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p66Shc protein through a redox mechanism enhances the progression of prostate cancer cells towards castration-resistance.
Miller DR, Ingersoll MA, Chatterjee A, Baker B, Shrishrimal S, Kosmacek EA, Zhu Y, Cheng PW, Oberley-Deegan RE, Lin MF. Miller DR, et al. Among authors: Shrishrimal S. Free Radic Biol Med. 2019 Aug 1;139:24-34. doi: 10.1016/j.freeradbiomed.2019.05.015. Epub 2019 May 14. Free Radic Biol Med. 2019. PMID: 31100478
Reactive Oxygen Species Drive Epigenetic Changes in Radiation-Induced Fibrosis.
Shrishrimal S, Kosmacek EA, Oberley-Deegan RE. Shrishrimal S, et al. Oxid Med Cell Longev. 2019 Feb 6;2019:4278658. doi: 10.1155/2019/4278658. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 30881591 Free PMC article. Review.
Manganese porphyrin, MnTE-2-PyP, treatment protects the prostate from radiation-induced fibrosis (RIF) by activating the NRF2 signaling pathway and enhancing SOD2 and sirtuin activity.
Shrishrimal S, Chatterjee A, Kosmacek EA, Davis PJ, McDonald JT, Oberley-Deegan RE. Shrishrimal S, et al. Free Radic Biol Med. 2020 Mar 25;152:255-270. doi: 10.1016/j.freeradbiomed.2020.03.014. Online ahead of print. Free Radic Biol Med. 2020. PMID: 32222469
MnTE-2-PyP, a manganese porphyrin, reduces cytotoxicity caused by irradiation in a diabetic environment through the induction of endogenous antioxidant defenses.
Chatterjee A, Kosmacek EA, Shrishrimal S, McDonald JT, Oberley-Deegan RE. Chatterjee A, et al. Among authors: Shrishrimal S. Redox Biol. 2020 Apr 21;34:101542. doi: 10.1016/j.redox.2020.101542. Online ahead of print. Redox Biol. 2020. PMID: 32361681 Free PMC article.