej R, Faakye J, Nagy D, Nagykaldi M, Kiss T, Csipo T, Milan M, Ekambaram S, Negri S, Nagaraja RY, Csiszar A, Brown JL, Van Remmen H, Ungvari A, Yabluchanskiy A, Tarantini S, Ungvari Z. Nyul-Toth A, et al. Among authors: negri s. Geroscience. 2025 Jun;47(3):4187-4204. doi: 10.1007/s11357-025-01653-2. Epub 2025 Apr 8. Geroscience. 2025. PMID: 40199795 Free PMC article.
54 results